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Ada M. Kruisbeek

Ada M. Kruisbeek

D-Index & Metrics

Microbiology

D-Index
63
Citations
13526
World Ranking
2745
National Ranking
110

Research.com Recognitions

  • 2000 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Ada M. Kruisbeek is affiliated with DCprime in the Netherlands and has a research focus spanning immunology, microbiology, biochemistry, genetics, and molecular biology. Their work primarily addresses immunotherapy, immune responses, RNA interference, gene delivery, and CAR-T cell therapy research. These topics reflect a concentration on immune cell function, interaction, and oncological processes.

Their recent publications include studies centered on the dynamics between cell-based cancer vaccines and host immune cells. In 2021, they contributed to research published in Cells titled "Transfer of Cellular Content from the Allogeneic Cell-Based Cancer Vaccine DCP-001 to Host Dendritic Cells Hinges on Phosphatidylserine and Is Enhanced by CD47 Blockade." The same year, they co-authored work published in Regular and Young Investigator Award Abstracts on the role of CD47 and phosphatidylserine in interactions between antigen presenting cells and the allogeneic cell-based relapse vaccine DCP-001.

Frequent co-authors who have collaborated with Ada M. Kruisbeek include Satwinder Singh, Haoxiao Zuo, Jorn Kaspers, Remco Bos, and Alwin Kamermans.

Their frequent publication venues are the journal Cells and the Regular and Young Investigator Award Abstracts conference series. Fields of study connected to their research include:

  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

Within these domains, the subfields prominently represented are:

  • Immunology
  • Molecular Biology
  • Oncology

Main topics covered in their research are:

  • Immunotherapy and Immune Responses
  • RNA Interference and Gene Delivery
  • CAR-T cell therapy research
  • Immune Cell Function and Interaction

Ada M. Kruisbeek has been recognized by membership in prestigious organizations, including becoming a Member of Academia Europaea in 2000 and membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells

    Willem W. Overwijk;Marc R. Theoret;Steven E. Finkelstein;Deborah R. Surman

  • E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

    Gretchen Bain;Els C.Robanus Maandag;David J. Izon;Derk Amsen

  • Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4

    M W Schilham;M A Oosterwegel;P Moerer;J Ya

  • A novel population of T-cell receptor alpha beta-bearing thymocytes which predominantly expresses a single V beta gene family.

    B. J. Fowlkes;A. M. Kruisbeek;H. Ton-That;M. A. Weston

  • In vivo induction of anergy in peripheral V beta 8+ T cells by staphylococcal enterotoxin B.

    B L Rellahan;L A Jones;A M Kruisbeek;A M Fry

  • Differential expression of two distinct T-cell receptors during thymocyte development.

    Drew M. Pardoll;B. J. Fowlkes;Jeffrey A. Bluestone;Ada Kruisbeek

  • Differential expression of the HMG box factors TCF-1 and LEF-1 during murine embryogenesis.

    M. Oosterwegel;M. van de Wetering;J. Timmerman;A. Kruisbeek

  • C-type lectin-like molecule-1: A novel myeloid cell surface marker associated with acute myeloid leukemia

    Alexander B. H. Bakker;Sonja van den Oudenrijn;Arjen Q. Bakker;Nicole Feller

  • Peripheral clonal elimination of functional T cells

    LA Jones;LT Chin;DL Longo;AM Kruisbeek

  • Absence of the Lyt-2-,L3T4+ lineage of T cells in mice treated neonatally with anti-I-A correlates with absence of intrathymic I-A-bearing antigen-presenting cell function.

    A M Kruisbeek;J J Mond;B J Fowlkes;J A Carmen

  • Characterization of T cell receptor gamma chain expression in a subset of murine thymocytes.

    A. M. Lew;D. M. Pardoll;W. L. Maloy;B. J. Fowlkes

  • Selective Expansion of Cross-Reactive Cd8+ Memory T Cells by Viral Variants

    John B.A.G. Haanen;Monika C. Wolkers;Ada M. Kruisbeek;Ton N.M. Schumacher

  • Cytotoxic T Lymphocyte Antigen 4 (CTLA-4) Interferes with Extracellular Signal-regulated Kinase (ERK) and Jun NH2-terminal Kinase (JNK) Activation, but Does Not Affect Phosphorylation of T Cell Receptor ζ and ZAP70

    Concepcion Revilla Calvo;Derk Amsen;Ada M. Kruisbeek

  • The CD3γ chain is essential for development of both the TCRαβ and TCRγδ lineages

    Mariëlle C. Haks;Paul Krimpenfort;Jannie Borst;Ada M. Kruisbeek

  • Limited diversity of T-cell receptor gamma-chain expression of murine Thy-1+ dendritic epidermal cells revealed by V gamma 3-specific monoclonal antibody

    Wendy L. Havran;Stanley Grell;Gail Duwe;John Kimura

  • Engagement of CD4 and CD8 expressed on immature thymocytes induces activation of intracellular tyrosine phosphorylation pathways

    A Veillette;J C Zúñiga-Pflücker;J B Bolen;A M Kruisbeek

  • Proliferative assays for T cell function.

    Ada M. Kruisbeek;Ethan Shevach;Angela M. Thornton

  • Pre-TCR signaling and inactivation of p53 induces crucial cell survival pathways in pre-T cells

    Mariëlle C Haks;Paul Krimpenfort;Jeroen H.N van den Brakel;Ada M Kruisbeek

  • Induction of TCR Gene Rearrangements in Uncommitted Stem Cells by a Subset of IL-7 Producing, MHC Class II–Expressing Thymic Stromal Cells

    Mariëtte A Oosterwegel;Marille C Haks;Ursula Jeffry;Richard Murray

  • Branching out to gain control: how the pre-TCR is linked to multiple functions

    Ada M Kruisbeek;Mariëlle C Haks;Michael Carleton;David L Wiest

  • Peptide-Induced Negative Selection of Thymocytes Activates Transcription of an NF-ΚB Inhibitor

    Emma Fiorini;Ingo Schmitz;Wilfred E. Marissen;Stephanie L. Osborn

Frequent Co-Authors

Dan L. Longo
Dan L. Longo Harvard University
Juan Carlos Zúñiga-Pflücker
Juan Carlos Zúñiga-Pflücker University of Toronto
Ton N. M. Schumacher
Ton N. M. Schumacher Antoni van Leeuwenhoek Hospital
Alfred Singer
Alfred Singer National Institutes of Health
John E. Coligan
John E. Coligan National Institutes of Health
Susan O. Sharrow
Susan O. Sharrow National Institutes of Health
Ronald H. Schwartz
Ronald H. Schwartz National Institutes of Health
Tanja D. de Gruijl
Tanja D. de Gruijl Vrije Universiteit Amsterdam
B. J. Fowlkes
B. J. Fowlkes National Institutes of Health
John B. A. G. Haanen
John B. A. G. Haanen Antoni van Leeuwenhoek Hospital

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