D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 75 Citations 20,536 130 World Ranking 841 National Ranking 468

Research.com Recognitions

Awards & Achievements

2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Immune system
  • T cell
  • Antigen

Leo Lefrançois mainly focuses on Immunology, Cytotoxic T cell, Cell biology, T cell and CD8. His work on Immune system and Antigen as part of general Immunology study is frequently linked to Population, therefore connecting diverse disciplines of science. His Cytotoxic T cell study integrates concerns from other disciplines, such as Virus, Cytokine and Spleen.

His research in Cell biology intersects with topics in CD28, Tumor necrosis factor alpha and Antigen-presenting cell. He combines subjects such as T lymphocyte, Lamina propria, Molecular biology, Lymphatic system and Intraepithelial lymphocyte with his study of CD8. In IL-2 receptor, he works on issues like Interleukin 21, which are connected to Jurkat cells.

His most cited work include:

  • Preferential Localization of Effector Memory Cells in Nonlymphoid Tissue (1637 citations)
  • Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo. (1416 citations)
  • Cytokine control of memory T-cell development and survival (772 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Immunology, Cytotoxic T cell, Cell biology, T cell and CD8. His Immunology research includes themes of Molecular biology and Intestinal mucosa. Much of his study explores Cytotoxic T cell relationship to Antigen.

His work carried out in the field of Cell biology brings together such families of science as Adoptive cell transfer, Memory T cell, Cytokine and Interleukin 15. His T cell research includes elements of Haematopoiesis and Immune tolerance. His IL-2 receptor study combines topics from a wide range of disciplines, such as Natural killer T cell and Priming.

He most often published in these fields:

  • Immunology (61.88%)
  • Cytotoxic T cell (56.93%)
  • Cell biology (32.67%)

What were the highlights of his more recent work (between 2012-2020)?

  • Immunology (61.88%)
  • Cytotoxic T cell (56.93%)
  • Cell biology (32.67%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Immunology, Cytotoxic T cell, Cell biology, T cell and Intestinal mucosa. In general Immunology, his work in Effector, Immune system, Priming and Lymphocyte is often linked to Population linking many areas of study. His study in Interleukin 21 and IL-2 receptor is carried out as part of his studies in Cytotoxic T cell.

As a part of the same scientific study, Leo Lefrançois usually deals with the Interleukin 21, concentrating on Antigen-presenting cell and frequently concerns with CD40 and Intraepithelial lymphocyte. His T cell research is multidisciplinary, incorporating perspectives in Progenitor cell and Haematopoiesis. Leo Lefrançois combines subjects such as Intestinal epithelium, Mesenteric lymph nodes, Antigen, Immunity and Microbiology with his study of Intestinal mucosa.

Between 2012 and 2020, his most popular works were:

  • Oral Infection Drives a Distinct Population of Intestinal Resident Memory CD8+ T Cells with Enhanced Protective Function (179 citations)
  • γδ T Cells Exhibit Multifunctional and Protective Memory in Intestinal Tissues (131 citations)
  • Environmental Cues Dictate the Fate of Individual CD8+ T Cells Responding to Infection (97 citations)

In his most recent research, the most cited papers focused on:

  • Immune system
  • Antibody
  • Antigen

His primary scientific interests are in Immunology, Cell biology, Intestinal mucosa, Cytotoxic T cell and Immune system. His work on T cell, Immunity, Adoptive cell transfer and Effector is typically connected to Population as part of general Immunology study, connecting several disciplines of science. His research in T cell tackles topics such as Antigen which are related to areas like Interferon gamma.

The Effector study combines topics in areas such as Immunologic memory, CD8 and Sensory cue. Leo Lefrançois has included themes like IL-2 receptor, Natural killer T cell, Interleukin 21, Granzyme B production and ZAP70 in his Cell biology study. His study in Cytotoxic T cell focuses on Antigen-presenting cell and Interleukin-7 receptor.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Preferential Localization of Effector Memory Cells in Nonlymphoid Tissue

David Masopust;Vaiva Vezys;Amanda L. Marzo;Leo Lefrançois.
Science (2001)

2646 Citations

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo.

Kimberly S. Schluns;William C Kieper;Stephen C. Jameson;Leo Lefrançois.
Nature Immunology (2000)

1608 Citations

Cytokine control of memory T-cell development and survival

Kimberly S. Schluns;Leo Lefrançois.
Nature Reviews Immunology (2003)

1182 Citations

Expression of the γ-δ T-cell receptor on intestinal CD8+ intraepithelial lymphocytes

Thomas Goodman;Leo Lefrançois.
Nature (1988)

873 Citations

Cutting Edge: Requirement for IL-15 in the Generation of Primary and Memory Antigen-Specific CD8 T Cells

Kimberly S. Schluns;Kristina Williams;Averil Ma;Xin X. Zheng.
Journal of Immunology (2002)

693 Citations

Organ-specific regulation of the CD8 T cell response to Listeria monocytogenes infection.

Constance Pope;Sung-Kwon Kim;Amanda Marzo;Kristina Williams.
Journal of Immunology (2001)

545 Citations

Initial T cell frequency dictates memory CD8+ T cell lineage commitment

Amanda L Marzo;Kimberly D Klonowski;Agnes Le Bon;Persephone Borrow.
Nature Immunology (2005)

511 Citations

Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection.

Joshua J. Obar;Kamal M. Khanna;Leo Lefrançois.
Immunity (2008)

458 Citations

Heat Shock Protein gp96 Is a Master Chaperone for Toll-like Receptors and Is Important in the Innate Function of Macrophages

Yi Yang;Bei Liu;Jie Dai;Pramod K. Srivastava.
Immunity (2007)

455 Citations

Combined IL-15/IL-15Rα Immunotherapy Maximizes IL-15 Activity In Vivo

Thomas A. Stoklasek;Kimberly S. Schluns;Leo Lefrançois.
Journal of Immunology (2006)

449 Citations

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