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Biology and Biochemistry

D-Index
46
Citations
10719
World Ranking
18855
National Ranking
1292

Overview

Kathrin Saar is affiliated with the Max Delbrück Center for Molecular Medicine in Germany. Their research encompasses multiple fields within medicine and molecular biology, with a focus on immunology, infectious diseases, cancer research, and epidemiology. Saar's work often intersects with key topics such as COVID-19 clinical research, SARS-CoV-2 studies, atherosclerosis and cardiovascular diseases, adipokines related to inflammation and metabolic disorders, cancer-related molecular mechanisms, and microRNA in disease regulation.

Their recent publications include studies in notable scientific journals and address diverse aspects of molecular and clinical research. These publications are:

  • "Self-sustaining IL-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19" (2021), published in JCI Insight
  • "Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice" (2020), published in Proceedings of the National Academy of Sciences
  • "Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection" (2022), published in Nature Communications
  • "Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes" (2024), published in Nature Medicine
  • "Statin-induced myopathic changes in primary human muscle cells and reversal by a prostaglandin F2 alpha analogue" (2020), published in Scientific Reports

Saar has collaborated frequently with a number of co-authors, including:

  • Norbert Hübner (11 joint publications)
  • Oliver Popp (6 joint publications)
  • Rainer Kaiser (5 joint publications)
  • Kami Pekayvaz (5 joint publications)
  • Markus Joppich (5 joint publications)

Their work has appeared repeatedly in several publication venues, underscoring a steady involvement in key outlets for biomedical research. These include:

  • Scientific Reports (3 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (2 publications)
  • JCI Insight (1 publication)
  • Nature Medicine (1 publication)
  • Proceedings of the National Academy of Sciences (1 publication)

The main fields of study associated with Saar involve Medicine broadly, supported by a strong foundation in Biochemistry, Genetics, and Molecular Biology. Their contributions span molecular biology techniques and applications, with emphases on immunological responses and infectious diseases, alongside cancer research and epidemiological insights.

Best Publications

  • Febrile seizures and generalized epilepsy associated with a mutation in the Na+-channel beta1 subunit gene SCN1B.

    Robyn H. Wallace;Dao W. Wang;Rita Singh;Rita Singh;Ingrid E. Scheffer;Ingrid E. Scheffer;Ingrid E. Scheffer

  • Nibrin, a Novel DNA Double-Strand Break Repair Protein, Is Mutated in Nijmegen Breakage Syndrome

    Raymonda Varon;Christine Vissinga;Matthias Platzer;Karen M Cerosaletti

  • RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing

    Wei Guo;Sebastian Schafer;Marion L Greaser;Michael H Radke

  • IL-11 is a crucial determinant of cardiovascular fibrosis

    Sebastian Schafer;Sivakumar Viswanathan;Anissa A Widjaja;Wei-Wen Lim

  • A Genome-wide Search for Linkage to Asthma

    Matthias Wjst;Guido Fischer;Thomas Immervoll;Martin Jung

  • Progress and prospects in rat genetics: a community view.

    Timothy J Aitman;John K Critser;Edwin Cuppen;Anna Dominiczak

  • A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

    Matthias Heinig;Enrico Petretto;Chris Wallace;Leonardo Bottolo

  • Splitting Schizophrenia: Periodic Catatonia–Susceptibility Locus on Chromosome 15q15

    Gerald Stöber;Kathrin Saar;Franz Rüschendorf;Jobst Meyer

  • Distribution and functional impact of DNA copy number variation in the rat

    Victor Guryev;Kathrin Saar;Tatjana Adamovic;Mark Verheul

  • Genome search for susceptibility loci of common idiopathic generalised epilepsies

    Thomas Sander;Herbert Schulz;Kathrin Saar;Elena Gennaro

  • SNP and haplotype mapping for genetic analysis in the rat

    Kathrin Saar;Alfred Beck;Marie-Thérèse Bihoreau;Ewan Birney

  • Genome-wide analysis indicates more Asian than Melanesian ancestry of Polynesians.

    Manfred Kayser;Oscar Lao;Kathrin Saar;Silke Brauer

  • Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease.

    Jan Monti;Judith Fischer;Svetlana Paskas;Matthias Heinig;Matthias Heinig

  • Combined sequence-based and genetic mapping analysis of complex traits in outbred rats

    A. Baud;R. Hermsen;V. Guryev;P. Stridh

  • A genome-wide scan for attention-deficit/hyperactivity disorder in 155 German sib-pairs

    J Hebebrand;A Dempfle;K Saar;H Thiele

  • PTHR1 Loss-of-Function Mutations in Familial, Nonsyndromic Primary Failure of Tooth Eruption

    Eva Decker;Eva Decker;Angelika Stellzig-Eisenhauer;Britta S. Fiebig;Christiane Rau

  • Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat.

    Santosh S. Atanur;Ana Garcia Diaz;Klio Maratou;Allison Sarkis

  • Homozygosity mapping in families with Joubert syndrome identifies a locus on chromosome 9q34.3 and evidence for genetic heterogeneity.

    Kathrin Saar;Lihadh Al-Gazali;László Sztriha;Franz Rueschendorf

  • The gene for the ataxia-telangiectasia variant, Nijmegen breakage syndrome, maps to a 1-cM interval on chromosome 8q21.

    K Saar;K H Chrzanowska;M Stumm;M Jung

  • Gene Localization for an Autosomal Dominant Familial Periodic Fever to 12p13

    John Mulley;John Mulley;Kathrin Saar;Gerry Hewitt;Franz Rüschendorf

Frequent Co-Authors

Norbert Hubner
Norbert Hubner Max Delbrück Center for Molecular Medicine
André Reis
André Reis University of Erlangen-Nuremberg
Franz Rüschendorf
Franz Rüschendorf Max Delbrück Center for Molecular Medicine
Thomas F. Wienker
Thomas F. Wienker Max Planck Society
Herbert Schulz
Herbert Schulz University of Cologne
Michal Pravenec
Michal Pravenec Czech Academy of Sciences
Enrico Petretto
Enrico Petretto Duke NUS Graduate Medical School
Daniela Grimm
Daniela Grimm Otto-von-Guericke University Magdeburg
Timothy J. Aitman
Timothy J. Aitman University of Edinburgh
Edwin Cuppen
Edwin Cuppen Utrecht University

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