What is he best known for?
The fields of study he is best known for:
Sidney D. Nelson mainly focuses on Acetaminophen, Metabolite, Biochemistry, Pharmacology and Glutathione.
His work carried out in the field of Acetaminophen brings together such families of science as Ethanol, Drug alcohol interaction, Antipyretic, Cytochrome P450 and Mitochondrion.
His Metabolite research incorporates elements of Liver injury, Macromolecule, Benzoquinone, Stereochemistry and Cytochrome.
His research integrates issues of Covalent bond and Toxicity in his study of Biochemistry.
His study on Pharmacokinetics is often connected to Text mining as part of broader study in Pharmacology.
His Glutathione study combines topics from a wide range of disciplines, such as Oxidative phosphorylation, Sulfate conjugate, Hydrogen peroxide and Bovine serum albumin.
His most cited work include:
- N-acetyl-p- benzoquinone imine a cytochrome P-450 mediated oxidation product of acetaminophen (861 citations)
- Isoniazid liver injury: clinical spectrum, pathology, and probable pathogenesis (409 citations)
- Molecular mechanisms of the hepatotoxicity caused by acetaminophen. (382 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Biochemistry, Metabolite, Glutathione, Acetaminophen and Stereochemistry.
Many of his studies involve connections with topics such as Toxicity and Biochemistry.
Sidney D. Nelson merges many fields, such as Metabolite and Menthofuran, in his writings.
As part of one scientific family, Sidney D. Nelson deals mainly with the area of Glutathione, narrowing it down to issues related to the 1,2-Dibromo-3-chloropropane, and often DNA damage.
His work is dedicated to discovering how Acetaminophen, NAPQI are connected with Benzoquinone and other disciplines.
His biological study spans a wide range of topics, including Adduct, Kinetic isotope effect and Active site.
He most often published in these fields:
- Biochemistry (40.86%)
- Metabolite (26.07%)
- Glutathione (25.29%)
What were the highlights of his more recent work (between 2005-2019)?
- Biochemistry (40.86%)
- Stereochemistry (19.46%)
- Glutathione (25.29%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Biochemistry, Stereochemistry, Glutathione, Pharmacology and Metabolite.
His studies in Stereochemistry integrate themes in fields like Cytochrome, Molecule, Cooperativity and Kinetic isotope effect.
His Glutathione study combines topics in areas such as Microsome, Acetaminophen, Cytochrome P450 reductase and Heme.
His Acetaminophen research is multidisciplinary, relying on both Protein kinase A, Phosphorylation, Liver injury, NAPQI and Molecular biology.
He interconnects Gene expression, CYP3A4, Viability assay, Toxicity and CYP3A in the investigation of issues within Pharmacology.
His research investigates the connection with Metabolite and areas like Adduct which intersect with concerns in Structural isomer, Hepatotoxin and Thiophene.
Between 2005 and 2019, his most popular works were:
- Managing the challenge of chemically reactive metabolites in drug development (301 citations)
- High-throughput screening and characterization of reactive metabolites using polarity switching of hybrid triple quadrupole linear ion trap mass spectrometry. (88 citations)
- Mechanism-Based Inactivation of Cytochrome P450 3A4 by Lapatinib (79 citations)
In his most recent research, the most cited papers focused on:
The scientist’s investigation covers issues in Metabolite, Stereochemistry, Pharmacology, Cytochrome P450 and Glutathione.
His research on Metabolite frequently links to adjacent areas such as Adduct.
His study in Stereochemistry is interdisciplinary in nature, drawing from both Cooperativity, Hydroxylation, Residue, Cytochrome and Peptide.
The study incorporates disciplines such as Oxidative phosphorylation, Programmed cell death, Hepatocyte, Viability assay and Mitochondrion in addition to Pharmacology.
His Cytochrome P450 study improves the overall literature in Biochemistry.
His Glutathione study combines topics from a wide range of disciplines, such as Microsome and Heme.
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