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Neal Castagnoli

Neal Castagnoli

D-Index & Metrics

Chemistry

D-Index
56
Citations
12336
World Ranking
11543
National Ranking
3116

Research.com Recognitions

  • 2009 - Fellow of the American Chemical Society
  • 1984 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Neal Castagnoli is affiliated with Virginia Tech in the United States. Their research primarily focuses on the field of Chemistry with notable contributions in Electrical and Electronic Engineering, Physical and Theoretical Chemistry, and Electrochemistry.

Their work extensively covers topics such as:

  • Electrochemical sensors and biosensors
  • Photochemistry and Electron Transfer Studies
  • Electrochemical Analysis and Applications

Castagnoli has published in several venues, including:

  • Chemistry - A European Journal
  • UNC Libraries

Recent papers authored or co-authored by Neal Castagnoli include:

  • Frontispiece: Evidence for a Proton-Coupled Electron Transfer Mechanism in a Biomimetic System for Monoamine Oxidase B Catalysis (2020), published in Chemistry - A European Journal
  • Brain levels of the neurotoxic pyridinium metabolite HPP+ and extrapyramidal symptoms in haloperidol-treated mice (2020), published in UNC Libraries

Their frequent collaborators include Akiko Nakamura, Marwa Abdel Latif, Paul A. Deck, James M. Tanko, and James J. Crowley.

Neal Castagnoli has been recognized as a Fellow of the American Chemical Society since 2009 and as a Fellow of the American Association for the Advancement of Science (AAAS) since 1984.

Best Publications

  • Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase.

    Kan Chiba;Anthony Trevor;Neal Castagnoli

  • A convenient synthesis of quinones from hydroquinone dimethyl ethers. Oxidative demethylation with ceric ammonium nitrate

    Peyton. Jacob;Patrick S. Callery;Alexander T. Shulgin;Neal. Castagnoli

  • Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomes

    Kan Chiba;Anthony J. Trevor;Neal Castagnoli

  • Biochemical events in the development of parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

    Thomas P. Singer;Neal Castagnoli;Rona R. Ramsay;Anthony J. Trevor

  • Demonstration of Isoleucine 199 as a Structural Determinant for the Selective Inhibition of Human Monoamine Oxidase B by Specific Reversible Inhibitors

    Frantisek Hubálek;Claudia Binda;Ashraf Khalil;Min Li

  • Oxidation of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by monoamine oxidases A and B and suicide inactivation of the enzymes by MPTP

    James I. Salach;James I. Salach;Thomas P. Singer;Thomas P. Singer;Neal Castagnoli;Anthony Trevor

  • Interactions of nitrogen-containing xenobiotics with monoamine oxidase (MAO) isozymes A and B: SAR studies on MAO substrates and inhibitors.

    Amit S. Kalgutkar;Deepak K. Dalvie;Neal Castagnoli;Timothy J. Taylor

  • A2A antagonist prevents dopamine agonist-induced motor complications in animal models of Parkinson’s disease

    F Bibbiani;J.D Oh;J.P Petzer;N Castagnoli

  • V. Potential bioactivation pathways for the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

    N. Castagnoli;K. Chiba;A.J. Trevor

  • MPP(+)-LIKE NEUROTOXICITY OF A PYRIDINIUM METABOLITE DERIVED FROM HALOPERIDOL - IN-VIVO MICRODIALYSIS AND IN-VITRO MITOCHONDRIAL STUDIES

    H Rollema;M Skolnik;J Dengelbronner;K Igarashi

  • IDENTIFICATION OF A POTENTIALLY NEUROTOXIC PYRIDINIUM METABOLITE OF HALOPERIDOL IN RATS

    Babu Subramanyam;Hans Rollema;Thomas Woolf;Neal Castagnoli

  • Neuroprotection by caffeine and more specific A2A receptor antagonists in animal models of Parkinson’s disease

    Michael A. Schwarzschild;Kui Xu;Emin Oztas;Jacobus P. Petzer

  • Studies on the molecular mechanism of bioactivation of the selective nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

    K Chiba;L A Peterson;K P Castagnoli;A J Trevor

  • The condensation of succinic anhydride with benzylidinemethylamine. A stereoselective synthesis of trans- and cis-1-methyl-4-carbosy-5-phenyl-2-pyrrolidinone.

    Neal Castagnoli

  • Selective inhibitors of monoamine oxidase (MAO-A and MAO-B) as probes of its catalytic site and mechanism.

    Amit S. Kalgutkar;Neal Castagnoli;Bernard Testa

  • 8-(3-Chlorostyryl)caffeine may attenuate MPTP neurotoxicity through dual actions of monoamine oxidase inhibition and A2A receptor antagonism.

    Jiang Fan Chen;Salome Steyn;Roland Staal;Jacobus P. Petzer

  • The Neuronal Nitric Oxide Synthase Inhibitor 7-Nitroindazole Also Inhibits the Monoamine Oxidase-B-Catalyzed Oxidation of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine

    Kay Castagnoli;Sonya Palmer;Andrea Anderson;Tjerk Bueters

  • Inhibition of monoamine oxidase B by selective adenosine A2A receptor antagonists.

    Jacobus P Petzer;Salome Steyn;Kay P Castagnoli;Jiang Fan Chen

  • STUDIES ON THE IN VITRO CONVERSION OF HALOPERIDOL TO A POTENTIALLY NEUROTOXIC PYRIDINIUM METABOLITE

    Babu Subramanyam;Thomas Woolf;Neal Castagnoli

  • Inhibition of monoamine oxidase contributes to the protective effect of 7-nitroindazole against MPTP neurotoxicity

    Donato A. Di Monte;Joyce E. Royland;Andrea Anderson;Kay Castagnoli

  • Isolation and characterization of a monoamine oxidase inhibitor from tobacco leaves.

    Ashraf A. Khalil;Salome Steyn;Neal Castagnoli

Frequent Co-Authors

Johan Wouters
Johan Wouters University of Namur
Thomas P. Singer
Thomas P. Singer University of California, San Francisco
Michael A. Schwarzschild
Michael A. Schwarzschild Harvard University
Dale E. Edmondson
Dale E. Edmondson Emory University
Amit S. Kalgutkar
Amit S. Kalgutkar Pfizer (United States)
Thomas A. Baillie
Thomas A. Baillie University of Washington
Peyton Jacob
Peyton Jacob University of California, San Francisco
Mark Cushman
Mark Cushman Purdue University West Lafayette
Darryl W. Eyles
Darryl W. Eyles University of Queensland
Jiang-Fan Chen
Jiang-Fan Chen Boston University

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