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D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
9906
World Ranking
15685
National Ranking
6535

Overview

Charles J. Malemud is affiliated with Case Western Reserve University in the United States. Their research spans primarily within the field of Medicine, with specific focus on Rheumatology, Oncology, Public Health, Environmental and Occupational Health, Surgery, and Hematology.

The scientist's recent papers demonstrate a focus on autoimmune and inflammatory disorders, cytokine signaling pathways, and diseases such as osteoarthritis and systemic lupus erythematosus. Notable recent publications include:

  • Cardiac Tamponade as Initial Presentation of Systemic Lupus Erythematous in Third-Trimester Pregnancy, 2022, American Journal of Case Reports
  • Tofacitinib Inhibits STAT Phosphorylation and Matrix Metalloproteinase-3, -9 and -13 Production by C28/I2 Human Juvenile Chondrocytes, 2022, Open Access Rheumatology Research and Reviews
  • Role of epigenetics in the pathogenesis and progression of osteoarthritis AK Sorial et al. Multi-tissue epigenetic analysis of the osteoarthritis susceptibility locus mapping to the plectin gene PLEC, 2020, Osteoarthritis and Cartilage
  • Defective Signal Transduction in Osteoarthritic Chondrocytes and Synovial Fibroblasts Should Become a Target for Drug Intervention, 2021, Clinical Immunolgy & Immunotherapy
  • Preface, 2022, Current Rheumatology Reviews

Frequent co-authors who have collaborated with Malemud include:

  • Patrick Yousif
  • Shwetha Sudhakar
  • David E. Blumenthal
  • Jessica R Thorpe
  • Rachel Wilson

The scientist has been regularly published in the following venues:

  • Current Rheumatology Reviews
  • American Journal of Case Reports
  • Open Access Rheumatology Research and Reviews
  • Osteoarthritis and Cartilage
  • Clinical Immunolgy & Immunotherapy

Malemud's research interests encompass several key topics, including:

  • Rheumatoid Arthritis Research and Therapies
  • Cytokine Signaling Pathways and Interactions
  • Osteoarthritis Treatment and Mechanisms
  • Systemic Lupus Erythematosus Research
  • Pregnancy and Medication Impact
  • Eosinophilic Esophagitis
  • Autoimmune and Inflammatory Disorders Research

Best Publications

  • Matrix metalloproteinases (MMPs) in health and disease: an overview.

    Charles J Malemud

  • Biological basis for the use of botanicals in osteoarthritis and rheumatoid arthritis: a review.

    Salahuddin Ahmed;Jeremy Anuntiyo;Charles J. Malemud;Tariq M. Haqqi

  • Pathophysiological mechanisms in osteoarthritis lead to novel therapeutic strategies

    Charles J. Malemud;Najmul Islam;Tariq M. Haqqi

  • The role of the JAK/STAT signal pathway in rheumatoid arthritis.

    Charles J Malemud

  • Genetic linkage of a polymorphism in the type II procollagen gene (COL2A1) to primary osteoarthritis associated with mild chondrodysplasia.

    Robert G. Knowlton;Paul L. Katzenstein;Roland W. Moskowitz;Eric J. Weaver

  • Biologic basis of osteoarthritis: state of the evidence.

    Charles J. Malemud

  • The PI3K/Akt/PTEN/mTOR pathway: a fruitful target for inducing cell death in rheumatoid arthritis?

    Charles J Malemud

  • Neutrophil gelatinase-associated lipocalin is expressed in osteoarthritis and forms a complex with matrix metalloproteinase 9

    Kalpana Gupta;Meenakshi Shukla;Jack B. Cowland;Charles J. Malemud

  • Degradation of cartilage proteoglycan by human leukocyte granule neutral proteases--a model of joint injury. I. Penetration of enzyme into rabbit articular cartilage and release of 35SO4-labeled material from the tissue.

    Aaron Janoff;Gad Feinstein;Charles J. Malemud;JuLus M. Elias

  • Involvement of caspase-3 in epigallocatechin-3-gallate-mediated apoptosis of human chondrosarcoma cells

    Shabana Islam;Najmul Islam;Timothy Kermode;Brian Johnstone

  • Anticytokine therapy for osteoarthritis: evidence to date.

    Charles J. Malemud

  • A POTENT INHIBITOR OF NEURITE OUTGROWTH THAT PREDOMINATES IN THE EXTRACELLULAR MATRIX OF REACTIVE ASTROCYTES

    David R. Canning;Ahmet Höke;Charles J. Malemud;Jerry Silver

  • Inhibition of MMPs and ADAM/ADAMTS.

    Charles J. Malemud

  • Growth hormone, VEGF and FGF: involvement in rheumatoid arthritis.

    Charles J. Malemud

  • Epigallocatechin‐3‐gallate selectively inhibits interleukin‐1 β‐induced activation of mitogen activated protein kinase subgroup c‐Jun N‐terminal kinase in human osteoarthritis chondrocytes

    Rashmi Singh;Salahuddin Ahmed;Charles J. Malemud;Victor M. Goldberg

  • Cytokines as therapeutic targets for osteoarthritis.

    Charles J. Malemud;Charles J. Malemud

  • Extracellular Signal-Regulated Kinase: A Regulator of Cell Growth, Inflammation, Chondrocyte and Bone Cell Receptor-Mediated Gene Expression

    Nathan Lu;Charles J. Malemud

  • Intracellular Signaling Pathways in Rheumatoid Arthritis.

    Charles J Malemud

  • Matrix Metalloproteinases and Synovial Joint Pathology

    Charles J. Malemud

  • Recent advances in neutralizing the IL-6 pathway in arthritis

    Charles Charles J Malemud

Frequent Co-Authors

Victor M. Goldberg
Victor M. Goldberg Case Western Reserve University
Tariq M. Haqqi
Tariq M. Haqqi Northeast Ohio Medical University
David S. Howell
David S. Howell University of Miami
Jerry Silver
Jerry Silver Case Western Reserve University
Johanne Martel-Pelletier
Johanne Martel-Pelletier University of Montreal
Eric Pearlman
Eric Pearlman University of California, Irvine
Ahmet Hoke
Ahmet Hoke Johns Hopkins University
James E. Dennis
James E. Dennis Baylor College of Medicine
Hasan Mukhtar
Hasan Mukhtar University of Wisconsin–Madison
Eben Alsberg
Eben Alsberg University of Illinois at Chicago

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