D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 69 Citations 16,336 163 World Ranking 1637 National Ranking 813

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Immune system
  • Antibody

Her primary areas of investigation include Immunology, T cell, Molecular biology, Antigen and Cytotoxic T cell. Her Immunology study frequently intersects with other fields, such as Cell biology. In her work, T-cell leukemia is strongly intertwined with Antibody, which is a subfield of T cell.

Her research in Molecular biology intersects with topics in Surface Immunoglobulin, B cell, Receptor, Immunoglobulin M and Lymphocyte. The various areas that Susan O. Sharrow examines in her Cytotoxic T cell study include Jurkat cells, Immune system, Immunoglobulin D, C57BL/6 and Spleen. Her work deals with themes such as Endocrinology and Lymphokine, which intersect with Interleukin 2.

Her most cited work include:

  • Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production. (818 citations)
  • Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins. (533 citations)
  • In vivo administration of purified human interleukin 2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2. (520 citations)

What are the main themes of her work throughout her whole career to date?

Susan O. Sharrow mainly focuses on Molecular biology, Immunology, Antigen, T cell and CD8. Her Molecular biology study combines topics from a wide range of disciplines, such as Cell, Receptor, Spleen and Antibody, Monoclonal antibody. Her research in Immunology focuses on subjects like Cytotoxic T cell, which are connected to Transcription.

She studied Antigen and Lymphocyte that intersect with Surface Immunoglobulin. Her work on Antigen-presenting cell as part of general T cell study is frequently linked to Population, therefore connecting diverse disciplines of science. Her CD8 research incorporates elements of Cell biology, Cellular differentiation and T-cell receptor.

She most often published in these fields:

  • Molecular biology (49.10%)
  • Immunology (39.52%)
  • Antigen (35.33%)

What were the highlights of her more recent work (between 1998-2017)?

  • CD8 (23.95%)
  • Cell biology (20.36%)
  • T-cell receptor (18.56%)

In recent papers she was focusing on the following fields of study:

Her primary areas of study are CD8, Cell biology, T-cell receptor, T cell and Signal transduction. Her CD8 study combines topics in areas such as Cytotoxic T cell, Receptor, Transcription and Molecular biology. Her research integrates issues of Double negative and Biochemistry in her study of Molecular biology.

Her Cell biology research includes elements of Superantigen, Thymocyte, CD40, Immunology and Negative selection. Her T-cell receptor research incorporates themes from Major histocompatibility complex and Transgene. Her work in the fields of T cell, such as MHC class II, overlaps with other areas such as Population.

Between 1998 and 2017, her most popular works were:

  • Coreceptor Reversal in the Thymus: Signaled CD4+8+ Thymocytes Initially Terminate CD8 Transcription Even When Differentiating into CD8+ T Cells (229 citations)
  • Basis of CTLA-4 function in regulatory and conventional CD4(+) T cells. (160 citations)
  • Deletion of CD4 and CD8 Coreceptors Permits Generation of αβT Cells that Recognize Antigens Independently of the MHC (144 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Antibody

Her main research concerns T-cell receptor, Signal transduction, Immunology, CD8 and Cell biology. Her T-cell receptor research is multidisciplinary, incorporating perspectives in Tyrosine kinase and Major histocompatibility complex, Antigen. Her Immunology study frequently draws connections to adjacent fields such as Gene rearrangement.

Her CD8 research includes themes of Cytotoxic T cell and T cell. Within one scientific family, Susan O. Sharrow focuses on topics pertaining to Receptor under Cytotoxic T cell, and may sometimes address concerns connected to Molecular biology and Thymocyte. Her Molecular biology research focuses on subjects like In vivo, which are linked to Internal medicine and Endocrinology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production.

M E Sanders;M W Makgoba;S O Sharrow;D Stephany.
Journal of Immunology (1988)

1328 Citations

In vivo administration of purified human interleukin 2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2.

M. T. Lotze;Y. L. Matory;S. E. Ettinghausen;A. A. Rayner.
Journal of Immunology (1985)

817 Citations

Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins.

S J Korsmeyer;A Arnold;A Bakhshi;J V Ravetch.
Journal of Clinical Investigation (1983)

668 Citations

Expression of interleukin 2 receptors on activated human B cells.

Thomas A. Waldmann;Carolyn K. Goldman;Richard J. Robb;Joel M. Depper.
Journal of Experimental Medicine (1984)

621 Citations

Determination of surface antigens on highly purified human NK cells by flow cytometry with monoclonal antibodies.

J R Ortaldo;S O Sharrow;T Timonen;R B Herberman.
Journal of Immunology (1981)

516 Citations

Thymic-independent T cell regeneration occurs via antigen-driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing.

Crystal L. Mackall;Catherine V. Bare;Larry A. Granger;Susan O. Sharrow.
Journal of Immunology (1996)

471 Citations

In vivo administration of purified human interleukin 2. I. Half-life and immunologic effects of the Jurkat cell line-derived interleukin 2

M T Lotze;L W Frana;S O Sharrow;R J Robb.
Journal of Immunology (1985)

465 Citations

Texas red, a hydrophilic, red-emitting flourophore for use with flourescein in dual parameter flow microfluorometric and fluorescence microscopic studies

Julie A. Titus;Richard Haugland;Susan O. Sharrow;David M. Segal.
Journal of Immunological Methods (1982)

427 Citations

Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28

J A Punt;B A Osborne;Y Takahama;S O Sharrow.
Journal of Experimental Medicine (1994)

350 Citations

Coreceptor Reversal in the Thymus: Signaled CD4+8+ Thymocytes Initially Terminate CD8 Transcription Even When Differentiating into CD8+ T Cells

Enrico Brugnera;Avinash Bhandoola;Ricardo Cibotti;Qing Yu.
Immunity (2000)

338 Citations

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