World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
96
Citations
33968
World Ranking
9662
National Ranking
4974

David C. Klein publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where David C. Klein sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 378 publications — 34th percentile

34% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

David C. Klein D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where David C. Klein sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 96 D-Index — 53rd percentile

53% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Overview

David C. Klein is a researcher affiliated with the National Institutes of Health in the United States. Their work primarily focuses on biochemical and medical topics, with significant contributions in molecular biology, neurology, physiology, biomedical engineering, and pathology and forensic medicine.

The main fields of study covered by their publications include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader fields, the subfields of molecular biology, neurology, physiology, biomedical engineering, and pathology and forensic medicine are prominently featured in their research output.

David C. Klein's research centers on several main topics, including:

  • Single-cell and spatial transcriptomics
  • Neuroinflammation and neurodegeneration mechanisms
  • Retinal development and disorders
  • Spinal cord injury research
  • Scoliosis diagnosis and treatment
  • Growth hormone and insulin-like growth factors
  • Adipose tissue and metabolism

Their recent publications reflect a focus on molecular and cellular processes related to the pineal gland and retina, as well as methodological approaches. Notable papers include:

  • "Resource: A multi-species multi-timepoint transcriptome database and webpage for the pineal gland and retina," 2020, Journal of Pineal Research
  • "Surgical Techniques and Nuances for Superior Cervical Ganglionectomy and Decentralization in Rats," 2022, Methods in Molecular Biology
  • "Two-Dimensional Thin Layer Chromatography of Melatonin and Related Compounds," 2022, Methods in Molecular Biology
  • "The Pineal Transcriptome Webpage," 2022, Methods in Molecular Biology
  • "Preparation of Single Pineal Cells," 2022, Methods in Molecular Biology

The frequent publication venues for Klein's work are:

  • Methods in Molecular Biology
  • Journal of Pineal Research
  • Endocrinología Diabetes y Nutrición
  • The Journal of Law Medicine & Ethics

Co-authorship collaborations are an element of their research activity, with frequent collaborators including:

  • Steven L. Coon
  • Eric Terry Wang Wei-Chiao Chang
  • Cong Fu
  • Shahar Alon
  • Marjan Bozinoski

Best Publications

  • Suprachiasmatic nucleus : the mind's clock

    D. C. Klein;Robert Y. Moore;Steven M. Reppert

  • Prostaglandins: Stimulation of Bone Resorption in Tissue Culture

    David C. Klein;Lawrence G. Raisz

  • Indole Metabolism in the Pineal Gland: A Circadian Rhythm in N-Acetyltransferase

    David C. Klein;Joan L. Weller

  • Visual pathways and the central neural control of a circadian rhythm in pineal serotonin N-acetyltransferase activity

    Robert Y. Moore;Robert Y. Moore;David C. Klein;David C. Klein

  • Pineal N-acetyltransferase and hydroxyindole-O-methyltransferase: control by the retinohypothalamic tract and the suprachiasmatic nucleus.

    David C. Klein;David C. Klein;Robert Y. Moore;Robert Y. Moore

  • The melatonin rhythm-generating enzyme: molecular regulation of serotonin N-acetyltransferase in the pineal gland.

    Klein Dc;Coon Sl;Roseboom Ph;Weller Jl

  • GCN5-RELATED N-ACETYLTRANSFERASES: A Structural Overview

    Fred Dyda;David C. Klein;Alison Burgess Hickman

  • Rapid Light-Induced Decrease in Pineal Serotonin N-Acetyltransferase Activity

    David C. Klein;Joan L. Weller

  • Activation of protein kinase C potentiates isoprenaline-induced cyclic AMP accumulation in rat pinealocytes

    David Sugden;Jiri Vanecek;David C. Klein;Thomas P. Thomas

  • Melatonin Production: Proteasomal Proteolysis in Serotonin N-acetyltransferase Regulation

    Jonathan A. Gastel;Patrick H. Roseboom;Peter A. Rinaldi;Joan L. Weller

  • Circadian clocks, clock networks, arylalkylamine N-acetyltransferase, and melatonin in the retina

    P. Michael Iuvone;Gianluca Tosini;Nikita Pozdeyev;Rashidul Haque

  • Pineal Serotonin N-Acetyltransferase: Expression Cloning and Molecular Analysis

    Steven L. Coon;Patrick H. Roseboom;Ruben Baler;Joan L. Weller

  • Natural melatonin `knockdown' in C57BL/6J mice: rare mechanism truncates serotonin N-acetyltransferase

    Patrick H Roseboom;M.A.Aryan Namboodiri;Drazen B Zimonjic;Nicholas C Popescu

  • Melatonin synthesis: analysis of the more than 150-fold nocturnal increase in serotonin N-acetyltransferase messenger ribonucleic acid in the rat pineal gland.

    Patrick H. Roseboom;Steven L. Coon;Ruben Baler;Susan K. McCUNE

  • Melatonin metabolism: neural regulation of pineal serotonin: acetyl coenzyme A N-acetyltransferase activity.

    David C. Klein;Joan L. Weller;Robert Y. Moore

  • Control of melatonin synthesis in the mammalian pineal gland: the critical role of serotonin acetylation.

    Surajit Ganguly;Steven L. Coon;David C. Klein

  • Postsynaptic alpha-adrenergic receptors potentiate the beta-adrenergic stimulation of pineal serotonin N-acetyltransferase

    David C. Klein;David Sugden;Joan L. Weller

  • Lesions of the paraventricular nucleus area of the hypothalamus disrupt the suprachiasmatic→ spinal cord circuit in the melatonin rhythm generating system

    D.C. Klein;R. Smoot;J.L. Weller;S. Higa

  • Melatonin Synthesis: Adenosine 3',5'-Monophosphate and Norepinephrine Stimulate N-Acetyltransferase

    David C. Klein;Gerald R. Berg;Joan Weller

  • Atypical synergistic α1- and β-adrenergic regulation of adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate in rat pinealocytes

    Jiri Vanecek;David Sugden;Joan Weller;David C. Klein

Frequent Co-Authors

Morten Møller
Morten Møller University of Copenhagen
Fred Dyda
Fred Dyda National Institutes of Health
Rashidul Haque
Rashidul Haque International Centre for Diarrhoeal Disease Research
P. Michael Iuvone
P. Michael Iuvone Emory University
Steven M. Reppert
Steven M. Reppert University of Massachusetts Chan Medical School
Kenneth L. Kirk
Kenneth L. Kirk National Institutes of Health
Valentín Ceña
Valentín Ceña University of Castilla-La Mancha
Igal Gery
Igal Gery National Institutes of Health
Gilles Boeuf
Gilles Boeuf Centre national de la recherche scientifique, CNRS
Philip A. Cole
Philip A. Cole Brigham and Women's Hospital

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