D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 60 Citations 20,374 167 World Ranking 7725 National Ranking 3522

Research.com Recognitions

Awards & Achievements

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Internal medicine
  • Biochemistry

His scientific interests lie mostly in Cartilage, Osteoarthritis, Biochemistry, Proteoglycan and Anatomy. The study incorporates disciplines such as Collagen network, Metalloproteinase, Enzyme, Molecular biology and Anterior cruciate ligament in addition to Cartilage. David S. Howell has included themes like Inflammation, Internal medicine, Guanidine and Endocrinology in his Osteoarthritis study.

His Internal medicine research integrates issues from Upper limb and Radiography. His Biochemistry research is multidisciplinary, incorporating elements of Calcification and Calcium. His study in Proteoglycan is interdisciplinary in nature, drawing from both Casein and Collagenase.

His most cited work include:

  • Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the knee (5001 citations)
  • The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip. (2083 citations)
  • Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage. (560 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Cartilage, Internal medicine, Endocrinology, Osteoarthritis and Proteoglycan. His Cartilage research incorporates elements of Calcification, Pathology, Glycosaminoglycan and Enzyme. The Internal medicine study combines topics in areas such as Alkaline phosphatase, Pyrophosphate and Cardiology.

His Rickets, Vitamin, Hydroxyproline and Metabolism study in the realm of Endocrinology connects with subjects such as Insulin-like growth factor. His Osteoarthritis study combines topics from a wide range of disciplines, such as Inflammation, Physical therapy, Surgery and Bioinformatics. The Proteoglycan study which covers Articular cartilage that intersects with Anterior cruciate ligament.

He most often published in these fields:

  • Cartilage (49.74%)
  • Internal medicine (33.86%)
  • Endocrinology (28.04%)

What were the highlights of his more recent work (between 1991-2009)?

  • Cartilage (49.74%)
  • Internal medicine (33.86%)
  • Proteoglycan (24.34%)

In recent papers he was focusing on the following fields of study:

David S. Howell mainly investigates Cartilage, Internal medicine, Proteoglycan, Endocrinology and Osteoarthritis. To a larger extent, he studies Anatomy with the aim of understanding Cartilage. Internal medicine and Pathology are frequently intertwined in his study.

As a part of the same scientific family, David S. Howell mostly works in the field of Endocrinology, focusing on Metalloproteinase and, on occasion, Matrix Metalloproteinase 3, Western blot and Tissue inhibitor of metalloproteinase. His Osteoarthritis research incorporates themes from Diagnostic marker and Surgery. His work is dedicated to discovering how Biochemistry, Matrix are connected with Matrix metalloproteinase and other disciplines.

Between 1991 and 2009, his most popular works were:

  • Mechanical Properties of Canine Articular Cartilage Are Significantly Altered Following Transection of the Anterior Cruciate Ligament (201 citations)
  • Mechanical behavior of articular cartilage in shear is altered by transection of the anterior cruciate ligament. (136 citations)
  • Treatment of canine osteoarthritis with insulin-like growth factor-1 (IGF-1) and sodium pentosan polysulfate* (123 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Enzyme
  • Gene

The scientist’s investigation covers issues in Cartilage, Proteoglycan, Matrix metalloproteinase, Articular cartilage and Extracellular matrix. His biological study spans a wide range of topics, including Osteoarthritis, Compression and Joint immobilization. His studies in Osteoarthritis integrate themes in fields like Bone matrix and Crystal deposition.

His work focuses on many connections between Proteoglycan and other disciplines, such as Vesicle, that overlap with his field of interest in Matrix and Molecular biology. His study explores the link between Matrix metalloproteinase and topics such as Collagenase that cross with problems in Therapeutic effect, Urology, Surgery and Cartilage metabolism. His Articular cartilage research is multidisciplinary, relying on both Ultimate tensile strength, Isometric exercise, Anterior cruciate ligament, Anatomy and FEMORAL CONDYLE.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the knee

R. Altman;E. Asch;D. Bloch;G. Bole.
Arthritis & Rheumatism (1986)

7923 Citations

The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip.

R. Altman;G. Alarcón;D. Appelrouth;D. Bloch.
Arthritis & Rheumatism (1990)

2298 Citations

Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage.

David D Dean;J. Martel-Pelletier;J. P. Pelletier;D. S. Howell.
Journal of Clinical Investigation (1989)

771 Citations

Tensile properties of human knee joint cartilage: I. Influence of ionic conditions, weight bearing, and fibrillation on the tensile modulus.

Shaw Akizuki;Van C. Mow;Francisco Müller;Julio C. Pita.
Journal of Orthopaedic Research (1986)

676 Citations

Pathogenesis of osteoarthritis

David S. Howell.
The American Journal of Medicine (1986)

387 Citations

Mechanical Properties of Canine Articular Cartilage Are Significantly Altered Following Transection of the Anterior Cruciate Ligament

L. A. Setton;V. C. Mow;F. J. Müller;J. C. Pita.
Journal of Orthopaedic Research (1994)

295 Citations

Neutral proteases capable of proteoglycan digesting activity in osteoarthritic and normal human articular cartilage

Johanne Martel‐Pelletier;Jean‐Pierre Pelletier;Jean‐Marie Cloutier;David S. Howell.
Arthritis & Rheumatism (1984)

241 Citations

Collagenase and collagenolytic activity in human osteoarthritic cartilage

Jean‐Pierre Pelletier;Johanne Martel‐Pelletier;David S. Howell;Latifa Ghandur‐Mnaymneh.
Arthritis & Rheumatism (1983)

236 Citations

Partition of calcium, phosphate, and protein in the fluid phase aspirated at calcifying sites in epiphyseal cartilage

David S. Howell;Julio C. Pita;Juan F. Marquez;Juan E. Madruga.
Journal of Clinical Investigation (1968)

232 Citations

Metalloproteases of human articular cartilage that digest cartilage proteoglycan at neutral and acid pH.

A I Sapolsky;H Keiser;D S Howell;J F Woessner.
Journal of Clinical Investigation (1976)

217 Citations

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