World's Best Scientists 2026 revealed!
Deepak Cyril D'Souza

Deepak Cyril D'Souza

D-Index & Metrics

Neuroscience

D-Index
70
Citations
18324
World Ranking
2506
National Ranking
1189

Social Sciences and Humanities

D-Index
70
Citations
18248
World Ranking
777
National Ranking
370

Medicine

D-Index
70
Citations
18324
World Ranking
20089
National Ranking
10001

Overview

Deepak Cyril D'Souza is affiliated with Yale University in the United States. Their research primarily spans the fields of Medicine and Neuroscience, with a focus on several subfields including Pharmacology, Cognitive Neuroscience, Clinical Psychology, Cellular and Molecular Neuroscience, and Psychiatry and Mental Health.

The scientist's work engages deeply with topics related to Cannabis and Cannabinoid Research, Psychedelics and Drug Studies, Tryptophan and brain disorders, Chemical synthesis and alkaloids, Neurotransmitter Receptor Influence on Behavior, Functional Brain Connectivity Studies, and Treatment of Major Depression.

Recent publications include:

  • Psychiatric symptoms caused by cannabis constituents: a systematic review and meta-analysis (2020, The Lancet Psychiatry)
  • Modulation of the antidepressant effects of ketamine by the mTORC1 inhibitor rapamycin (2020, Neuropsychopharmacology)
  • Association of Ketamine With Psychiatric Symptoms and Implications for Its Therapeutic Use and for Understanding Schizophrenia (2020, JAMA Network Open)
  • Exploratory study of the dose-related safety, tolerability, and efficacy of dimethyltryptamine (DMT) in healthy volunteers and major depressive disorder (2022, Neuropsychopharmacology)
  • Exploratory Controlled Study of the Migraine-Suppressing Effects of Psilocybin (2020, Neurotherapeutics)

Frequent co-authors contributing to research alongside Deepak Cyril D'Souza include Mohini Ranganathan, Patrick D. Skosnik, Suhas Ganesh, Rajiv Radhakrishnan, and John H. Krystal.

Publications are often found in venues such as bioRxiv (Cold Spring Harbor Laboratory), Psychopharmacology, Neuropsychopharmacology, Biological Psychiatry, and the Journal of Psychopharmacology.

Best Publications

  • The psychotomimetic effects of intravenous Delta-9-tetrahydrocannabinol in healthy individuals: Implications for psychosis

    Deepak Cyril D'Souza;Edward Perry;Lisa MacDougall;Yola Ammerman

  • Delta-9-tetrahydrocannabinol effects in schizophrenia: implications for cognition, psychosis, and addiction.

    Deepak Cyril D’Souza;Walid Michel Abi-Saab;Walid Michel Abi-Saab;Steven Madonick;Kimberlee Forselius-Bielen

  • The acute effects of cannabinoids on memory in humans: a review

    Mohini Ranganathan;Deepak Cyril D’Souza

  • NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development.

    John H. Krystal;D. Cyril D'Souza;Daniel Mathalon;Edward Perry

  • Deficits in Prefrontal Cortical and Extrastriatal Dopamine Release in Schizophrenia: A Positron Emission Tomographic Functional Magnetic Resonance Imaging Study

    Mark Slifstein;Mark Slifstein;Elsmarieke van de Giessen;Elsmarieke van de Giessen;Jared Van Snellenberg;Jared Van Snellenberg;Judy L. Thompson;Judy L. Thompson;Judy L. Thompson

  • Gone to Pot - A Review of the Association between Cannabis and Psychosis.

    Rajiv Radhakrishnan;Samuel T. Wilkinson;Deepak Cyril D’Souza

  • Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group II metabotropic glutamate receptor agonist, LY354740, in healthy human subjects

    John H. Krystal;Walid Abi-Saab;Edward Perry;D. Cyril D’Souza

  • Clinical significance of neurological soft signs in schizophrenia: Factor analysis of the Neurological Evaluation Scale

    R. Andrew Sewell;Edward B. Perry;Laurence P. Karper;Morris D. Bell

  • Comparative and Interactive Human Psychopharmacologic Effects of Ketamine and Amphetamine: Implications for Glutamatergic and Dopaminergic Model Psychoses and Cognitive Function

    John H. Krystal;Edward B. Perry;Edward B. Perry;Ralitza Gueorguieva;Aysenil Belger

  • Cannabis and psychosis/schizophrenia: human studies

    Deepak Cyril D’Souza;Richard Andrew Sewell;Mohini Ranganathan

  • N-methyl-D-aspartate glutamate receptors and alcoholism: reward, dependence, treatment, and vulnerability.

    John H. Krystal;Ismene L. Petrakis;Graeme Mason;Louis Trevisan

  • NMDA agonists and antagonists as probes of glutamatergic dysfunction and pharmacotherapies in neuropsychiatric disorders

    John H. Krystal;D. Cyril D'Souza;Ismene L. Petrakis;Aysenil Belger

  • Blunted psychotomimetic and amnestic effects of delta-9-tetrahydrocannabinol in frequent users of cannabis.

    Deepak Cyril D'Souza;Mohini Ranganathan;Gabriel Braley;Ralitza Gueorguieva

  • Spicing things up: synthetic cannabinoids

    Max Spaderna;Peter H. Addy;Deepak Cyril D’Souza

  • Nicotine effects on brain function and functional connectivity in schizophrenia.

    Leslie K Jacobsen;D.Cyril D'Souza;W.Einar Mencl;Kenneth R Pugh

  • Interactive effects of subanesthetic ketamine and haloperidol in healthy humans.

    Krystal Jh;D'Souza Dc;Karper Lp;Bennett A

  • The NMDA antagonist model for schizophrenia: promise and pitfalls.

    W. M. Abi-Saab;D. C. D'Souza;D. C. D'Souza;B. Moghaddam;J. H. Krystal;J. H. Krystal

  • Relationship of resting brain hyperconnectivity and schizophrenia-like symptoms produced by the NMDA receptor antagonist ketamine in humans

    Naomi R. Driesen;Gregory McCarthy;Zubin Bhagwagar;Zubin Bhagwagar;Michael Bloch

  • Marijuana Legalization: Impact on Physicians and Public Health

    Samuel T. Wilkinson;Stephanie Yarnell;Rajiv Radhakrishnan;Samuel A. Ball;Samuel A. Ball

  • The effects of cannabidiol (CBD) on cognition and symptoms in outpatients with chronic schizophrenia a randomized placebo controlled trial.

    Douglas L. Boggs;Toral Surti;Aarti Gupta;Swapnil Gupta

  • Interactive effects of subanesthetic ketamine and subhypnotic lorazepam in humans.

    Krystal Jh;Karper Lp;Bennett A;D'Souza Dc

Frequent Co-Authors

John H. Krystal
John H. Krystal Yale University
Brian Pittman
Brian Pittman Yale University
Daniel H. Mathalon
Daniel H. Mathalon University of California, San Francisco
Richard E. Carson
Richard E. Carson Yale University
Yiyun Huang
Yiyun Huang Yale University
Thomas B. Cooper
Thomas B. Cooper Columbia University
Anissa Abi-Dargham
Anissa Abi-Dargham Stony Brook University
Chadi G. Abdallah
Chadi G. Abdallah Baylor College of Medicine
Nabeel Nabulsi
Nabeel Nabulsi Yale University
Steven M. Southwick
Steven M. Southwick Yale University

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