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Biology and Biochemistry

D-Index
66
Citations
11473
World Ranking
8891
National Ranking
648

Overview

Daniela Grimm is affiliated with Otto-von-Guericke University Magdeburg in Germany. Their research primarily focuses on the biological and medical effects of spaceflight, with a particular interest in molecular and cellular physiology under conditions such as microgravity and altered environmental stresses.

The main fields of study in their work include Medicine and Biochemistry, Genetics, and Molecular Biology. Within these fields, the notable subfields of study are Physiology, Pulmonary and Respiratory Medicine, Aerospace Engineering, Cardiology and Cardiovascular Medicine, and Endocrinology, Diabetes and Metabolism.

The topics covered by their research include Spaceflight effects on biology, Space Exploration and Technology, Genetics, Aging, and Longevity in Model Organisms, High Altitude and Hypoxia, Radiation Therapy and Dosimetry, Space Science and Extraterrestrial Life, and Cancer, Hypoxia, and Metabolism.

They have contributed to several recent publications, illustrating the direction and impact of their research agenda. Selected papers include:

  • Endothelin Receptor Antagonists: Status Quo and Future Perspectives for Targeted Therapy, 2020, Journal of Clinical Medicine
  • Influence of Microgravity on Apoptosis in Cells, Tissues, and Other Systems In Vivo and In Vitro, 2020, International Journal of Molecular Sciences
  • Role of Apoptosis in Wound Healing and Apoptosis Alterations in Microgravity, 2021, Frontiers in Bioengineering and Biotechnology
  • The Cardiovascular System in Space: Focus on In Vivo and In Vitro Studies, 2021, Biomedicines
  • The effects of microgravity on differentiation and cell growth in stem cells and cancer stem cells, 2020, Stem Cells Translational Medicine

Their frequent co-authors include Marcus Krüger, Markus Wehland, Manfred Infanger, Thomas J. Corydon, and Jayashree Sahana, reflecting a collaborative network within their research community.

Their work has been published predominantly in journals such as the International Journal of Molecular Sciences, Biomolecules, Cells, npj Microgravity, and Biomedicines, which indicates a strong presence in publications focused on molecular sciences and biomedical applications relevant to space biology and related fields.

Best Publications

  • The role of SOX family members in solid tumours and metastasis.

    Daniela Grimm;Daniela Grimm;Johann Bauer;Petra Wise;Marcus Krüger

  • Development of heart failure following isoproterenol administration in the rat: role of the renin–angiotensin system

    Daniela Grimm;Dietmar Elsner;Heribert Schunkert;Michael Pfeifer

  • The impact of microgravity on bone in humans.

    Daniela Grimm;Jirka Grosse;Markus Wehland;Vivek Mann

  • Simulated microgravity alters differentiation and increases apoptosis in human follicular thyroid carcinoma cells

    Daniela Grimm;Johann Bauer;Peter Kossmehl;Mehdi Shakibaei

  • Simulated Microgravity: Critical Review on the Use of Random Positioning Machines for Mammalian Cell Culture

    Simon L. Wuest;Stéphane Richard;Sascha Kopp;Daniela Grimm

  • Blockade of the Renin-Angiotensin System in Cardiac Pressure-Overload Hypertrophy in Rats

    Günter Bruckschlegel;Stephan R. Holmer;Karin Jandeleit;Daniela Grimm

  • The effects of weightlessness on the human organism and mammalian cells.

    J. Pietsch;J. Bauer;M. Egli;M. Infanger

  • Glucose transporter 1 gene expression is related to thyroid neoplasms with an unfavorable prognosis: an immunohistochemical study.

    Johann Schönberger;J. Rüschoff;Daniela Grimm;Jörg Marienhagen

  • Induction of three-dimensional assembly and increase in apoptosis of human endothelial cells by simulated microgravity: impact of vascular endothelial growth factor.

    M. Infanger;P. Kossmehl;M. Shakibaei;M. Shakibaei;S. Baatout

  • Evidence for a Vasopressin System in the Rat Heart

    Harald Hupf;Daniela Grimm;Günter A. J. Riegger;Heribert Schunkert

  • Growing tissues in real and simulated microgravity: new methods for tissue engineering.

    Daniela Grimm;Markus Wehland;Jessica Pietsch;Ganna Aleshcheva

  • Differential gene expression profile and altered cytokine secretion of thyroid cancer cells in space

    Xiao Ma;Jessica Pietsch;Markus Wehland;Herbert Schulz

  • Simulated weightlessness changes the cytoskeleton and extracellular matrix proteins in papillary thyroid carcinoma cells

    Manfred Infanger;Peter Kossmehl;Mehdi Shakibaei;Mehdi Shakibaei;Johann Bauer

  • Alterations of the cytoskeleton in human cells in space proved by life-cell imaging.

    Thomas J. Corydon;Sascha Kopp;Markus Wehland;Markus Braun

  • Modeled gravitational unloading induced downregulation of endothelin-1 in human endothelial cells.

    Manfred Infanger;Claudia Ulbrich;Sarah Baatout;Markus Wehland

  • Differential gene regulation under altered gravity conditions in follicular thyroid cancer cells: relationship between the extracellular matrix and the cytoskeleton

    C. Ulbrich;J. Pietsch;J. Grosse;M. Wehland

  • Spheroid formation of human thyroid cancer cells in an automated culturing system during the Shenzhou-8 Space mission.

    Jessica Pietsch;Xiao Ma;Markus Wehland;Ganna Aleshcheva

  • The impact of simulated and real microgravity on bone cells and mesenchymal stem cells

    Claudia Ulbrich;Markus Wehland;Jessica Pietsch;Ganna Aleshcheva

  • Vascular endothelial growth factor serum level is strongly enhanced after burn injury and correlated with local and general tissue edema

    Manfred Infanger;Oliver Schmidt;Peter Kossmehl;Sibylle Grad

  • Weightlessness induced apoptosis in normal thyroid cells and papillary thyroid carcinoma cells via extrinsic and intrinsic pathways

    Peter Kossmehl;Mehdi Shakibaei;Augusto Cogoli;Manfred Infanger

Frequent Co-Authors

Thomas J. Corydon
Thomas J. Corydon Aarhus University
Martin Paul
Martin Paul Ruhr University Bochum
Mehdi Shakibaei
Mehdi Shakibaei Ludwig-Maximilians-Universität München
Heribert Schunkert
Heribert Schunkert Technical University of Munich
Norbert Hubner
Norbert Hubner Max Delbrück Center for Molecular Medicine
Albert Sickmann
Albert Sickmann Leibniz Institute for Neurobiology
Kathrin Saar
Kathrin Saar Max Delbrück Center for Molecular Medicine
Herbert Schulz
Herbert Schulz University of Cologne
Christian Betzel
Christian Betzel Universität Hamburg
Oliver Ullrich
Oliver Ullrich University of Zurich

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