Philippe Lettéron

Overview

Best Publications

• Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis

  Gabriel Perlemuter;Abdelmajid Sabile;Philippe Letteron;Giovanna Vona

  763
  Citations

• Steatohepatitis-inducing drugs cause mitochondrial dysfunction and lipid peroxidation in rat hepatocytes.

  Alain Berson;Virginie De Beco;Philippe Lettéron;Marie Anne Robin

  522
  Citations

• Acute and chronic hepatic steatosis lead to in vivo lipid peroxidation in mice

  Philippe Lettéron;Bernard Fromenty;Terris Benoît;Claude Degott

  382
  Citations

• Mechanism for the protective effects of silymarin against carbon tetrachloride-induced lipid peroxidation and hepatotoxicity in mice. Evidence that silymarin acts both as an inhibitor of metabolic activation and as a chain-breaking antioxidant.

  Philippe Lettéron;Gilles Labbe;Claude Degott;Alain Berson

  335
  Citations

• Central role of mitochondria in drug-induced liver injury

  Dominique Pessayre;Bernard Fromenty;Alain Berson;Marie-Anne Robin

  296
  Citations

• Intestinal DMT1 cotransporter is down-regulated by hepcidin via proteasome internalization and degradation.

  Carole Brasse–Lagnel;Carole Brasse–Lagnel;Zoubida Karim;Philippe Letteron;Soumeya Bekri

  268
  Citations

• An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in mice

  Abdellah Mansouri;Isabelle Gaou;Caroline de Kerguenec;Sabine Amsellem

  265
  Citations

• Inhibition of microsomal triglyceride transfer protein: Another mechanism for drug‐induced steatosis in mice

  Philippe Lettéron;Angela Sutton;Abdellah Mansouri;Bernard Fromenty

  243
  Citations

• Amiodarone inhibits the mitochondrial beta-oxidation of fatty acids and produces microvesicular steatosis of the liver in mice.

  B Fromenty;C Fisch;G Labbe;C Degott

  236
  Citations

• Dual effect of amiodarone on mitochondrial respiration. Initial protonophoric uncoupling effect followed by inhibition of the respiratory chain at the levels of complex I and complex II.

  B Fromenty;C Fisch;A Berson;P Letteron

  217
  Citations

• Mucosal-associated invariant T cells are a profibrogenic immune cell population in the liver

  Pushpa Hegde;Pushpa Hegde;Emmanuel Weiss;Emmanuel Weiss;Valérie Paradis;Valérie Paradis;Jinghong Wan;Jinghong Wan

  201
  Citations

• Impaired adaptive resynthesis and prolonged depletion of hepatic mitochondrial DNA after repeated alcohol binges in mice.

  Christine Demeilliers;Caroline Maisonneuve;Alain Grodet;Abdellah Mansouri

  191
  Citations

• Inhibition of the mitochondrial oxidation of fatty acids by tetracycline in mice and in man: possible role in microvesicular steatosis induced by this antibiotic.

  Eric Fréneaux;Gilles Labbe;Philippe Letteron

  186
  Citations

• Perinatal undernutrition affects the methylation and expression of the leptin gene in adults: implication for the understanding of metabolic syndrome

  Céline Jousse;Céline Jousse;Laurent Parry;Sarah Lambert-Langlais;Anne-Catherine Maurin

  176
  Citations

• Toxicity of the antiandrogen flutamide in isolated rat hepatocytes.

  D Fau;D Eugene;A Berson;P Letteron

  175
  Citations

• Tamoxifen Inhibits Topoisomerases, Depletes Mitochondrial DNA, and Triggers Steatosis in Mouse Liver

  Isabelle Larosche;Philippe Lettéron;Bernard Fromenty;Nathalie Vadrot

  171
  Citations

• Punicic Acid a Conjugated Linolenic Acid Inhibits TNFα-Induced Neutrophil Hyperactivation and Protects from Experimental Colon Inflammation in Rats

  Tarek Boussetta;Houssam Raad;Philippe Lettéron;Marie-Anne Gougerot-Pocidalo

  163
  Citations

• Hepatotoxicity of germander in mice.

  Jacqueline Loeper;Veronique Descatoire;Philippe Letteron;Claude Moulis

  155
  Citations

• Cytochrome P450–generated reactive metabolites cause mitochondrial permeability transition, caspase activation, and apoptosis in rat hepatocytes

  Delphine Haouzi;Mounia Lekéhal;Alain Moreau;Claude Moulis

  139
  Citations

• Increased ethane exhalation, an in vivo index of lipid peroxidation, in alcohol-abusers.

  P Lettéron;V Duchatelle;A Berson;B Fromenty

  137
  Citations