Rona R. Ramsay

Overview

Best Publications

• A perspective on multi-target drug discovery and design for complex diseases

  Rona R. Ramsay;Marija R. Popovic-Nikolic;Katarina Nikolic;Elisa Uliassi

  699
  Citations

• Energy-dependent uptake of N-methyl-4-phenylpyridinium, the neurotoxic metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, by mitochondria.

  R R Ramsay;T P Singer

  533
  Citations

• Molecular enzymology of carnitine transfer and transport

  RR Ramsay;RD Gandour;FR van der Leij

  459
  Citations

• Identification of 4-substituted 1,2,3-triazoles as novel oxazolidinone antibacterial agents with reduced activity against monoamine oxidase A.

  Folkert Reck;Fei Zhou;Marc Girardot;Gunther Kern

  360
  Citations

• Biochemical events in the development of parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

  Thomas P. Singer;Neal Castagnoli;Rona R. Ramsay;Anthony J. Trevor

  355
  Citations

• Methylene blue and serotonin toxicity: inhibition of monoamine oxidase A (MAO A) confirms a theoretical prediction

  R R Ramsay;C Dunford;P K Gillman

  324
  Citations

• Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic parkinsonism

  Rona R. Ramsay;Rona R. Ramsay;James I. Salach;Jahan Dadgar;Jahan Dadgar;Thomas P. Singer;Thomas P. Singer

  319
  Citations

• Inhibition of monoamine oxidase A by beta-carboline derivatives.

  Hoon Kim;Sergey O. Sablin;Sergey O. Sablin;Rona R. Ramsay;Rona R. Ramsay

  318
  Citations

• Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+.

  Rona R. Ramsay;Rona R. Ramsay;James I. Salach;James I. Salach;Thomas P. Singer;Thomas P. Singer

  317
  Citations

• Mechanism of the neurotoxicity of MPTP. An update.

  Thomas P. Singer;Rona R. Ramsay;Rona R. Ramsay

  267
  Citations

• Interaction of 1-methyl-4-phenylpyridinium ion (MPP+) and its analogs with the rotenone/piericidin binding site of NADH dehydrogenase.

  Rona R. Ramsay;Matthew J. Krueger;Stephen K. Youngster;Martin R. Gluck

  248
  Citations

• Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP

  Rona R. Ramsay;Jahan Dadgar;Anthony Trevor;Thomas P. Singer

  244
  Citations

• Assessment of Enzyme Inhibition: A Review with Examples from the Development of Monoamine Oxidase and Cholinesterase Inhibitory Drugs

  Rona R. Ramsay;Keith F. Tipton

  237
  Citations

• The mechanism of fatty acid uptake by heart mitochondria: an acylcarnitine-carnitine exchange.

  Rona R. Ramsay;Philip K. Tubbs

  221
  Citations

• Role of carnitine and carnitine palmitoyltransferase as integral components of the pathway for membrane phospholipid fatty acid turnover in intact human erythrocytes.

  A Arduini;G Mancinelli;G L Radatti;S Dottori

  184
  Citations

• Carnitine, mitochondrial function and therapy.

  Victor A. Zammit;Rona R. Ramsay;Mario Bonomini;Arduino Arduini

  173
  Citations

• Carnitine acyltransferases and their influence on CoA pools in health and disease.

  Rona R. Ramsay;Victor A. Zammit

  172
  Citations

• The carnitine acyltransferases and their role in modulating acyl-CoA pools.

  R. R. Ramsay;A. Arduini

  169
  Citations

• Multi-target directed donepezil-like ligands for Alzheimer's disease

  Mercedes Unzeta;Gerard Esteban;Irene Bolea;Wieslawa Agnieszka Fogel

  164
  Citations

• The inhibition site of MPP+, the neurotoxic bioactivation product of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is near the Q-binding site of NADH dehydrogenase.

  Rona R. Ramsay;Andrzej T. Kowal;Michael K. Johnson;James I. Salach

  149
  Citations