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Biology and Biochemistry

D-Index
54
Citations
10951
World Ranking
15600
National Ranking
631

Overview

Enzo Lalli is affiliated with the Centre national de la recherche scientifique (CNRS) in France. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine, with a focus on Molecular Biology, Genetics, Endocrinology, Diabetes and Metabolism, Cancer Research, and Oncology.

The main research topics addressed by Lalli include:

  • Adrenal and Paraganglionic Tumors
  • Cancer, Hypoxia, and Metabolism
  • Hormonal Regulation and Hypertension
  • Cancer-related Molecular Pathways
  • Ubiquitin and proteasome pathways
  • Glioma Diagnosis and Treatment
  • Phosphodiesterase function and regulation

Lalli has collaborated frequently with a group of co-authors who have contributed extensively to their scientific output. These include Bonald C. Figueiredo, Carmen Ruggiero, Mabrouka Doghman, Gerard P. Zambetti, and Emília M. Pinto.

Their recent publications cover a variety of topics related to cancer biology, cellular mechanisms, and genetic predisposition. Notable recent papers include:

  • "Targeting the cytoskeleton against metastatic dissemination," 2021, published in Cancer and Metastasis Reviews
  • "XAF1 as a modifier of p53 function and cancer susceptibility," 2020, published in Science Advances
  • "Germline Variants in Phosphodiesterase Genes and Genetic Predisposition to Pediatric Adrenocortical Tumors," 2020, published in Cancers
  • "The Common Germline TP53-R337H Mutation Is Hypomorphic and Confers Incomplete Penetrance and Late Tumor Onset in a Mouse Model," 2021, published in Cancer Research
  • "Steroidogenic Factor 1, a Goldilocks Transcription Factor from Adrenocortical Organogenesis to Malignancy," 2023, published in International Journal of Molecular Sciences

Lalli frequently publishes in venues such as Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, European Journal of Endocrinology, Cancers, Endocrine Abstracts, and bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita

    Elena Zanaria;Françoise Muscatelli;Barbara Bardoni;Tim M. Strom

  • Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor.

    Carlos A. Molina;Nicholas S. Foulkes;Enzo Lalli;Paolo Sassone-Corsi

  • Signal transduction and gene regulation: the nuclear response to cAMP.

    E Lalli;P Sassone-Corsi

  • DNA binding and transcriptional repression by DAX-1 blocks steroidogenesis

    Emmanuel Zazopoulos;Enzo Lalli;Douglas M. Stocco;Paolo Sassone-Corsi

  • Steroidogenic factor 1 and Dax-1 colocalize in multiple cell lineages: potential links in endocrine development.

    Yoi Ikeda;Amanda Swain;Thomas J. Weber;Kathryn E. Hentges

  • Regulation of Steroidogenesis and the Steroidogenic Acute Regulatory Protein by a Member of the cAMP Response-Element Binding Protein Family

    Pulak R. Manna;Matthew T. Dyson;Darrell W. Eubank;Barbara J. Clark

  • Regulation of Insulin-like Growth Factor-Mammalian Target of Rapamycin Signaling by MicroRNA in Childhood Adrenocortical Tumors

    Mabrouka Doghman;Abeer El Wakil;Bruno Cardinaud;Emilie Thomas

  • Increased Steroidogenic Factor-1 dosage triggers adrenocortical cell proliferation and cancer.

    Mabrouka Doghman;Tatiana Karpova;Giovanna Assis Rodrigues;Malika Arhatte

  • Invalidation of TASK1 potassium channels disrupts adrenal gland zonation and mineralocorticoid homeostasis.

    Dirk Heitzmann;Renaud Derand;Stefan Jungbauer;Sascha Bandulik

  • DAX-1 blocks steroid production at multiple levels.

    Enzo Lalli;Michael H. Melner;Douglas M. Stocco;Paolo Sassone-Corsi

  • A Transcriptional Silencing Domain in DAX-1 Whose Mutation Causes Adrenal Hypoplasia Congenita

    Enzo Lalli;Barbara Bardoni;Emmanuel Zazopoulos;Jean-Marie Wurtz

  • Impact of Neonatal Screening and Surveillance for the TP53 R337H Mutation on Early Detection of Childhood Adrenocortical Tumors

    Gislaine Custódio;Guilherme A. Parise;Nilton Kiesel Filho;Heloisa Komechen

  • DAX-1, an Unusual Orphan Receptor at the Crossroads of Steroidogenic Function and Sexual Differentiation

    Enzo Lalli;Paolo Sassone-Corsi

  • Gene expression profiling of childhood adrenocortical tumors

    Alina Nico West;Geoffrey A Neale;Stanley Pounds;Bonald C Figueredo

  • Adrenal Cortex Remodeling and Functional Zona Glomerulosa Hyperplasia in Primary Aldosteronism

    Sheerazed Boulkroun;Benoit Samson-Couterie;José-Felipe Golib Dzib;Hervé Lefebvre

  • The Wnt/beta-catenin pathway in adrenocortical development and cancer.

    Abeer El Wakil;Enzo Lalli;Enzo Lalli

  • Transcriptional regulation of the mouse steroidogenic acute regulatory protein gene by the cAMP response-element binding protein and steroidogenic factor 1

    PR Manna;DW Eubank;E Lalli;P Sassone-Corsi

  • Hormonal and Developmental Regulation of DAX-1 Expression in Sertoli Cells

    Katherine T. Tamai;Lucia Monaco;Tero-Pekka Alastalo;Enzo Lalli

  • Amplification of the steroidogenic factor 1 gene in childhood adrenocortical tumors.

    Bonald C. Figueiredo;Luciane R. Cavalli;Mara Albonei D. Pianovski;Enzo Lalli

  • A direct role of SRY and SOX proteins in pre-mRNA splicing

    Kenji Ohe;Enzo Lalli;Paolo Sassone-Corsi

Frequent Co-Authors

Paolo Sassone-Corsi
Paolo Sassone-Corsi University of California, Irvine
Gerard P. Zambetti
Gerard P. Zambetti St. Jude Children's Research Hospital
Raul C. Ribeiro
Raul C. Ribeiro St. Jude Children's Research Hospital
Barbara Bardoni
Barbara Bardoni Université Côte d'Azur
Jacques Barhanin
Jacques Barhanin Centre national de la recherche scientifique, CNRS
Nicholas S. Foulkes
Nicholas S. Foulkes Karlsruhe Institute of Technology
Felix Beuschlein
Felix Beuschlein University of Zurich
Jérôme Bertherat
Jérôme Bertherat Université Paris Cité
Douglas M. Stocco
Douglas M. Stocco Texas Tech University Health Sciences Center
Martin Fassnacht
Martin Fassnacht University of Würzburg

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