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D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
14245
World Ranking
13046
National Ranking
928

Overview

Nicholas S. Foulkes is a researcher affiliated with the Karlsruhe Institute of Technology in Germany. Their work spans multiple disciplines, including biochemistry, genetics, molecular biology, neuroscience, and environmental science, with a considerable focus on intersecting subfields such as molecular biology, endocrine and autonomic systems, ecology, physiology, and cell biology.

The core research topics addressed by Foulkes encompass circadian rhythm and melatonin, zebrafish biomedical research applications, photoreceptor and optogenetics research, neuroinflammation and neurodegeneration mechanisms, physiological and biochemical adaptations, animal behavior and reproduction, and fish ecology and management studies.

Foulkes has contributed to scientific journals with recent publications that include:

  • Reactive Oxygen Species Signaling and Oxidative Stress: Transcriptional Regulation and Evolution (2024) - Antioxidants
  • Early-life lead exposure induces long-term toxicity in the central nervous system: From zebrafish larvae to juveniles and adults (2021) - The Science of The Total Environment
  • Photoreceptor Diversification Accompanies the Evolution of Anthozoa (2020) - Molecular Biology and Evolution
  • Ferroptosis contributes to nickel-induced developmental neurotoxicity in zebrafish (2022) - The Science of The Total Environment
  • Comparison of anxiety-like and social behaviour in medaka and zebrafish (2022) - Scientific Reports

Frequent coauthors who have collaborated with Foulkes include Daniela Vallone, Haiyu Zhao, Cristiano Bertolucci, Shengxiang Zhang, and Zuo Wang. These collaborations indicate multi-disciplinary and international research efforts.

Foulkes's work is published notably in the following venues:

  • Scientific Reports
  • The Science of The Total Environment
  • PLoS Genetics
  • Antioxidants
  • iScience

The distribution of Foulkes's research topics and publications reflects an integrative approach to both fundamental and applied biological sciences, particularly utilizing zebrafish models for biomedical research and environmental toxicology studies. The range of topics also highlights an interest in molecular and physiological mechanisms underlying development, behavior, and environmental interactions.

Best Publications

  • CREM gene: use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription.

    Nicholas S. Foulkes;Emiliana Borrelli;Paolo Sassone-Corsi

  • Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor.

    Carlos A. Molina;Nicholas S. Foulkes;Enzo Lalli;Paolo Sassone-Corsi

  • Spermiogenesis deficiency and germ-cell apoptosis in CREM-mutant mice

    François Nantel;Lucia Monaco;Nicholas S. Foulkes;Denis Masquilier

  • Developmental switch of CREM function during spermatogenesis: from antagonist to activator

    Nicholas S. Foulkes;Britt Mellström;Enrico Benusiglio;Paolo Sassone-Corsi

  • Light acts directly on organs and cells in culture to set the vertebrate circadian clock.

    David Whitmore;Nicholas S. Foulkes;Paolo Sassone-Corsi

  • Adrenergic signals direct rhythmic expression of transcriptional repressor CREM in the pineal gland

    Jërg H. Stehle;Nicholas S. Foulkes;Carlos A. Molina;Valérie Simonneaux

  • Zebrafish Clock rhythmic expression reveals independent peripheral circadian oscillators

    David Whitmore;Nicholas S. Foulkes;Uwe Strähle;Paolo Sassone-Corsi

  • More is better : activators and repressors from the same gene

    Nicholas S. Foulkes;Paolo Sassone-Corsi

  • Pituitary hormone FSH directs the CREM functional switch during spermatogenesis

    Nicholas S. Foulkes;Florence Schlotter;Paul Pévet;Paolo Sassone-Corsi

  • It’s time to swim! Zebrafish and the circadian clock

    Gad Vatine;Daniela Vallone;Yoav Gothilf;Nicholas S. Foulkes

  • Diverse point mutations in the human glucose-6-phosphate dehydrogenase gene cause enzyme deficiency and mild or severe hemolytic anemia

    T J Vulliamy;M D'Urso;G Battistuzzi;M Estrada

  • Cell cycle regulation of cyclin A gene expression by the cyclic AMP-responsive transcription factors CREB and CREM.

    C. Desdouets;G. Matesic;Carlos Molina;N. S. Foulkes

  • The functional versatility of CREM is determined by its modular structure.

    B M Laoide;N S Foulkes;F Schlotter;P Sassone-Corsi

  • Rhythmic transcription: The molecular basis of circadian melatonin synthesis

    Nicholas S. Foulkes;David Whitmore;Paolo Sassone-Corsi

  • A blind circadian clock in cavefish reveals that opsins mediate peripheral clock photoreception.

    Nicola Cavallari;Elena Frigato;Daniela Vallone;Nadine Fröhlich

  • Rhythmic Transcription: The Molecular Basis of Circadian Melatonin Synthesis

    Nicholas S. Foulkes;Jimo Borjigin;Solomon H. Snyder;Paolo Sassone-Corsi

  • Signal transduction and gene control: the cAMP pathway.

    Borrelli E;Montmayeur Jp;Foulkes Ns;Sassone-Corsi P

  • Light Regulates the Cell Cycle in Zebrafish

    Marcus P.S. Dekens;Cristina Santoriello;Daniela Vallone;Gabriele Grassi

  • A potent inhibitor of Taq polymerase copurifies with human genomic DNA

    R. de Franchis;N. C. P. Cross;N. S. Foulkes;T. M. Cox

  • Temperature regulates transcription in the zebrafish circadian clock.

    Kajori Lahiri;Daniela Vallone;Srinivas Babu Gondi;Cristina Santoriello

Frequent Co-Authors

Paolo Sassone-Corsi
Paolo Sassone-Corsi University of California, Irvine
Enzo Lalli
Enzo Lalli Centre national de la recherche scientifique, CNRS
Carlos A. Molina
Carlos A. Molina Montclair State University
Paul Pévet
Paul Pévet University of Strasbourg
Nicolas Cermakian
Nicolas Cermakian McGill University
Jose R. Naranjo
Jose R. Naranjo Spanish National Research Council
David C. Klein
David C. Klein National Institutes of Health
Lucio Luzzatto
Lucio Luzzatto University of Florence
Tom Vulliamy
Tom Vulliamy Queen Mary University of London

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