World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
92
Citations
21910
World Ranking
2259
National Ranking
160

Overview

Mehdi Shakibaei is affiliated with Ludwig-Maximilians-Universität München in Germany and has an extensive research portfolio spanning medicine and biochemistry. Their work primarily concentrates on molecular biology, cancer research, oncology, molecular medicine, and pharmacology, reflecting a multidisciplinary approach within the biomedical sciences.

The research topics Mehdi Shakibaei focuses on include:

  • Curcumin's Biomedical Applications
  • Sirtuins and Resveratrol in Medicine
  • Cancer, Hypoxia, and Metabolism
  • Natural product bioactivities and synthesis
  • Metabolism, Diabetes, and Cancer
  • Cancer, Lipids, and Metabolism
  • Autophagy in Disease and Therapy

The scientist has contributed to numerous publications in several frequent venues, among which the most notable are:

  • International Journal of Molecular Sciences (7 publications)
  • Cancers (6 publications)
  • Life Sciences (4 publications)
  • Molecules (4 publications)
  • Cancer and Metastasis Reviews (4 publications)

Mehdi Shakibaei's recent papers illustrate a focus on flavonoids and their therapeutic potential, cancer biology, and inflammatory diseases. Selected recent papers include:

  • "Naringenin: A potential flavonoid phytochemical for cancer therapy" (2022, Life Sciences)
  • "Recent Advances in Understanding the Pathogenesis of Rheumatoid Arthritis: New Treatment Strategies" (2021, Cells)
  • "Naringenin Nano-Delivery Systems and Their Therapeutic Applications" (2021, Pharmaceutics)
  • "Flavonoids in Cancer Metastasis" (2020, Cancers)
  • "Flavonoids against the SARS-CoV-2 induced inflammatory storm" (2021, Biomedicine & Pharmacotherapy)

Collaboration is a significant aspect of their work, with frequent coauthors including:

  • Aranka Brockmueller (36 joint publications)
  • Peter Kubatka (20 joint publications)
  • Constanze Buhrmann (19 joint publications)
  • Ajaikumar B. Kunnumakkara (19 joint publications)
  • Dietrich Büsselberg (18 joint publications)

The scientist's main fields of study encompass medicine with 92 publications and biochemistry, genetics, and molecular biology with 82 publications, indicating a solid grounding in both clinical and fundamental biological sciences.

Best Publications

  • Mechanisms of magnesium-stimulated adhesion of osteoblastic cells to commonly used orthopaedic implants.

    H. Zreiqat;C. R. Howlett;A. Zannettino;P. Evans

  • Suppression of NF-kappaB activation by curcumin leads to inhibition of expression of cyclo-oxygenase-2 and matrix metalloproteinase-9 in human articular chondrocytes: Implications for the treatment of osteoarthritis.

    Mehdi Shakibaei;Thilo John;Gundula Schulze-Tanzil;Ingo Lehmann

  • Resveratrol addiction: To die or not to die

    Mehdi Shakibaei;Kuzhuvelil B. Harikumar;Bharat B. Aggarwal

  • Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1β-induced NF-κB-mediated inflammation and apoptosis

    Constanze Csaki;Ali Mobasheri;Mehdi Shakibaei

  • Glycosaminoglycan polymerization may enable osmotically inactive Na+ storage in the skin

    Jens Titze;Mehdi Shakibaei;Markus Schafflhuber;Gundula Schulze-Tanzil

  • Integrins and stretch activated ion channels; putative components of functional cell surface mechanoreceptors in articular chondrocytes.

    A Mobasheri;SD Carter;P Martín-Vasallo;M Shakibaei

  • Redifferentiation of dedifferentiated human chondrocytes in high-density cultures.

    G. Schulze-Tanzil;P. de Souza;H. Villegas Castrejon;T. John

  • Resveratrol-mediated SIRT-1 Interactions With p300 Modulate Receptor Activator of NF-kappaB Ligand (RANKL) Activation of NF-kappaB Signaling and Inhibit Osteoclastogenesis in Bone-Derived Cells

    Mehdi Shakibaei;Constanze Buhrmann;Ali Mobasheri

  • Mesenchymal stem cells in regenerative medicine: opportunities and challenges for articular cartilage and intervertebral disc tissue engineering.

    Stephen M. Richardson;Judith A. Hoyland;Reza Mobasheri;Constanze Csaki

  • Curcumin modulates nuclear factor kappaB (NF-kappaB)-mediated inflammation in human tenocytes in vitro: role of the phosphatidylinositol 3-kinase/Akt pathway.

    Constanze Buhrmann;Ali Mobasheri;Franziska Busch;Constance Aldinger

  • Resveratrol suppresses interleukin-1beta-induced inflammatory signaling and apoptosis in human articular chondrocytes: potential for use as a novel nutraceutical for the treatment of osteoarthritis.

    Mehdi Shakibaei;Constanze Csaki;Simone Nebrich;Ali Mobasheri

  • Curcumin Enhances the Effect of Chemotherapy against Colorectal Cancer Cells by Inhibition of NF-κB and Src Protein Kinase Signaling Pathways

    Mehdi Shakibaei;Ali Mobasheri;Cora Lueders;Franziska Busch

  • Biological actions of curcumin on articular chondrocytes

    Y. Henrotin;A.L. Clutterbuck;D. Allaway;E.M. Lodwig

  • Regulation of inflammation signalling by resveratrol in human chondrocytes in vitro.

    Constanze Csaki;Nerses Keshishzadeh;Karoline Fischer;Mehdi Shakibaei

  • Curcumin mediates chemosensitization to 5-fluorouracil through miRNA-induced suppression of epithelial-to-mesenchymal transition in chemoresistant colorectal cancer.

    Shusuke Toden;Yoshinaga Okugawa;Thomas Jascur;Dominik Wodarz

  • Resveratrol mediated modulation of Sirt-1/Runx2 promotes osteogenic differentiation of mesenchymal stem cells: potential role of Runx2 deacetylation.

    Mehdi Shakibaei;Parviz Shayan;Franziska Busch;Constance Aldinger

  • IGF-1 and PDGF-bb suppress IL-1β-induced cartilage degradation through down-regulation of NF-κB signaling: involvement of Src/PI-3K/AKT pathway.

    Azadeh Montaseri;Franziska Busch;Ali Mobasheri;Constanze Buhrmann

  • Chondrogenesis, osteogenesis and adipogenesis of canine mesenchymal stem cells: a biochemical, morphological and ultrastructural study

    C. Csaki;U. Matis;A. Mobasheri;H. Ye

  • Subcellular Pathways of β-Endorphin Synthesis, Processing, and Release from Immunocytes in Inflammatory Pain

    Shaaban A Mousa;Mehdi Shakibaei;Nicolle Sitte;Michael Schäfer

  • Simulated microgravity alters differentiation and increases apoptosis in human follicular thyroid carcinoma cells

    Daniela Grimm;Johann Bauer;Peter Kossmehl;Mehdi Shakibaei

Frequent Co-Authors

Ali Mobasheri
Ali Mobasheri University of Oulu
Daniela Grimm
Daniela Grimm Otto-von-Guericke University Magdeburg
Martin Paul
Martin Paul Ruhr University Bochum
Stephen M. Richardson
Stephen M. Richardson University of Manchester
Judith A. Hoyland
Judith A. Hoyland University of Manchester
Carolyn A. Bondy
Carolyn A. Bondy National Institutes of Health
Ajay Goel
Ajay Goel City Of Hope National Medical Center
Kelle H. Moley
Kelle H. Moley Washington University in St. Louis
Ajaikumar B. Kunnumakkara
Ajaikumar B. Kunnumakkara Indian Institute of Technology Guwahati
Stuart D. Carter
Stuart D. Carter University of Liverpool

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