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Biology and Biochemistry

D-Index
58
Citations
9822
World Ranking
13399
National Ranking
60

Overview

Jørn A. Holme is affiliated with the Norwegian Institute of Public Health in Norway. Their research focuses primarily on environmental science and medicine, with particular attention to health, toxicology, and mutagenesis. Additional subfields of interest include pollution, molecular biology, speech and hearing, and pulmonary and respiratory medicine.

The main topics covered in their work include:

  • Air Quality and Health Impacts
  • Toxic Organic Pollutants Impact
  • Energy and Environment Impacts
  • Climate Change and Health Impacts
  • Noise Effects and Management
  • Smoking Behavior and Cessation
  • Heme Oxygenase-1 and Carbon Monoxide

Holme has authored and co-authored several scientific papers addressing various aspects of environmental toxicology and respiratory health. Notable recent publications include:

  • "Potential role of polycyclic aromatic hydrocarbons in air pollution-induced non-malignant respiratory diseases," 2020, Respiratory Research
  • "Lung cancer associated with combustion particles and fine particulate matter (PM2.5) - The roles of polycyclic aromatic hydrocarbons (PAHs) and the aryl hydrocarbon receptor (AhR)," 2023, Biochemical Pharmacology
  • "Pro-inflammatory effects of crystalline- and nano-sized non-crystalline silica particles in a 3D alveolar model," 2020, Particle and Fibre Toxicology
  • "Characterization and pro-inflammatory potential of indoor mold particles," 2020, Indoor Air
  • "A systematic review of cancer risk among users of smokeless tobacco (Swedish snus) exclusively, compared with no use of tobacco," 2023, International Journal of Cancer

Their frequent coauthors include:

  • Johan Øvrevik
  • Marit Låg
  • Magne Refsnes
  • Tonje Skuland
  • Bendik C. Brinchmann

Holme's work has been published in journals with a focus on toxicology and respiratory research. Common publication venues consist of:

  • Particle and Fibre Toxicology
  • Toxicology
  • Toxicology in Vitro
  • Respiratory Research
  • Biochemical Pharmacology

Best Publications

  • Phthalate levels in Norwegian indoor air related to particle size fraction

    Kirsten Eline Rakkestad;Christian Jarle Dye;Karl Espen Yttri;Jørn Andreas Holme

  • Recent Advances in Particulate Matter and Nanoparticle Toxicology: A Review of the In Vivo and In Vitro Studies

    Abderrahim Nemmar;Jørn Andreas Holme;Irma Rosas;Per E Schwarze

  • Activation of Proinflammatory Responses in Cells of the Airway Mucosa by Particulate Matter: Oxidant- and Non-Oxidant-Mediated Triggering Mechanisms

    Johan Øvrevik;Magne Refsnes;Marit Låg;Jørn A. Holme

  • Differences in cytotoxicity versus pro-inflammatory potency of different PM fractions in human epithelial lung cells.

    Maurizio Gualtieri;J. Øvrevik;J.A. Holme;M.G. Perrone

  • Cell cycle alterations induced by urban PM2.5 in bronchial epithelial cells: Characterization of the process and possible mechanisms involved

    Eleonora Longhin;Jørn Andreas Holme;Kristine Bjerve Gutzkow;Volker Arlt

  • Airborne urban particles (Milan winter-PM2.5) cause mitotic arrest and cell death: Effects on DNA, mitochondria, AhR binding and spindle organization

    Maurizio Gualtieri;Johan Øvrevik;Steen Mollerup;Nana Asare

  • Effects of the Environmental Oestrogens Bisphenol A, Tetrachlorobisphenol A, Tetrabromobisphenol A, 4‐Hydroxybiphenyl and 4,4′‐Dihydroxybiphenyl on Oestrogen Receptor Binding, Cell Proliferation and Regulation of Oestrogen Sensitive Proteins in the Human Breast Cancer Cell Line MCF‐7

    Christel M Olsen;Elise T M Meussen-Elholm;Mari Samuelsen;Jørn A Holme

  • Comparison of non-crystalline silica nanoparticles in IL-1β release from macrophages

    Wiggo J Sandberg;Marit Låg;Jørn A Holme;Bernd Friede

  • Polycyclic aromatic hydrocarbons induce both apoptotic and anti-apoptotic signals in Hepa1c1c7 cells.

    Anita Solhaug;Magne Refsnes;Marit Låg;Per E. Schwarze

  • Differential effects of nitro-PAHs and amino-PAHs on cytokine and chemokine responses in human bronchial epithelial BEAS-2B cells

    J Ovrevik;Volker Arlt;E Oya;Eszter Nagy

  • Mechanism of paracetamol toxicity

    Jørn A. Holme;Dag Jacobsen

  • Cytotoxic effects of N-acetyl-p-benzoquinone imine, a common arylating intermediate of paracetamol and N-hydroxyparacetamol.

    Jørn A. Holme;David C. Dahlin;Sidney D. Nelson;Erik Dybing

  • Effect of n-3 and n-6 fatty acids on proliferation and differentiation of promyelocytic leukemic HL-60 cells.

    Hanne S. Finstad;Svein O. Kolset;Jtfrn A. Holme;Richard Wiger

  • Potential role of polycyclic aromatic hydrocarbons as mediators of cardiovascular effects from combustion particles.

    Jørn Andreas Holme;Bendik Christian Brinchmann;Magne Arnold Refsnes;Marit Låg

  • Effects of nitrated-polycyclic aromatic hydrocarbons and diesel exhaust particle extracts on cell signalling related to apoptosis: Possible implications for their mutagenic and carcinogenic effects

    Nina E Landvik;Morgane Gorria;Volker M Arlt;Nana Asare

  • Potential role of polycyclic aromatic hydrocarbons in air pollution-induced non-malignant respiratory diseases

    Marit Låg;Johan Øvrevik;Johan Øvrevik;Magne Arnold Refsnes;Jørn Andreas Holme

  • Cytokine and chemokine expression patterns in lung epithelial cells exposed to components characteristic of particulate air pollution

    J. Øvrevik;M. Låg;J.A. Holme;P.E. Schwarze

  • Genotoxicity of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): formation of 2-hydroxamino-PhIP, a directly acting genotoxic metabolite.

    Jørn A. Holme;Hàkan Wallin;Gunnar Brunborg;Erik J. Søderlund

  • Estrogen-like properties of brominated analogs of bisphenol A in the MCF-7 human breast cancer cell line.

    M Samuelsen;C Olsen;J A Holme;E Meussen-Elholm

  • Highly efficient base excision repair (BER) in human and rat male germ cells.

    Ann-Karin Olsen;Helle Bjørtuft;Richard Wiger;Jørn A. Holme

Frequent Co-Authors

Gunnar Brunborg
Gunnar Brunborg Norwegian Institute of Public Health
Per E. Schwarze
Per E. Schwarze Norwegian Institute of Public Health
Sidney D. Nelson
Sidney D. Nelson University of Washington
Jan Alexander
Jan Alexander Norwegian Institute of Public Health
Georg Becher
Georg Becher University of Oslo
Volker M. Arlt
Volker M. Arlt King's College London
Olivier Fardel
Olivier Fardel University of Rennes
Håkan Wallin
Håkan Wallin National Institute of Occupational Health
Snorri S. Thorgeirsson
Snorri S. Thorgeirsson National Institutes of Health
David H. Phillips
David H. Phillips King's College London

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