World's Best Scientists 2026 revealed!
Award Badge
Chemistry
Netherlands
2025

D-Index & Metrics

Chemistry

D-Index
79
Citations
22506
World Ranking
3605
National Ranking
84

Research.com Recognitions

  • 2025 - Research.com Chemistry in Netherlands Leader Award
  • 2022 - Research.com Chemistry in Netherlands Leader Award

Overview

Marco W. Fraaije is affiliated with the University of Groningen in the Netherlands, specializing in research within biochemistry, genetics, and molecular biology. Their work encompasses various subfields including molecular biology, materials chemistry, plant science, biomedical engineering, and organic chemistry.

Their research focuses on several main topics, notably:

  • Enzyme Catalysis and Immobilization
  • Microbial Metabolic Engineering and Bioproduction
  • Enzyme-mediated dye degradation
  • Photosynthetic Processes and Mechanisms
  • Amino Acid Enzymes and Metabolism
  • Enzyme Structure and Function
  • Biofuel production and bioconversion

Marco W. Fraaije has contributed extensively to scientific literature with 156 publications in their main field of study. Frequent publication venues where their work appears include:

  • Journal of Biological Chemistry
  • ChemBioChem
  • FEBS Journal
  • ACS Catalysis
  • ChemCatChem

Recent papers authored or co-authored include:

  • "Approaching boiling point stability of an alcohol dehydrogenase through computationally-guided enzyme engineering," 2020, eLife
  • "Structure of a robust bacterial protein cage and its application as a versatile biocatalytic platform through enzyme encapsulation," 2020, Biochemical and Biophysical Research Communications
  • "Production of indigo through the use of a dual-function substrate and a bifunctional fusion enzyme," 2020, Enzyme and Microbial Technology
  • "Production of Hydroxy Acids: Selective Double Oxidation of Diols by Flavoprotein Alcohol Oxidase," 2020, Angewandte Chemie International Edition
  • "Evolution of enzyme functionality in the flavin-containing monooxygenases," 2023, Nature Communications

The frequent co-authors collaborating with Marco W. Fraaije include:

  • Andrea Mattevi
  • María Laura Mascotti
  • H.J. Rozeboom
  • Miloš Trajković
  • Nikola Lončar

Best Publications

  • Flavoprotein monooxygenases, a diverse class of oxidative biocatalysts.

    W.J.H. van Berkel;N.M. Kamerbeek;M.W. Fraaije

  • Flavoenzymes: diverse catalysts with recurrent features

    Marco W. Fraaije;Andrea Mattevi

  • Bacterial enzymes involved in lignin degradation.

    Gonzalo de Gonzalo;Dana I Colpa;Mohamed H M Habib;Mohamed H M Habib;Marco W Fraaije

  • Cascade Reactions in Multicompartmentalized Polymersomes

    Ruud J.R.W. Peters;Maïté Marguet;Maïté Marguet;Sébastien Marais;Marco W. Fraaije

  • The possible role of matrix metalloproteinase (MMP)-2 and MMP-9 in cancer, e.g. acute leukemia

    G. Klein;Edo Vellenga;Marco Fraaije;Willem Kamps

  • Same Substrate, Many Reactions: Oxygen Activation in Flavoenzymes

    Elvira Romero;J Rubén Gómez Castellanos;Giovanni Gadda;Marco W Fraaije

  • Rational Engineering of a Flavoprotein Oxidase for Improved Direct Oxidation of Alcohols to Carboxylic Acids.

    Mathias Pickl;Christoph K Winkler;Silvia M Glueck;Marco W Fraaije

  • Crystal structure of a Baeyer-Villiger monooxygenase.

    Enrico Malito;Andrea Alfieri;Marco W. Fraaije;Andrea Mattevi

  • NARROW LEAF 7 controls leaf shape mediated by auxin in rice.

    Kenji Fujino;Yasuyuki Matsuda;Kenjirou Ozawa;Takeshi Nishimura

  • Monooxygenases as biocatalysts: Classification, mechanistic aspects and biotechnological applications

    D.E. Torres Pazmino;M. Winkler;A. Glieder;Marco Fraaije

  • Baeyer-Villiger monooxygenases, an emerging family of flavin-dependent biocatalysts

    NM Kamerbeek;Dick Janssen;Wjh van Berkel;Marco Fraaije

  • Enzyme-catalyzed oxidation of 5-hydroxymethylfurfural to furan-2,5-dicarboxylic acid.

    Willem P. Dijkman;Daphne E. Groothuis;Marco W. Fraaije

  • Occurrence and biocatalytic potential of carbohydrate oxidases.

    Erik W. van Hellemond;Nicole G.H. Leferink;Dominic P.H.M. Heuts;Marco W. Fraaije

  • Discovery of a thermostable Baeyer–Villiger monooxygenase by genome mining

    Marco W. Fraaije;Jin Wu;Dominic P. H. M. Heuts;Erik W. van Hellemond

  • Decorating microbes: surface display of proteins on Escherichia coli

    Edwin van Bloois;Remko T. Winter;Harald Kolmar;Marco W. Fraaije

  • Identification of a Baeyer–Villiger monooxygenase sequence motif

    Marco W. Fraaije;Nanne M. Kamerbeek;Willem J.H. van Berkel;Dick B. Janssen

  • The enigmatic reaction of flavins with oxygen

    Pimchai Chaiyen;Marco W. Fraaije;Andrea Mattevi

  • DyP‑type peroxidases: a promising and versatile class of enzymes

    Dana I. Colpa;Marco W. Fraaije;Edwin van Bloois

  • Recent Developments in the Application of Baeyer–Villiger Monooxygenases as Biocatalysts

    Gonzalo de Gonzalo;Marko D. Mihovilovic;Marco W. Fraaije

  • What's in a covalent bond? On the role and formation of covalently bound flavin cofactors.

    Dominic P. H. M. Heuts;Nigel S. Scrutton;William S. McIntire;William S. McIntire;Marco W. Fraaije

  • A robust and extracellular heme-containing peroxidase from Thermobifida fusca as prototype of a bacterial peroxidase superfamily

    Edwin van Bloois;Daniel E. Torres Pazmiño;Remko T. Winter;Marco W. Fraaije

Frequent Co-Authors

Andrea Mattevi
Andrea Mattevi University of Pavia
Willem J. H. van Berkel
Willem J. H. van Berkel Wageningen University & Research
Dick B. Janssen
Dick B. Janssen University of Groningen
Vicente Gotor
Vicente Gotor University of Oviedo
Antoine Royant
Antoine Royant Institut de Biologie Structurale
Adriaan J. Minnaard
Adriaan J. Minnaard University of Groningen
Giacomo Carrea
Giacomo Carrea National Research Council (CNR)
Jaap Visser
Jaap Visser Utrecht University
Nigel S. Scrutton
Nigel S. Scrutton University of Manchester

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying chemistry in the USA opens doors to a variety of specialized career paths, particularly in forensic sciences and related fields. For students interested in the intersection of science and law enforcement, pursuing a forensic science degree online can provide valuable practical knowledge and credentials without the need to attend on-campus classes.

Those aiming to work directly with legal investigations may consider becoming a medical examiner assistant. Detailed guidance on how to become a medical examiner assistant highlights necessary education requirements, salary expectations, and job outlooks to help prospective students make informed decisions.

Additionally, for students focused on the psychological aspects of criminal behavior, earning an online masters degree in forensic psychology offers career specialization opportunities that blend chemistry, biology, and psychology.

With forensic science being a high-demand sector, there are numerous high paying jobs in forensics available, ranging from crime lab analysts to forensic toxicologists. Exploring these online degrees and career pathways helps students align their chemistry background with in-demand forensic professions.

Best Scientists Citing Marco W. Fraaije

Trending Scientists

Recently Published Articles