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Microbiology

D-Index
107
Citations
44749
World Ranking
279
National Ranking
128

Overview

Mahmoud A. Ghannoum is affiliated with Case Western Reserve University in the United States. Their research primarily focuses on medicine and intersects with biochemistry, genetics, and molecular biology.

The scientist has contributed extensively to topics such as antifungal resistance and susceptibility, gut microbiota and health, fungal infections and studies, nail diseases and treatments, probiotics and fermented foods, plant pathogens and fungal diseases, and bladder and urothelial cancer treatments.

Notable recent publications include:

  • Ibrexafungerp: A Novel Oral Triterpenoid Antifungal in Development for the Treatment of Candida auris Infections, 2020, published in Antibiotics
  • Ibrexafungerp Versus Placebo for Vulvovaginal Candidiasis Treatment: A Phase 3, Randomized, Controlled Superiority Trial (VANISH 303), 2021, Clinical Infectious Diseases
  • Phase 3 study evaluating the safety and efficacy of oteseconazole in the treatment of recurrent vulvovaginal candidiasis and acute vulvovaginal candidiasis infections, 2022, American Journal of Obstetrics and Gynecology
  • Update on the Pathogenesis, Virulence, and Treatment of Candida auris, 2022, Pathogens and Immunity
  • A Randomized Phase 2 Study of VT-1161 for the Treatment of Acute Vulvovaginal Candidiasis, 2020, Clinical Infectious Diseases

Frequent co-authors in Mahmoud A. Ghannoum's work include Thomas S. McCormick, Ahmed Gamal, Mauricio Retuerto, Laura Bukavina, and Luca Di Martino.

Research has been published predominantly in several venues, with the most frequent being:

  • Antimicrobial Agents and Chemotherapy
  • SKIN The Journal of Cutaneous Medicine
  • Open Forum Infectious Diseases
  • Antibiotics
  • Gastroenterology

The core subfields of study encompass epidemiology, infectious diseases, molecular biology, surgery, and food science, reflecting a broad and interdisciplinary approach to medical research and microbial studies.

Best Publications

  • Antifungal Agents: Mode of Action, Mechanisms of Resistance, and Correlation of These Mechanisms with Bacterial Resistance

    Mahmoud A. Ghannoum;Louis B. Rice

  • Biofilm formation by the fungal pathogen Candida albicans: development, architecture, and drug resistance.

    Jyotsna Chandra;Duncan M. Kuhn;Pranab K. Mukherjee;Lois L. Hoyer

  • Characterization of the Oral Fungal Microbiome (Mycobiome) in Healthy Individuals

    Mahmoud A Ghannoum;Richard J. Jurevic;Pranab Kumar Mukherjee;Fan Cui

  • Development of Interpretive Breakpoints for Antifungal Susceptibility Testing: Conceptual Framework and Analysis of In Vitro-In Vivo Correlation Data for Fluconazole, Itraconazole, and Candida Infections

    John H. Rex;Michael A. Pfaller;John N. Galgiani;Marilyn S. Bartlett

  • Potential Role of Phospholipases in Virulence and Fungal Pathogenesis

    Mahmoud A. Ghannoum

  • Antifungal Susceptibility of Candida Biofilms: Unique Efficacy of Amphotericin B Lipid Formulations and Echinocandins

    D. M. Kuhn;T. George;J. Chandra;P. K. Mukherjee

  • Resistance of Candida to azoles and echinocandins worldwide.

    Unknown

  • A large-scale North American study of fungal isolates from nails: The frequency of onychomycosis, fungal distribution, and antifungal susceptibility patterns

    M. A. Ghannoum;R. A. Hajjeh;R. Scher;N. Konnikov

  • Antifungal Resistance of Candidal Biofilms Formed on Denture Acrylic in vitro

    J. Chandra;Pranab Kumar Mukherjee;S. D. Leidich;F. F. Faddoul

  • Comparison of biofilms formed by Candida albicans and Candida parapsilosis on bioprosthetic surfaces.

    D. M. Kuhn;J. Chandra;J. Chandra;Pranab Kumar Mukherjee;Pranab Kumar Mukherjee;Mahmoud A Ghannoum;Mahmoud A Ghannoum

  • Mechanism of Fluconazole Resistance in Candida albicans Biofilms: Phase-Specific Role of Efflux Pumps and Membrane Sterols

    Pranab K. Mukherjee;Jyotsna Chandra;Duncan M. Kuhn;Mahmoud A. Ghannoum

  • Antifungal Susceptibility Testing: Practical Aspects and Current Challenges

    John H. Rex;Michael A. Pfaller;Thomas J. Walsh;Vishnu Chaturvedi

  • The Gut Microbiome as a Major Regulator of the Gut-Skin Axis

    Iman Salem;Amy Ramser;Nancy Isham;Mahmoud A Ghannoum;Mahmoud A Ghannoum

  • Indoor Mold, Toxigenic Fungi, and Stachybotrys chartarum: Infectious Disease Perspective

    D. M. Kuhn;M. A. Ghannoum

  • Evidence implicating phospholipase as a virulence factor of Candida albicans

    AS Ibrahim;F Mirbod;SG Filler;Y Banno

  • Extracellular phospholipase activity is a virulence factor for Cryptococcus neoformans.

    Gary M. Cox;Henry C. McDade;Sharon C. A. Chen;Stephanie C. Tucker

  • Bacteriome and Mycobiome Interactions Underscore Microbial Dysbiosis in Familial Crohn’s Disease

    G. Hoarau;Pranab Kumar Mukherjee;C. Gower-Rousseau;C. Hager

  • Zygomycosis: the re-emerging fungal infection.

    M. Chayakulkeeree;M. Chayakulkeeree;M. A. Ghannoum;J. R. Perfect

  • The Emerging Pathogen Candida auris: Growth Phenotype, Virulence Factors, Activity of Antifungals, and Effect of SCY-078, a Novel Glucan Synthesis Inhibitor, on Growth Morphology and Biofilm Formation

    Emily Larkin;Christopher Hager;Jyotsna Chandra;Pranab Kumar Mukherjee

  • Uses and Limitations of the XTT Assay in Studies of Candida Growth and Metabolism

    D. M. Kuhn;M. Balkis;J. Chandra;P. K. Mukherjee

  • International Conference for the Development of a Consensus on the Management and Prevention of Severe Candidal Infections.

    J E Jr Edwards;G. P. Bodey;R. A. Bowden;T. Buchner

  • Potential Role of Phospholipases in Virulence and Fungal Pathogenesis

    Unknown

Frequent Co-Authors

Pranab K. Mukherjee
Pranab K. Mukherjee Louisiana State University
Thomas S. McCormick
Thomas S. McCormick Case Western Reserve University
Thomas J. Walsh
Thomas J. Walsh Weill Cornell Medicine
Ashraf S. Ibrahim
Ashraf S. Ibrahim University of California, Los Angeles
Vishnu Chaturvedi
Vishnu Chaturvedi New York State Department of Health
Michael G. Rinaldi
Michael G. Rinaldi The University of Texas Health Science Center at San Antonio
John E. Edwards
John E. Edwards University of California, Los Angeles
Scott G. Filler
Scott G. Filler University of California, Los Angeles
Shawn A. Messer
Shawn A. Messer Oregon Health & Science University
Michael A. Pfaller
Michael A. Pfaller JMI Laboratories

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