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Immunology

D-Index
91
Citations
30383
World Ranking
1036
National Ranking
561

Research.com Recognitions

  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Leo Lefrançois was affiliated with the University of Connecticut Health Center in the United States. Their research primarily focused on immunology and microbiology, with additional contributions to biochemistry, genetics, and molecular biology.

The main topics of Lefrançois's work included:

  • Immunotherapy and Immune Responses
  • Listeria monocytogenes in Food Safety
  • T-cell and B-cell Immunology

Lefrançois contributed to the subfields of immunology and biotechnology, reflecting a specialized focus within their broader scientific interests.

Their recent publications included:

  • Mucosal CD8 T Cell Responses Are Shaped by Batf3-DC After Foodborne Listeria monocytogenes Infection (2020), published in Frontiers in Immunology
  • Diverse dendritic cell subsets promote infection and induction of CD8 T cell responses after foodborne Listeria monocytogenes infection (2020), published in The Journal of Immunology

Throughout their career, Lefrançois frequently collaborated with the following co-authors:

  • Jessica Nancy Imperato
  • Pablo A. Romagnoli
  • Zhijuan Qiu
  • Pedro Pérez
  • Quynh-Mai Pham

Lefrançois's research was published in notable venues such as:

  • Frontiers in Immunology
  • The Journal of Immunology

In recognition of their contributions to science, Leo Lefrançois was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2009.

Best Publications

  • Preferential Localization of Effector Memory Cells in Nonlymphoid Tissue

    David Masopust;Vaiva Vezys;Amanda L. Marzo;Leo Lefrançois

  • Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo.

    Kimberly S. Schluns;William C Kieper;Stephen C. Jameson;Leo Lefrançois

  • Cytokine control of memory T-cell development and survival

    Kimberly S. Schluns;Leo Lefrançois

  • Expression of the γ-δ T-cell receptor on intestinal CD8+ intraepithelial lymphocytes

    Thomas Goodman;Leo Lefrançois

  • Cutting Edge: Requirement for IL-15 in the Generation of Primary and Memory Antigen-Specific CD8 T Cells

    Kimberly S. Schluns;Kristina Williams;Averil Ma;Xin X. Zheng

  • Cutting Edge: Tissue-Retentive Lung Memory CD4 T Cells Mediate Optimal Protection to Respiratory Virus Infection

    John R. Teijaro;Damian Turner;Quynh Pham;E. John Wherry

  • Initial T cell frequency dictates memory CD8+ T cell lineage commitment.

    Amanda L Marzo;Kimberly D Klonowski;Agnes Le Bon;Persephone Borrow

  • Combined IL-15/IL-15Rα Immunotherapy Maximizes IL-15 Activity In Vivo

    Thomas A. Stoklasek;Kimberly S. Schluns;Leo Lefrançois

  • Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection.

    Joshua J. Obar;Kamal M. Khanna;Leo Lefrançois

  • Heat Shock Protein gp96 Is a Master Chaperone for Toll-like Receptors and Is Important in the Innate Function of Macrophages

    Yi Yang;Bei Liu;Jie Dai;Pramod K. Srivastava

  • Mucosal T lymphocyte numbers are selectively reduced in integrin alpha E (CD103)-deficient mice

    Michael P. Schön;Anu Arya;Elizabeth A. Murphy;Cassandra M. Adams

  • Organ-specific regulation of the CD8 T cell response to Listeria monocytogenes infection.

    Constance Pope;Sung-Kwon Kim;Amanda Marzo;Kristina Williams

  • Intraepithelial lymphocytes. Anatomical site, not T cell receptor form, dictates phenotype and function.

    T Goodman;L Lefrancois

  • Dynamics of Blood-Borne CD8 Memory T Cell Migration In Vivo

    Kimberly D Klonowski;Kristina J Williams;Amanda L Marzo;David A Blair

  • Cutting Edge: Intravascular Staining Redefines Lung CD8 T Cell Responses

    Kristin G. Anderson;Heungsup Sung;Cara N. Skon;Leo Lefrancois

  • Dendritic cells maximize the memory CD8 T cell response to infection.

    David J. Zammit;Linda S. Cauley;Quynh-Mai Pham;Leo Lefrançois

  • Activated primary and memory CD8 T cells migrate to nonlymphoid tissues regardless of site of activation or tissue of origin.

    David Masopust;Vaiva Vezys;Edward J. Usherwood;Linda S. Cauley

  • Oral Infection Drives a Distinct Population of Intestinal Resident Memory CD8+ T Cells with Enhanced Protective Function

    Brian S. Sheridan;Quynh-Mai Pham;Young-Tae Lee;Linda S. Cauley

  • In vivo modulation of cytolytic activity and Thy-1 expression in TCR-gamma delta+ intraepithelial lymphocytes.

    Leo Lefrancois;Thomas Goodman

  • Phenotypic complexity of intraepithelial lymphocytes of the small intestine.

    L Lefrancois

  • Mucosal T Lymphocyte Numbers Are Selectively Reduced in Integrin αE (CD103)-Deficient Mice

    Unknown

Frequent Co-Authors

David Masopust
David Masopust University of Minnesota
Anthony T. Vella
Anthony T. Vella University of Connecticut Health Center
Stephen C. Jameson
Stephen C. Jameson University of Minnesota
Donna L. Farber
Donna L. Farber Columbia University
Hao Shen
Hao Shen University of Pennsylvania
Hideo Yagita
Hideo Yagita Juntendo University
Stephen J. McSorley
Stephen J. McSorley University of California, Davis
David F. Tough
David F. Tough GlaxoSmithKline (United Kingdom)
Jeffrey A. Bluestone
Jeffrey A. Bluestone University of California, San Francisco

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