World's Best Scientists 2026 revealed!
Bruce Tidor

Bruce Tidor

D-Index & Metrics

Chemistry

D-Index
60
Citations
23038
World Ranking
9525
National Ranking
2673

Research.com Recognitions

  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1999 - Fellow of Alfred P. Sloan Foundation

Overview

Bruce Tidor is affiliated with MIT in the United States and has a research focus within the field of Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Molecular Biology, Spectroscopy, and Computational Theory and Mathematics.

Their research addresses a range of topics such as:

  • Microbial Metabolic Engineering and Bioproduction
  • Enzyme Catalysis and Immobilization
  • Protein Structure and Dynamics
  • Advanced biosensing and bioanalysis techniques
  • RNA modifications and cancer
  • DNA and Nucleic Acid Chemistry
  • Molecular spectroscopy and chirality

Recent publications by Bruce Tidor include:

  • "Substrate Turnover Dynamics Guide Ketol-Acid Reductoisomerase Redesign for Increased Specific Activity," 2024, ACS Catalysis
  • "Using turnover dynamics to redesign KARI for improved catalytic activity," 2023, Biophysical Journal
  • "Modelling the impact of nucleolin expression level on the activity of F3 peptide-targeted pH-sensitive pegylated liposomes containing doxorubicin," 2021, Drug Delivery and Translational Research
  • "Entropy of Two-Molecule Correlated Translational-Rotational Motions Using the kth Nearest Neighbor Method," 2021, Journal of Chemical Theory and Computation
  • "Series Foreword," 2020, Contraception

Bruce Tidor has collaborated with several researchers, including:

  • Elijah Karvelis
  • Chloe Swanson
  • Rui M. Lopes
  • Kevin Shi
  • Nuno A. Fonseca

The venues that frequently publish Bruce Tidor's research work include:

  • ACS Catalysis
  • Drug Delivery and Translational Research
  • Journal of Chemical Theory and Computation
  • Contraception
  • Biophysical Journal

Over the course of their career, Bruce Tidor has received recognitions such as:

  • Fellow of the American Association for the Advancement of Science (AAAS), 2009
  • Fellow of Alfred P. Sloan Foundation, 1999

Best Publications

  • CHARMM: the biomolecular simulation program.

    B. R. Brooks;C. L. Brooks;A. D. Mackerell;L. Nilsson

  • Arginine-mediated RNA recognition: the arginine fork.

    Barbara J. Calnan;Bruce Tidor;Sara Biancalana;Derek Hudson

  • Do salt bridges stabilize proteins? A continuum electrostatic analysis

    Zachary S. Hendsch;Bruce Tidor

  • High-Resolution Protein Design with Backbone Freedom

    Pehr B. Harbury;Joseph J. Plecs;Bruce Tidor;Tom Alber

  • Structural model for the β-amyloid fibril based on interstrand alignment of an antiparallel-sheet comprising a C-terminal peptide

    Lansbury Pt;Costa Pr;Griffiths Jm;Simon Ej;Simon Ej

  • Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control

    Effendi Leonard;Parayil Kumaran Ajikumar;Kelly Thayer;Wen-Hai Xiao

  • Computational design of antibody-affinity improvement beyond in vivo maturation

    Shaun M Lippow;K Dane Wittrup;Bruce Tidor

  • Rational Approaches to Improving Selectivity in Drug Design

    David J. Huggins;Woody Sherman;Bruce Tidor

  • The contribution of vibrational entropy to molecular association. The dimerization of insulin.

    Bruce Tidor;Martin Karplus

  • Hidden thermodynamics of mutant proteins: a molecular dynamics analysis.

    Jiali Gao;Krzysztof Kuczera;Bruce Tidor;Martin Karplus

  • De novo determination of peptide structure with solid-state magic-angle spinning NMR spectroscopy.

    Chad M. Rienstra;Lisa Tucker-Kellogg;Christopher P. Jaroniec;Morten Hohwy

  • Rational modification of protein stability by the mutation of charged surface residues.

    Shari Spector;Minghui Wang;Stefan A. Carp;James Robblee

  • Progress in computational protein design

    Shaun M. Lippow;Bruce Tidor

  • Dynamics of DNA oligomers.

    Bruce Tidor;Karl K. Irikura;Bernard R. Brooks;Martin Karplus

  • Repacking protein cores with backbone freedom: structure prediction for coiled coils

    Pehr B. Harbury;Bruce Tidor;Peter S. Kim

  • Aglycosylated immunoglobulin G1 variants productively engage activating Fc receptors

    Stephen L. Sazinsky;René G. Ott;Nathaniel W. Silver;Bruce Tidor

  • Simulation analysis of the stability mutant R96H of T4 lysozyme.

    Bruce Tidor;Martin Karplus

  • Rational cytokine design for increased lifetime and enhanced potency using pH-activated "histidine switching".

    Casim A. Sarkar;Ky Lowenhaupt;Thomas Horan;Thomas C. Boone

  • Solvent effect on the anomeric equilibrium in D-glucose: a free energy simulation analysis

    Sookhee Ha;Jiali Gao;Bruce Tidor;John W. Brady

  • Optimization of binding electrostatics: Charge complementarity in the barnase‐barstar protein complex

    Lee-Peng lee;Bruce Tidor

  • Molecular dynamics simulations

    Bruce Tidor

Frequent Co-Authors

Martin Karplus
Martin Karplus Harvard University
Celia A. Schiffer
Celia A. Schiffer University of Massachusetts Chan Medical School
Tariq M. Rana
Tariq M. Rana University of California, San Diego
Michael K. Gilson
Michael K. Gilson University of California, San Diego
Eugénio C. Ferreira
Eugénio C. Ferreira University of Minho

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