World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
70
Citations
17268
World Ranking
2421
National Ranking
1160

Overview

Susan O. Sharrow is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on immunology, with specific attention to subfields within immunology that cover T-cell and B-cell immunology, immune cell function and interaction, and immunotherapy and immune responses.

The main topics of their work include:

  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses

Sharrow has contributed to the field through publications in notable venues. Their frequent publication venue is Nature Immunology, reflecting engagement with high-impact research communities in immunology and microbiology.

One of their recent papers is titled "How autoreactive thymocytes differentiate into regulatory versus effector CD4+ T cells after avoiding clonal deletion," published in 2023 in Nature Immunology.

Frequent collaborators in Sharrow's research include:

  • Xuguang Tai
  • Alyssa Indart
  • Mirelle Rojano
  • Jie Guo
  • Nicolai Apenes

Their work sits at the intersection of immunology and microbiology, emphasizing the cellular and molecular mechanisms that govern immune system regulation, particularly relating to T cells. The published research addresses the differentiation pathways of autoreactive thymocytes, investigating how these cells avoid clonal deletion and instead develop into regulatory or effector T cells, which are critical processes for immune tolerance and response.

Susan O. Sharrow's contributions align with ongoing scientific efforts to better understand immune cell dynamics and the mechanisms underpinning immune responses and therapies, as indicated by their specialization in immunotherapy and immune responses in addition to fundamental immunological functions.

Best Publications

  • Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production.

    M E Sanders;M W Makgoba;S O Sharrow;D Stephany

  • In vivo administration of purified human interleukin 2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2.

    M. T. Lotze;Y. L. Matory;S. E. Ettinghausen;A. A. Rayner

  • Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins.

    S J Korsmeyer;A Arnold;A Bakhshi;J V Ravetch

  • Expression of interleukin 2 receptors on activated human B cells.

    Thomas A. Waldmann;Carolyn K. Goldman;Richard J. Robb;Joel M. Depper

  • Determination of surface antigens on highly purified human NK cells by flow cytometry with monoclonal antibodies.

    J R Ortaldo;S O Sharrow;T Timonen;R B Herberman

  • In vivo administration of purified human interleukin 2. I. Half-life and immunologic effects of the Jurkat cell line-derived interleukin 2

    M T Lotze;L W Frana;S O Sharrow;R J Robb

  • Thymic-independent T cell regeneration occurs via antigen-driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing.

    Crystal L. Mackall;Catherine V. Bare;Larry A. Granger;Susan O. Sharrow

  • Texas red, a hydrophilic, red-emitting flourophore for use with flourescein in dual parameter flow microfluorometric and fluorescence microscopic studies

    Julie A. Titus;Richard Haugland;Susan O. Sharrow;David M. Segal

  • Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28

    J A Punt;B A Osborne;Y Takahama;S O Sharrow

  • Coreceptor Reversal in the Thymus: Signaled CD4+8+ Thymocytes Initially Terminate CD8 Transcription Even When Differentiating into CD8+ T Cells

    Enrico Brugnera;Avinash Bhandoola;Ricardo Cibotti;Qing Yu

  • Characterization of murine thymocytes with CDS-associated T-cell receptor structures

    Jeffrey A. Bluestone;Drew Pardoll;Susan O. Sharrow;B. J. Fowlkes

  • Functional and phenotypic comparison of human T cell leukemia/lymphoma virus positive adult T cell leukemia with human T cell leukemia/lymphoma virus negative Sézary leukemia, and their distinction using anti-Tac. Monoclonal antibody identifying the human receptor for T cell growth factor.

    T A Waldmann;W C Greene;P S Sarin;C Saxinger

  • Basis of CTLA-4 function in regulatory and conventional CD4+ T cells

    Xuguang Tai;François Van Laethem;Leonid Pobezinsky;Terry Guinter

  • B-lymphocyte heterogeneity: development and characterization of an alloantiserum which distinguishes B-lymphocyte differentiation alloantigens.

    Aftab Ahmed;Irwin Scher;Susan O Sharrow;Allan H Smith

  • Cell cycle of Saccharomycescerevisiae in populations growing at different rates

    Martin L. Slater;Susan O. Sharrow;John J. Gart

  • Phenotype, specificity, and function of T cell subsets and T cell interactions involved in skin allograft rejection.

    A S Rosenberg;T Mizuochi;S O Sharrow;A Singer

  • Role of cytotoxic T lymphocytes in the prevention of lupus-like disease occurring in a murine model of graft-vs-host disease.

    C S Via;S O Sharrow;G M Shearer

  • Therapy of patients with human T-cell lymphotrophic virus I-induced adult T-cell leukemia with anti-Tac, a monoclonal antibody to the receptor for interleukin-2

    Thomas A. Waldmann;Carolyn K. Goldman;Kathleen F. Bongiovanni;Susan O. Sharrow

  • Deletion of CD4 and CD8 Coreceptors Permits Generation of αβT Cells that Recognize Antigens Independently of the MHC

    François Van Laethem;Sophia D. Sarafova;Jung-Hyun Park;Xuguang Tai

  • DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier

    Margarida A. Santos;Robert B. Faryabi;Aysegul V. Ergen;Amanda M. Day

  • Enhanced antigen-presenting capacity of cultured Langerhans' cells is associated with markedly increased expression of Ia antigen.

    S Shimada;S W Caughman;S O Sharrow;D Stephany

Frequent Co-Authors

Alfred Singer
Alfred Singer National Institutes of Health
David H. Sachs
David H. Sachs Columbia University
Richard J. Hodes
Richard J. Hodes National Institutes of Health
Yousuke Takahama
Yousuke Takahama National Institutes of Health
William E. Paul
William E. Paul National Institute of Allergy and Infectious Diseases
Gene M. Shearer
Gene M. Shearer National Institutes of Health
Carolyn K. Goldman
Carolyn K. Goldman National Institutes of Health
Thomas A. Waldmann
Thomas A. Waldmann National Institutes of Health
Irwin Scher
Irwin Scher OperTechBio

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those interested in immunology, related health science degrees can open doors to diverse career paths. Accelerated nursing programs are a popular choice for students seeking fast-track entry into healthcare. If you want to ease into nursing, consider exploring absn programs with high acceptance rates, which provide efficient pathways with greater accessibility.

Many students also opt for licensure as a practical nurse, finding accredited lpn programs easy to get into. These programs typically have flexible online options, ideal for balancing study with other commitments.

For advanced practice, nurse practitioner degrees are a strong step forward. Among the options, understanding which nurse practitioner program is easiest can help you identify programs that fit your academic strengths and career goals.

Specifically, psychiatric-mental health nurse practitioner credentials are in high demand. The best online pmhnp programs offer strong clinical placements, enabling practical experience essential for success in specialized healthcare roles.

Best Scientists Citing Susan O. Sharrow

Trending Scientists

Recently Published Articles