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Biology and Biochemistry

D-Index
53
Citations
9369
World Ranking
16242
National Ranking
6726

Overview

Rajini Rao is affiliated with the Johns Hopkins University School of Medicine in the United States. Their research predominantly spans the fields of Biochemistry, Genetics and Molecular Biology, with additional work in Medicine. The subfields of study emphasized in their work include Molecular Biology, Physiology, Cell Biology, Genetics, and Cellular and Molecular Neuroscience.

Their research topics focus on multiple areas including:

  • Wnt/β-catenin signaling in development and cancer
  • Cellular transport and secretion
  • Epigenetics and DNA Methylation
  • Ion Transport and Channel Regulation
  • Ion Channels and Receptors
  • Ion channel regulation and function
  • Lysosomal Storage Disorders Research

Among their recent papers are:

  • "Emerging links between endosomal pH and cancer," published in 2020 in Cancer and Metastasis Reviews
  • "A DNA nanodevice for mapping sodium at single-organelle resolution," published in 2023 in Nature Biotechnology
  • "Secretory pathway Ca2+-ATPase SPCA2 regulates mitochondrial respiration and DNA damage response through store-independent calcium entry," published in 2022 in Redox Biology
  • "Endosomal Acid-Base Homeostasis in Neurodegenerative Diseases," published in 2020 in Reviews of Physiology, Biochemistry and Pharmacology
  • "Epigenetic Modulation of SPCA2 Reverses Epithelial to Mesenchymal Transition in Breast Cancer Cells," published in 2021 in Cancers

Frequent co-authors collaborating with Rajini Rao include:

  • Monish Ram Makena
  • Myungjun Ko
  • Allatah X. Mekile
  • Donna K. Dang
  • Alfredo Quiñones-Hinojosa

Rajini Rao's work is often published in notable scientific venues such as bioRxiv (Cold Spring Harbor Laboratory), Physiology, Cancer and Metastasis Reviews, Nature Biotechnology, and Redox Biology.

Best Publications

  • The Arabidopsis thaliana proton transporters, AtNhx1 and Avp1, can function in cation detoxification in yeast.

    Roberto A. Gaxiola;Rajini Rao;Amir Sherman;Paula Grisafi

  • Evolutionary origins of eukaryotic sodium/proton exchangers.

    Christopher L. Brett;Mark Donowitz;Rajini Rao

  • The Yeast Endosomal Na+(K+)/H+ Exchanger Nhx1 Regulates Cellular pH to Control Vesicle Trafficking

    Christopher L. Brett;Deepali N. Tukaye;Sanchita Mukherjee;Sanchita Mukherjee;Rajini Rao

  • Mechanism of Antifungal Activity of Terpenoid Phenols Resembles Calcium Stress and Inhibition of the TOR Pathway

    Anjana Rao;Yongqiang Zhang;Sabina Muend;Rajini Rao

  • Intracellular Sequestration of Sodium by a Novel Na+/H+ Exchanger in Yeast Is Enhanced by Mutations in the Plasma Membrane H+-ATPase INSIGHTS INTO MECHANISMS OF SODIUM TOLERANCE

    Richard Nass;Kyle W. Cunningham;Rajini Rao

  • Store-Independent Activation of Orai1 by SPCA2 in Mammary Tumors

    Mingye Feng;Desma M. Grice;Helen M. Faddy;Nguyen Nguyen

  • PMR1, a Ca2+-ATPase in Yeast Golgi, Has Properties Distinct from Sarco/endoplasmic Reticulum and Plasma Membrane Calcium Pumps

    Alexander Sorin;Gisele Rosas;Rajini Rao

  • Novel localization of a Na+/H+ exchanger in a late endosomal compartment of yeast: Implications for vacuole biogenesis

    Richard Nass;Rajini Rao

  • Requirement for ergosterol in V-ATPase function underlies antifungal activity of azole drugs.

    Yong Qiang Zhang;Soledad Gamarra;Guillermo Garcia-Effron;Steven Park

  • Human Na+/H+ exchanger isoform 6 is found in recycling endosomes of cells, not in mitochondria

    Christopher L. Brett;Ying Wei;Mark Donowitz;Rajini Rao

  • Cod1p/Spf1p is a P-type ATPase involved in ER function and Ca2+ homeostasis

    Stephen R. Cronin;Rajini Rao;Randolph Y. Hampton

  • Expression of the yeast plasma membrane [H+]ATPase in secretory vesicles. A new strategy for directed mutagenesis.

    Robert K. Nakamoto;Rajini Rao;Carolyn W. Slayman

  • Antifungal activity of amiodarone is mediated by disruption of calcium homeostasis.

    Soma Sen Gupta;Van Khue Ton;Veronica Beaudry;Samuel Rulli

  • Functional Expression in Yeast of the Human Secretory Pathway Ca2+, Mn2+-ATPase Defective in Hailey-Hailey Disease

    Van Khue Ton;Debjani Mandal;Cordelia Vahadji;Rajini Rao

  • Amyloid clearance defect in ApoE4 astrocytes is reversed by epigenetic correction of endosomal pH.

    Hari Prasad;Rajini Rao

  • Inhibition of sodium/proton exchange by a Rab-GTPase-activating protein regulates endosomal traffic in yeast.

    Rashid Ali;Christopher L. Brett;Sanchita Mukherjee;Rajini Rao

  • A Novel Isoform of the Secretory Pathway Ca2+,Mn2+-ATPase, hSPCA2, Has Unusual Properties and Is Expressed in the Brain

    Minghui Xiang;Deepti Mohamalawari;Rajini Rao

  • Functional expression of heterologous proteins in yeast: insights into Ca2+ signaling and Ca2+-transporting ATPases.

    Van Khue Ton;Rajini Rao

  • The yeast endosomal Na+/H+ exchanger, Nhx1, confers osmotolerance following acute hypertonic shock

    Richard Nass;Rajini Rao

  • Manganese Selectivity of Pmr1, the Yeast Secretory Pathway Ion Pump, Is Defined by Residue Gln783 in Transmembrane Segment 6 RESIDUE Asp778 IS ESSENTIAL FOR CATION TRANSPORT

    Debjani Mandal;Thomas B. Woolf;Rajini Rao

Frequent Co-Authors

Nir Ben-Tal
Nir Ben-Tal Tel Aviv University
Mark Donowitz
Mark Donowitz Johns Hopkins University School of Medicine
Gregory R. Monteith
Gregory R. Monteith University of Queensland
Timothy A. Reinhardt
Timothy A. Reinhardt Agricultural Research Service
Sergio Verjovski-Almeida
Sergio Verjovski-Almeida Universidade de São Paulo
Jun O. Liu
Jun O. Liu Johns Hopkins University School of Medicine
David S. Perlin
David S. Perlin Rutgers, The State University of New Jersey
Steven Park
Steven Park Rutgers, The State University of New Jersey
Etana Padan
Etana Padan Hebrew University of Jerusalem

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