World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
74
Citations
18439
World Ranking
4735
National Ranking
1491

Biology and Biochemistry

D-Index
73
Citations
17751
World Ranking
5981
National Ranking
2822

Research.com Recognitions

  • 1959 - Fellow of John Simon Guggenheim Memorial Foundation
  • 1951 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Thomas P. Singer was affiliated with the University of California, San Francisco in the United States. Their research contributed to the field of Medicine, with significant focus on subfields such as Radiology, Nuclear Medicine and Imaging, Oncology, Immunology, Molecular Biology, and Biomedical Engineering.

The primary topics of their work included Monoclonal and Polyclonal Antibodies Research, CAR-T cell therapy research, Immunotherapy and Immune Responses, Nanofabrication and Lithography Techniques, vaccines and immunoinformatics approaches, Xenotransplantation and immune response, as well as Flood Risk Assessment and Management.

Their recent publications reflected a diverse range of research interests and appeared in notable scientific venues. These included:

  • "Human immunocompetent Organ-on-Chip platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies" (2021) published in eLife
  • "A humanized minipig model for the toxicological testing of therapeutic recombinant antibodies" (2022) published in Nature Biomedical Engineering
  • "DEEP LEARNING APPLIED TO WATER SEGMENTATION" (2020) published in The international archives of the photogrammetry, remote sensing and spatial information sciences/International archives of the photogrammetry, remote sensing and spatial information sciences
  • "Unraveling the deep learning gearbox in optical coherence tomography image segmentation towards explainable artificial intelligence" (2021) published in Communications Biology
  • "Managing the Impact of Immunogenicity in an Era of Immunotherapy: From Bench to Bedside" (2021) published in Journal of Pharmaceutical Sciences

The scientist frequently collaborated with a group of coauthors who contributed to various projects. The most frequent collaborators included Guido Steiner, Ekaterina Breous-Nystrom, Adrian Roth, Katharine Bray-French, and Céline Marban-Doran.

Their research was regularly published in venues such as the Journal of Proteome Research, eLife, Nature Biomedical Engineering, The international archives of the photogrammetry, remote sensing and spatial information sciences, and Communications Biology, with multiple contributions to some of these journals.

Thomas P. Singer received recognition as a Fellow of the John Simon Guggenheim Memorial Foundation, awarded in both 1951 and 1959.

Best Publications

  • Advances in Our Understanding of the Mechanisms of the Neurotoxicity of MPTP and Related Compounds

    Keith F. Tipton;Thomas P. Singer

  • Energy-dependent uptake of N-methyl-4-phenylpyridinium, the neurotoxic metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, by mitochondria.

    R R Ramsay;T P Singer

  • Determination of the activity of succinate, NADH, choline, and alpha-glycerophosphate dehydrogenases.

    Thomas P. Singer

  • Limitations of the Phenazine Methosulphate Assay for Succinic and Related Dehydrogenases

    Unknown

  • Inactivation of succinate dehydrogenase by 3-nitropropionate.

    C J Coles;D E Edmondson;T P Singer

  • Mammalian succinate dehydrogenase.

    Brian A.C. Ackrell;Edna B. Kearney;Thomas P. Singer

  • Biochemical events in the development of parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

    Thomas P. Singer;Neal Castagnoli;Rona R. Ramsay;Anthony J. Trevor

  • Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic parkinsonism

    Rona R. Ramsay;Rona R. Ramsay;James I. Salach;Jahan Dadgar;Jahan Dadgar;Thomas P. Singer;Thomas P. Singer

  • Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+.

    Rona R. Ramsay;Rona R. Ramsay;James I. Salach;James I. Salach;Thomas P. Singer;Thomas P. Singer

  • Studies on the Respiratory Chain-linked Dihydrodiphosphopyridine Nucleotide Dehydrogenase

    Unknown

  • Oxidation of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by monoamine oxidases A and B and suicide inactivation of the enzymes by MPTP

    James I. Salach;James I. Salach;Thomas P. Singer;Thomas P. Singer;Neal Castagnoli;Anthony Trevor

  • The Covalently‐Bound Flavin of Hepatic Monoamine Oxidase

    Edna B. Kearney;James I. Salach;Wolfram H. Walker;Richard L. Seng

  • Mechanism of the neurotoxicity of MPTP. An update.

    Thomas P. Singer;Rona R. Ramsay;Rona R. Ramsay

  • Studies on the Respiratory Chain-linked Reduced Nicotinamide Adenine Dinucleotide Dehydrogenase XIII. BINDING SITES OF ROTENONE, PIERICIDIN A, AND AMYTAL IN THE RESPIRATORY CHAIN

    Douglas J. Horgan;Douglas J. Horgan;Thomas P. Singer;Thomas P. Singer;J. E. Casida

  • Interaction of 1-methyl-4-phenylpyridinium ion (MPP+) and its analogs with the rotenone/piericidin binding site of NADH dehydrogenase.

    Rona R. Ramsay;Matthew J. Krueger;Stephen K. Youngster;Martin R. Gluck

  • Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP

    Rona R. Ramsay;Jahan Dadgar;Anthony Trevor;Thomas P. Singer

  • Studies on the respiratory chain-linked reduced nicotinamide adenine dinucleotide dehydrogenase. XIV. Location of the sites of inhibition of rotenone, barbiturates, and piericidin by means of electron paramagnetic resonance spectroscopy.

    Graham Palmer;Douglas J. Horgan;Douglas J. Horgan;Howard Tisdale;Howard Tisdale;Thomas P. Singer;Thomas P. Singer

  • NADH-quinone oxidoreductase: PSST subunit couples electron transfer from iron–sulfur cluster N2 to quinone

    F Schuler;T Yano;S Di Bernardo;T Yagi

  • The covalently-bound flavin of hepatic monoamine oxidase. 2. Identification and properties of cysteinyl riboflavin.

    Wolfram H. Walker;Edna B. Kearney;Richard L. Seng;Thomas P. Singer

  • The structure of the covalent adduct formed by the interaction of 3-dimethylamino-1-propyne and the flavine of mitochondrial amine oxidase.

    A L Maycock;R H Abeles;J I Salach;T P Singer

  • Nucleophilicities and carbon basicities of pyridines.

    Frank Brotzel;Bernhard Kempf;Thomas Singer;Hendrik Zipse

  • Studies on the Respiratory Chain-linked Reduced Nicotinamide Adenine Dinucleotide Dehydrogenase: XVII. REACTION SITES OF PIERICIDIN A AND ROTENONE

    Menachem Gutman;Thomas P. Singer;J. E. Casida

Frequent Co-Authors

Rona R. Ramsay
Rona R. Ramsay University of St Andrews
Helmut Beinert
Helmut Beinert University of Wisconsin–Madison
Dale E. Edmondson
Dale E. Edmondson Emory University
Michael K. Johnson
Michael K. Johnson University of Georgia
John E. Casida
John E. Casida University of California, Berkeley
Neal Castagnoli
Neal Castagnoli Virginia Tech
Richard H. Holm
Richard H. Holm Harvard University
Andrei D. Vinogradov
Andrei D. Vinogradov Lomonosov Moscow State University
Sandro Ghisla
Sandro Ghisla University of Konstanz
Lester Packer
Lester Packer University of Southern California

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring chemistry in the USA opens various pathways into specialized fields, including forensic science and criminal justice. For students interested in applying chemical principles to legal investigations, pursuing one of the best online colleges for forensic science offers an accessible route to gain relevant skills without the need to relocate.

Additionally, those fascinated by the psychological aspects of crime can enhance their expertise through a masters in forensic psychology online. This degree blends psychology with forensic principles, preparing graduates for interdisciplinary roles in the justice system.

Understanding the landscape of forensic career paths and salary is critical for making informed decisions about education and job options. These insights can guide students toward careers that combine chemistry with law enforcement, from crime lab analyst to toxicologist.

Considering tuition and fees is also essential when choosing a program. The cost of an online degree can vary widely, but resources on criminal justice degree price help prospective students budget and plan their education effectively.

Best Scientists Citing Thomas P. Singer