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Immunology

D-Index
72
Citations
15256
World Ranking
2255
National Ranking
1090

Overview

Eric Pearlman is affiliated with the University of California, Irvine in the United States. Their research spans multiple fields, primarily in medicine and biochemistry, genetics, and molecular biology.

Their work covers various subfields including psychiatry and mental health, immunology, molecular biology, pathology and forensic medicine, and ophthalmology.

Major topics addressed in their research include:

  • Migraine and headache studies
  • Immune response and inflammation
  • Inflammasome and immune disorders
  • Trigeminal neuralgia and treatments
  • Bacterial biofilms and quorum sensing
  • Bacteriophages and microbial interactions
  • Psychosomatic disorders and their treatments

Eric Pearlman has contributed to publications in several scientific journals and platforms. Frequent venues for their work include:

  • Neurology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Headache The Journal of Head and Face Pain
  • The Journal of Headache and Pain

Their recent papers exemplify a focus on immunology and migraine-related studies:

  • "N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis," 2020, Nature Communications
  • "Diagnosis, consultation, treatment, and impact of migraine in the US: Results of the OVERCOME (US) study," 2022, Headache The Journal of Head and Face Pain
  • "The genome of opportunistic fungal pathogen Fusarium oxysporum carries a unique set of lineage-specific chromosomes," 2020, Communications Biology
  • "Medication overuse in a subgroup analysis of phase 3 placebo-controlled studies of galcanezumab in the prevention of episodic and chronic migraine," 2020, Cephalalgia
  • "Migraine-Related Stigma and Its Relationship to Disability, Interictal Burden, and Quality of Life," 2024, Neurology

Collaborative work is a component of Pearlman's research profile, with frequent coauthors including:

  • Michaela Marshall
  • Serena Abbondante
  • Richard B. Lipton
  • Robert A. Nicholson
  • Dawn C. Buse

Best Publications

  • Targeted Disruption of the Chemokine Eotaxin Partially Reduces Antigen-induced Tissue Eosinophilia

    Marc E. Rothenberg;James A. MacLean;Eric Pearlman;Andrew D. Luster

  • Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP.

    Mausita Karmakar;Michael A. Katsnelson;George R. Dubyak;Eric Pearlman

  • Activation of neutrophils by autocrine IL-17A-IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2.

    Patricia R Taylor;Sanhita Roy;Sixto M Leal;Yan Sun

  • EOTAXIN IS REQUIRED FOR THE BASELINE LEVEL OF TISSUE EOSINOPHILS

    Angela N. Matthews;Daniel S. Friend;Nives Zimmermann;Mindy N. Sarafi

  • Cutting edge: Membrane nanotubes in vivo: a feature of MHC class II+ cells in the mouse cornea.

    Holly R. Chinnery;Eric Pearlman;Paul G. McMenamin

  • Expression of hyaluronidase by tumor cells induces angiogenesis in vivo

    Dacai Liu;Eric Pearlman;Eugenia Diaconu;Kun Guo

  • Stem Cell Therapy Restores Transparency to Defective Murine Corneas

    Yiqin Du;Eric C. Carlson;Martha L. Funderburgh;David E. Birk

  • Neutrophil IL-1β Processing Induced by Pneumolysin Is Mediated by the NLRP3/ASC Inflammasome and Caspase-1 Activation and Is Dependent on K+ Efflux

    Mausita Karmakar;Michael Katsnelson;Hesham A. Malak;Neil G. Greene

  • Endogenous IL-12 is required for control of Th2 cytokine responses capable of exacerbating leishmaniasis in normally resistant mice.

    F. P. Heinzel;R. M. Rerko;Farah Ahmed;E. Pearlman

  • Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation.

    Angela C. Johnson;Fred P. Heinzel;Fred P. Heinzel;Eugenia Diaconu;Yan Sun

  • The rodA hydrophobin on Aspergillus fumigatus spores masks dectin-1- and dectin-2-dependent responses and enhances fungal survival in vivo

    Steven De Jesus Carrion;Sixto M. Leal;Mahmoud A. Ghannoum;Vishukumar Aimanianda

  • Distinct Roles for Dectin-1 and TLR4 in the Pathogenesis of Aspergillus fumigatus Keratitis

    Sixto M. Leal;Susan Cowden;Yen Cheng Hsia;Mahmoud A. Ghannoum

  • Photoreceptor proteins initiate microglial activation via Toll-like receptor 4 in retinal degeneration mediated by all-trans-retinal.

    Hideo Kohno;Yu Chen;Brian M. Kevany;Eric Pearlman

  • Zinc and Manganese Chelation by Neutrophil S100A8/A9 (Calprotectin) Limits Extracellular Aspergillus fumigatus Hyphal Growth and Corneal Infection

    Heather L. Clark;Heather L. Clark;Anupam Jhingran;Yan Sun;Chairut Vareechon

  • Wolbachia Lipoprotein Stimulates Innate and Adaptive Immunity through Toll-like Receptors 2 and 6 to Induce Disease Manifestations of Filariasis

    Joseph D. Turner;R. Stuart Langley;Kelly L. Johnston;Katrin Gentil

  • Modulation of murine cytokine responses to mycobacterial antigens by helminth-induced T helper 2 cell responses.

    E Pearlman;J W Kazura;F E Hazlett;W H Boom

  • Onchocerciasis: the Role of Wolbachia Bacterial Endosymbionts in Parasite Biology, Disease Pathogenesis, and Treatment

    Francesca Tamarozzi;Alice Halliday;Katrin Gentil;Achim Hoerauf

  • Cutting Edge: IL-1β Processing during Pseudomonas aeruginosa Infection Is Mediated by Neutrophil Serine Proteases and Is Independent of NLRC4 and Caspase-1

    Mausita Karmakar;Yan Sun;Amy G. Hise;Arne Rietsch

  • TLR4 and TLR5 on Corneal Macrophages Regulate Pseudomonas aeruginosa Keratitis by Signaling through MyD88-Dependent and -Independent Pathways

    Yan Sun;Mausita Karmakar;Sanhita Roy;Raniyah T. Ramadan

  • Fungal antioxidant pathways promote survival against neutrophils during infection

    Sixto M. Leal;Chairut Vareechon;Susan Cowden;Brian A. Cobb

  • Pathogenesis of Onchocercal Keratitis (River Blindness)

    Laurie R. Hall;Eric Pearlman

Frequent Co-Authors

James W. Kazura
James W. Kazura Case Western Reserve University
Thomas R. Unnasch
Thomas R. Unnasch University of South Florida
Mahmoud A. Ghannoum
Mahmoud A. Ghannoum Case Western Reserve University
Mark J. Taylor
Mark J. Taylor Liverpool School of Tropical Medicine
Jean-Paul Latgé
Jean-Paul Latgé University of Crete
Pranab K. Mukherjee
Pranab K. Mukherjee Louisiana State University
Achim Hoerauf
Achim Hoerauf University of Bonn
Winston W.-Y. Kao
Winston W.-Y. Kao University of Cincinnati
Scott G. Filler
Scott G. Filler University of California, Los Angeles
Tadao Maeda
Tadao Maeda Case Western Reserve University

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