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Nicholas T. Ktistakis

Nicholas T. Ktistakis

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
45278
World Ranking
11641
National Ranking
894

Overview

Nicholas T. Ktistakis is affiliated with the Babraham Institute in the United Kingdom. Their research primarily spans the fields of medicine and biochemistry, genetics, and molecular biology, with significant contributions in areas such as epidemiology, molecular biology, cell biology, neurology, and physiology.

The core topics in Ktistakis's work include autophagy in disease and therapy, endoplasmic reticulum stress and disease, ubiquitin and proteasome pathways, Toxoplasma gondii research studies, cannabis and cannabinoid research, neuroinflammation and neurodegeneration mechanisms, and epigenetics and DNA methylation.

Ktistakis has published in several reputable venues. Frequent publication journals are:

  • Autophagy
  • The EMBO Journal
  • Nature
  • Frontiers in Cell and Developmental Biology
  • Biochemical Society Transactions

The scientist has co-authored extensively with the following colleagues:

  • Maria Manifava (13 co-publications)
  • Daniel J. Klionsky (3 co-publications)
  • Eeva-Liisa Eskelinen (3 co-publications)
  • Christian Münz (3 co-publications)
  • Junichi Sadoshima (3 co-publications)

Recent papers by Ktistakis include:

  • "Autophagy in major human diseases," 2021, published in The EMBO Journal
  • "Mitochondrial Oxidative Damage Underlies Regulatory T Cell Defects in Autoimmunity," 2020, Cell Metabolism
  • "International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis," 2024, Autophagy
  • "CDK1, the Other 'Master Regulator' of Autophagy," 2020, Trends in Cell Biology
  • "Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk," 2020, Nature Communications

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

    Elizabeth L. Axe;Simon A. Walker;Maria Manifava;Priya Chandra

  • Molecular definitions of autophagy and related processes

    Lorenzo Galluzzi;Lorenzo Galluzzi;Eric H. Baehrecke;Andrea Ballabio;Patricia Boya

  • Autophagy in major human diseases

    Daniel J. Klionsky;Giulia Petroni;Ravi K. Amaravadi;Eric H. Baehrecke

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Phospholipid metabolism regulated by a transcription factor sensing phosphatidic acid.

    C. J. R. Loewen;M. L. Gaspar;S. A. Jesch;C. Delon

  • Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L

    Kohichi Matsunaga;Eiji Morita;Tatsuya Saitoh;Shizuo Akira

  • Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesicles.

    N T Ktistakis;H A Brown;M G Waters;P C Sternweis

  • Phosphatidic acid- and phosphatidylserine-binding proteins

    Catherine L Stace;Nicholas T Ktistakis

  • Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices

    S. Krugmann;K.E. Anderson;S.H. Ridley;N. Risso

  • Digesting the Expanding Mechanisms of Autophagy

    Nicholas T. Ktistakis;Sharon A. Tooze

  • Autophagy initiation by ULK complex assembly on ER tubulovesicular regions marked by ATG9 vesicles

    Eleftherios Karanasios;Simon A. Walker;Hanneke Okkenhaug;Maria Manifava

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Dynamic association of the ULK1 complex with omegasomes during autophagy induction.

    Eleftherios Karanasios;Eloise Stapleton;Maria Manifava;Takeshi Kaizuka;Takeshi Kaizuka

  • Regulation of autophagy by phosphatidylinositol 3-phosphate

    Chloe Burman;Nicholas T. Ktistakis

  • Sphingosine kinase 1 is an intracellular effector of phosphatidic acid

    Christine Delon;Maria Manifava;Eleanor Wood;Dawn Thompson

  • Coronavirus nsp6 proteins generate autophagosomes from the endoplasmic reticulum via an omegasome intermediate

    Eleanor M. Cottam;Helena J. Maier;Maria Manifava;Laura C. Vaux

  • Autophagosome formation in mammalian cells

    Chloe Burman;Nicholas T. Ktistakis

Frequent Co-Authors

Michael G. Roth
Michael G. Roth The University of Texas Southwestern Medical Center
Francesco Cecconi
Francesco Cecconi Catholic University of the Sacred Heart
Noboru Mizushima
Noboru Mizushima University of Tokyo
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Sharon A. Tooze
Sharon A. Tooze The Francis Crick Institute
Tamotsu Yoshimori
Tamotsu Yoshimori Osaka University
Sergio Lavandero
Sergio Lavandero University of Chile
Vojo Deretic
Vojo Deretic University of New Mexico
Gábor Juhász
Gábor Juhász Eötvös Loránd University
Fulvio Reggiori
Fulvio Reggiori University of Groningen

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