Her primary scientific interests are in Biochemistry, Mitochondrion, NADH dehydrogenase, 1-Methyl-4-phenylpyridinium and Monoamine oxidase. Her work on Biochemistry deals in particular with Carnitine, Neurotoxin, NAD+ kinase, Fatty acid and Phosphatidylethanolamine. Her study on Cellular respiration and Respiratory chain is often connected to Coenzyme Q – cytochrome c reductase as part of broader study in Mitochondrion.
Her NADH dehydrogenase research incorporates themes from Rotenone and Binding site. She mostly deals with Monoamine oxidase A in her studies of Monoamine oxidase. Her Monoamine oxidase A research is multidisciplinary, relying on both Antibiotics, Docking, Stereochemistry and Monoamine oxidase B, Kynuramine.
Her primary areas of investigation include Biochemistry, Stereochemistry, Monoamine oxidase, Mitochondrion and Carnitine. Her research in Biochemistry intersects with topics in NADH dehydrogenase and Dopamine. Her NADH dehydrogenase research focuses on Rotenone and how it connects with Submitochondrial particle.
Her research integrates issues of Active site, Cofactor, Flavin group, Enzyme and Binding site in her study of Stereochemistry. Her research investigates the connection with Monoamine oxidase and areas like Pharmacology which intersect with concerns in Serotonin. Rona R. Ramsay interconnects Electron transport chain and Membrane in the investigation of issues within Mitochondrion.
Monoamine oxidase, Pharmacology, Monoamine neurotransmitter, Monoamine oxidase B and Drug are her primary areas of study. Her Monoamine oxidase study is focused on Biochemistry in general. As a part of the same scientific study, Rona R. Ramsay usually deals with the Biochemistry, concentrating on Histamine and frequently concerns with Antioxidant capacity, Receptor and Antagonism.
Her Monoamine neurotransmitter research is multidisciplinary, relying on both IC50, Docking and Disease. Her work focuses on many connections between Monoamine oxidase B and other disciplines, such as Stereochemistry, that overlap with her field of interest in Flavin group, Adduct, Binding site and Covalent bond. Her research in Drug intersects with topics in Virtual screening, Medical physics and Drug discovery.
Her primary areas of study are Pharmacology, Monoamine oxidase, Monoamine neurotransmitter, Drug discovery and Neuroscience. Her work carried out in the field of Pharmacology brings together such families of science as Acetylcholinesterase inhibitor, Monoamine oxidase B and Bioinformatics. Her work deals with themes such as Imidazoline receptor, Endogeny, Mitochondrion and Cytochrome P450, which intersect with Monoamine oxidase B.
Rona R. Ramsay frequently studies issues relating to Cholinesterase and Monoamine oxidase. Her Cholinesterase research is multidisciplinary, incorporating perspectives in Biochemistry, Disease therapy, Antagonism, Monoamine oxidase inhibitor and Histamine. Her study explores the link between Monoamine neurotransmitter and topics such as Docking that cross with problems in Monoamine oxidase A, Enzyme kinetics, Tertiary amine, Combinatorial chemistry and G protein-coupled receptor.
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Energy-dependent uptake of N-methyl-4-phenylpyridinium, the neurotoxic metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, by mitochondria.
R R Ramsay;T P Singer.
Journal of Biological Chemistry (1986)
Molecular enzymology of carnitine transfer and transport
RR Ramsay;RD Gandour;FR van der Leij.
Biochimica et Biophysica Acta (2001)
Biochemical events in the development of parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Thomas P. Singer;Neal Castagnoli;Rona R. Ramsay;Anthony J. Trevor.
Journal of Neurochemistry (1987)
Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic parkinsonism
Rona R. Ramsay;Rona R. Ramsay;James I. Salach;Jahan Dadgar;Jahan Dadgar;Thomas P. Singer;Thomas P. Singer.
Biochemical and Biophysical Research Communications (1986)
Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+.
Rona R. Ramsay;Rona R. Ramsay;James I. Salach;James I. Salach;Thomas P. Singer;Thomas P. Singer.
Biochemical and Biophysical Research Communications (1986)
Inhibition of monoamine oxidase A by beta-carboline derivatives.
Hoon Kim;Sergey O. Sablin;Sergey O. Sablin;Rona R. Ramsay;Rona R. Ramsay.
Archives of Biochemistry and Biophysics (1997)
Identification of 4-substituted 1,2,3-triazoles as novel oxazolidinone antibacterial agents with reduced activity against monoamine oxidase A.
Folkert Reck;Fei Zhou;Marc Girardot;Gunther Kern.
Journal of Medicinal Chemistry (2005)
A perspective on multi-target drug discovery and design for complex diseases
Rona R. Ramsay;Marija R. Popovic-Nikolic;Katarina Nikolic;Elisa Uliassi.
Clinical and translational medicine (2018)
Mechanism of the neurotoxicity of MPTP. An update.
Thomas P. Singer;Rona R. Ramsay;Rona R. Ramsay.
FEBS Letters (1990)
Interaction of 1-methyl-4-phenylpyridinium ion (MPP+) and its analogs with the rotenone/piericidin binding site of NADH dehydrogenase.
Rona R. Ramsay;Matthew J. Krueger;Stephen K. Youngster;Martin R. Gluck.
Journal of Neurochemistry (1991)
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