David S. Howell

Research.com Recognitions

• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians

Overview

Best Publications

• Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the knee

  R. Altman;E. Asch;D. Bloch;G. Bole

  8891
  Citations

• The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip.

  R. Altman;G. Alarcón;D. Appelrouth;D. Bloch

  2581
  Citations

• Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage.

  David D Dean;J. Martel-Pelletier;J. P. Pelletier;D. S. Howell

  779
  Citations

• Tensile properties of human knee joint cartilage: I. Influence of ionic conditions, weight bearing, and fibrillation on the tensile modulus.

  Shaw Akizuki;Van C. Mow;Francisco Müller;Julio C. Pita

  692
  Citations

• Pathogenesis of osteoarthritis

  David S. Howell

  389
  Citations

• Mechanical Properties of Canine Articular Cartilage Are Significantly Altered Following Transection of the Anterior Cruciate Ligament

  L. A. Setton;V. C. Mow;F. J. Müller;J. C. Pita

  302
  Citations

• Neutral proteases capable of proteoglycan digesting activity in osteoarthritic and normal human articular cartilage

  Johanne Martel‐Pelletier;Jean‐Pierre Pelletier;Jean‐Marie Cloutier;David S. Howell

  241
  Citations

• Collagenase and collagenolytic activity in human osteoarthritic cartilage

  Jean‐Pierre Pelletier;Johanne Martel‐Pelletier;David S. Howell;Latifa Ghandur‐Mnaymneh

  237
  Citations

• Partition of calcium, phosphate, and protein in the fluid phase aspirated at calcifying sites in epiphyseal cartilage

  David S. Howell;Julio C. Pita;Juan F. Marquez;Juan E. Madruga

  233
  Citations

• Metalloproteases of human articular cartilage that digest cartilage proteoglycan at neutral and acid pH.

  A I Sapolsky;H Keiser;D S Howell;J F Woessner

  217
  Citations

• Mechanical behavior of articular cartilage in shear is altered by transection of the anterior cruciate ligament.

  L. A. Setton;V. C. Mow;D. S. Howell

  216
  Citations

• Treatment of canine osteoarthritis with insulin-like growth factor-1 (IGF-1) and sodium pentosan polysulfate*

  Richard A. Rogachefsky;David D. Dean;David S. Howell;Roy D. Altman

  188
  Citations

• Collagenolytic activity and collagen matrix breakdown of the articular cartilage in the Pond-Nuki dog model of osteoarthritis.

  Jean‐Pierre ‐P Pelletier;Jean‐Pierre ‐P Pelletier;Johanne Martel‐Pelletier;Johanne Martel‐Pelletier;Roy D. Altman;Latifa Ghandur‐Mnaymneh

  186
  Citations

• Cathepsin D activity in normal and osteoarthritic human cartilage

  Sapolsky Ai;Altman Rd;Howell Ds

  171
  Citations

• Matrix vesicles produced by osteoblast-like cells in culture become significantly enriched in proteoglycan-degrading metalloproteinases after addition of β-Glycerophosphate and ascorbic acid

  David D Dean;Zvi Schwartz;L. Bonewald;O. E. Muniz

  168
  Citations

• Biomechanical and biochemical properties of dog cartilage in experimentally induced osteoarthritis.

  R D Altman;J Tenenbaum;L Latta;W Riskin

  163
  Citations

• Role of synovial membrane inflammation in cartilage matrix breakdown in the Pond-Nuki dog model of osteoarthritis.

  Jean-Pierre Pelletier;Johanne Martel-Pelletier;Latifa Ghandur-Mnaymneh;David S. Howell

  162
  Citations

• Inhibition of calcium phosphate mineral growth by proteoglycan aggregate fractions in a synthetic lymph

  L. A. Cuervo;L. A. Cuervo;J. C. Pita;J. C. Pita;D. S. Howell;D. S. Howell

  157
  Citations

• American rheumatism association

  John L Decker;Thomas E Weiss;David S Howell;Evelyn V Hess

  148
  Citations

• The pathogenesis of osteoarthritis.

  David S. Howell;Asher I. Sapolsky;Julio C. Pita;J.Frederick Woessner

  132
  Citations