What is he best known for?
The fields of study he is best known for:
- Enzyme
- Organic chemistry
- Biochemistry
His main research concerns Metabolite, Biochemistry, Glutathione, Pharmacology and Stereochemistry.
His Metabolite study combines topics in areas such as Microsome, Chromatography and Tandem mass spectrometry.
His research on Biochemistry often connects related areas such as In vivo.
The concepts of his Glutathione study are interwoven with issues in Adduct, Troglitazone, Quinone methide and Mass spectrometry.
His research integrates issues of Glucuronidation and Drug discovery in his study of Pharmacology.
Thomas A. Baillie has researched Stereochemistry in several fields, including Cytochrome, Metabolism, Binding site and Active site.
His most cited work include:
- The resurgence of covalent drugs (915 citations)
- Drug−Protein Adducts: An Industry Perspective on Minimizing the Potential for Drug Bioactivation in Drug Discovery and Development (561 citations)
- Structural alert/reactive metabolite concept as applied in medicinal chemistry to mitigate the risk of idiosyncratic drug toxicity: a perspective based on the critical examination of trends in the top 200 drugs marketed in the United States. (382 citations)
What are the main themes of his work throughout his whole career to date?
Thomas A. Baillie mostly deals with Biochemistry, Metabolite, Stereochemistry, Metabolism and Pharmacology.
His research investigates the connection between Biochemistry and topics such as In vivo that intersect with problems in In vitro.
His study focuses on the intersection of Metabolite and fields such as Chromatography with connections in the field of Ion.
His work on Enantiomer as part of his general Stereochemistry study is frequently connected to Reactive intermediate, thereby bridging the divide between different branches of science.
Thomas A. Baillie combines subjects such as Fatty acid and Hydroxylation with his study of Metabolism.
His Drug metabolism research is multidisciplinary, incorporating elements of Pharmaceutical industry and Drug discovery.
He most often published in these fields:
- Biochemistry (32.68%)
- Metabolite (31.71%)
- Stereochemistry (31.22%)
What were the highlights of his more recent work (between 2006-2021)?
- Drug discovery (13.17%)
- Drug (13.17%)
- Pharmacology (24.39%)
In recent papers he was focusing on the following fields of study:
Thomas A. Baillie mainly focuses on Drug discovery, Drug, Pharmacology, Drug metabolism and Computational biology.
The Drug discovery study combines topics in areas such as Covalent binding, Risk analysis, Liquid chromatography–mass spectrometry and Protein mass spectrometry.
In general Drug, his work in Drug toxicity is often linked to Animal species linking many areas of study.
His studies deal with areas such as Microsome, Toxicity and Hydroxylation as well as Pharmacology.
He usually deals with Microsome and limits it to topics linked to Nitroso and Metabolite.
His Metabolite research incorporates elements of Chromatography and Tandem mass spectrometry.
Between 2006 and 2021, his most popular works were:
- The resurgence of covalent drugs (915 citations)
- Structural alert/reactive metabolite concept as applied in medicinal chemistry to mitigate the risk of idiosyncratic drug toxicity: a perspective based on the critical examination of trends in the top 200 drugs marketed in the United States. (382 citations)
- Managing the challenge of chemically reactive metabolites in drug development (301 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Organic chemistry
- Biochemistry
Thomas A. Baillie mainly investigates Drug discovery, Pharmacology, Drug, Drug metabolism and Pharmaceutical industry.
His Drug discovery research includes themes of Tandem mass spectrometry, Liquid chromatography–mass spectrometry and First line.
His specific area of interest is Pharmacology, where Thomas A. Baillie studies Drug recall.
His work carried out in the field of Drug brings together such families of science as Covalent bond and Toxicity.
His Drug metabolism research includes elements of Pharmacokinetics, Biotransformation and Preclinical toxicity.
His studies in Pharmaceutical industry integrate themes in fields like Drug induced toxicity, Adverse effect and Pharmacogenomics.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
