World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
16996
World Ranking
10083
National Ranking
4411

Overview

Michael G. Roth is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research primarily focuses on the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with additional emphasis on subfields such as Cell Biology, Oncology, Molecular Biology, Surgery, and Epidemiology.

The scientist's work covers several key topics, including:

  • Microtubule and mitosis dynamics
  • Cancer-related Molecular Pathways
  • Cardiac Arrest and Resuscitation
  • Hemodynamic Monitoring and Therapy
  • Neuroendocrine Tumor Research Advances
  • Cancer Research and Treatments
  • Meat and Animal Product Quality

Roth's publications have appeared in a variety of academic venues, with several contributions to:

  • Cancer Research
  • Critical Care Medicine
  • Kansas Agricultural Experiment Station Research Reports
  • Frontiers in Endocrinology
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature

Notable recent papers include:

  • Loss of Aurora Kinase Signaling Allows Lung Cancer Cells to Adopt Endoreplication and Form Polyploid Giant Cancer Cells That Resist Antimitotic Drugs, 2020, Cancer Research
  • Abstract PO-128: Lack of Aurora kinase signaling leads cancer cells to adopt an endocycle and form polyploid multinucleated giant cells that resist antimitotic drugs, 2020, Cancer Research
  • Exploring the Potential Effect of Phospholipase A2 Antibody to Extend Beef Shelf-Life in a Beef Liposome Model System, 2022, Kansas Agricultural Experiment Station Research Reports
  • Small molecule glucagon release inhibitors with activity in human islets, 2023, Frontiers in Endocrinology
  • Abstract 4396: A bioinformatics approach for cancer immunotherapeutic target identification by evaluating surfaceome gene and protein expression (CITIESGAPE) in tumor and pan-normal tissues, 2020, Cancer Research

Frequent collaborators include:

  • Vural Tagal
  • Brendan Sweeney
  • Justin Kim
  • Ariana Adnani
  • Maria Wu

This profile shows a multidisciplinary approach, with contributions to both basic and applied biomedical research, including cancer biology, immunotherapy target identification, and quality control of meat products. The range of publications underscores involvement in experimental, computational, and translational research aspects.

Best Publications

  • Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

    Baozhi Chen;Michael E. Dodge;Wei Tang;Jianming Lu

  • Role of lipid modifications in targeting proteins to detergent-resistant membrane rafts. Many raft proteins are acylated, while few are prenylated.

    Karin A. Melkonian;Anne G. Ostermeyer;James Z. Chen;Michael G. Roth

  • Interaction of influenza virus haemagglutinin with sphingolipid–cholesterol membrane domains via its transmembrane domain

    Peter Scheiffele;Michael G. Roth;Kai Simons

  • Phosphatidylinositol 4,5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3

    A.L. Rozelle;L.M. Machesky;M. Yamamoto;M.H.E. Driessens

  • Phosphatidylinositol 4 Phosphate Regulates Targeting of Clathrin Adaptor AP-1 Complexes to the Golgi

    Ying Jie Wang;Jing Wang;Hui Qiao Sun;Manuel Martinez

  • Targeting QseC Signaling and Virulence for Antibiotic Development

    David A. Rasko;Cristiano G. Moreira;De Run Li;Nicola C. Reading

  • Synthetic lethal screen identification of chemosensitizer loci in cancer cells

    Angelique W. Whitehurst;Brian O. Bodemann;Jessica Cardenas;Deborah Ferguson

  • Image-based genome-wide siRNA screen identifies selective autophagy factors

    Anthony Orvedahl;Rhea Sumpter;Guanghua Xiao;Aylwin Ng;Aylwin Ng

  • Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesicles.

    N T Ktistakis;H A Brown;M G Waters;P C Sternweis

  • Phosphoinositides in constitutive membrane traffic

    Michael G. Roth

  • A single amino acid change in the cytoplasmic domain alters the polarized delivery of influenza virus hemagglutinin.

    Colleen B. Brewer;Michael G. Roth

  • The Liver X Receptor Ligand T0901317 Decreases Amyloid β Production in Vitro and in a Mouse Model of Alzheimer's Disease

    Radosveta P. Koldamova;Iliya M. Lefterov;Matthias Staufenbiel;Darren Wolfe

  • A Single Amino Acid Change in the Cytoplasmic Domain Allows the Influenza Virus Hemagglutinin to Be Endocytosed through Coated Pits

    Janette Lazarovits;Michael G Roth

  • Different biosynthetic transport routes to the plasma membrane in BHK and CHO cells.

    Tamotsu Yoshimori;Patrick Keller;Michael G. Roth;Kai Simons

  • High-throughput Screening for Potent and Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase

    Jeffrey Baldwin;Carolyn H. Michnoff;Nicholas A. Malmquist;John White

  • Differential extractability of influenza virus hemagglutinin during intracellular transport in polarized epithelial cells and nonpolar fibroblasts.

    J E Skibbens;M G Roth;K S Matlin

  • Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin A

    N T Ktistakis;H A Brown;P C Sternweis;M G Roth

  • Mutations in the Middle of the Transmembrane Domain Reverse the Polarity of Transport of the Influenza Virus Hemagglutinin in MDCK Epithelial Cells

    Sasa Lin;Hussein Y. Naim;A. Chapin Rodriguez;Michael G. Roth

  • Characteristics of the tyrosine recognition signal for internalization of transmembrane surface glycoproteins

    Nicholas T. Ktistakis;D'Nette Thomas;Michael G. Roth

  • ARNO and ARF6 Regulate Axonal Elongation and Branching through Downstream Activation of Phosphatidylinositol 4-Phosphate 5-Kinase α

    Delia J. Hernández-Deviez;Michael G. Roth;James E. Casanova;Jean M. Wilson

Frequent Co-Authors

Michael A. White
Michael A. White Ideaya Biosciences (United States)
Nicholas T. Ktistakis
Nicholas T. Ktistakis Babraham Institute
John D. Minna
John D. Minna The University of Texas Southwestern Medical Center
Jef K. De Brabander
Jef K. De Brabander The University of Texas Southwestern Medical Center
Yoav I. Henis
Yoav I. Henis Tel Aviv University
Roger H Unger
Roger H Unger The University of Texas Southwestern Medical Center
Noelle S. Williams
Noelle S. Williams The University of Texas Southwestern Medical Center
Adi F. Gazdar
Adi F. Gazdar The University of Texas Southwestern Medical Center
Luc Girard
Luc Girard The University of Texas Southwestern Medical Center
Young Hee Lee
Young Hee Lee Sungkyunkwan University

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