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Medicine

D-Index
84
Citations
28472
World Ranking
15005
National Ranking
212

Overview

Alberto Lleó is affiliated with the Hospital de la Santa Creu i Sant Pau in Spain. Their research primarily focuses on various aspects of medicine, with strong involvement in subfields such as physiology, psychiatry and mental health, neurology, molecular biology, and public health, environmental and occupational health.

The core topics of their work include Alzheimer's disease research and treatments, dementia and cognitive impairment research, Down syndrome and intellectual disability research, Parkinson's disease mechanisms and treatments, amyotrophic lateral sclerosis research, frailty in older adults, and chronic disease management strategies.

They have contributed to a number of recent scientific papers, including the following:

  • Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology, 2024, JAMA Neurology
  • A multicentre validation study of the diagnostic value of plasma neurofilament light, 2021, Nature Communications
  • Clinical and biomarker changes of Alzheimer's disease in adults with Down syndrome: a cross-sectional study, 2020, The Lancet
  • APOE4 homozygosity represents a distinct genetic form of Alzheimer's disease, 2024, Nature Medicine
  • Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum, 2022, JAMA Neurology

Lleó collaborates frequently with several researchers, including Juan Fortea, Daniel Alcolea, María Carmona-Iragui, Isabel Barroeta, and Laura Videla, reflecting a consistent network of co-authorship across multiple studies.

Their publications are commonly found in journals known for neurological and Alzheimer's disease research, including:

  • Alzheimer's & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neurology
  • Alzheimer's Research & Therapy
  • Journal of Alzheimer's Disease

Alberto Lleó has a substantial body of work totaling 473 publications in medicine. This includes 152 focused on physiology, 117 on psychiatry and mental health, 103 on neurology, 84 on molecular biology, and 42 that intersect with public health concerns.

Best Publications

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.

    Gernot Kleinberger;Yoshinori Yamanishi;Marc Suárez-Calvet;Eva Czirr

  • Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis.

    Rik Ossenkoppele;Willemijn J Jansen;Gil D Rabinovici;Dirk L Knol

  • sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers

    Marc Suárez-Calvet;Marc Suárez-Calvet;Gernot Kleinberger;Miguel Ángel Araque Caballero;Matthias Brendel

  • A multicentre validation study of the diagnostic value of plasma neurofilament light.

    Nicholas J. Ashton;Shorena Janelidze;Ahmad Al Khleifat;Antoine Leuzy

  • Current Pharmacotherapy for Alzheimer's Disease

    A. Lleó;S.M. Greenberg;J.H. Growdon

  • Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

    Ruth Chia;Marya S. Sabir;Sara Bandres-Ciga

  • Frontotemporal dementia and its subtypes: a genome-wide association study

    Raffaele Ferrari;Raffaele Ferrari;Dena G Hernandez;Dena G Hernandez;Michael A Nalls;Jonathan D Rohrer

  • A novel GSK-3β inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo

    Lídia Serenó;Mireia Coma;M. Rodríguez;P. Sánchez-Ferrer

  • CSF biomarker variability in the Alzheimer's Association quality control program

    Niklas Mattsson;Niklas Mattsson;Ulf Andreasson;Staffan Persson;Maria C. Carrillo

  • Consensus guidelines for lumbar puncture in patients with neurological diseases

    Sebastiaan Engelborghs;Ellis Niemantsverdriet;Hanne Struyfs;Kaj Blennow

  • Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry

    Piotr Lewczuk;Peter Riederer;Sid E. O’Bryant;Marcel M. Verbeek

  • A novel Alzheimer disease locus located near the gene encoding tau protein

    G. Jun;C. A. Ibrahim-Verbaas;M. Vronskaya;J-C Lambert;J-C Lambert;J-C Lambert

  • Clinical and biomarker changes of Alzheimer's disease in adults with Down syndrome: a cross-sectional study

    Juan Fortea;Eduard Vilaplana;Maria Carmona-Iragui;Bessy Benejam

  • Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

    Rita Guerreiro;Rita Guerreiro;Owen A Ross;Celia Kun-Rodrigues;Dena G Hernandez;Dena G Hernandez

  • Nonsteroidal anti-inflammatory drugs lower Abeta42 and change presenilin 1 conformation.

    Alberto Lleó;Oksana Berezovska;Lauren Herl;Susan Raju

  • Performance and complications of lumbar puncture in memory clinics: Results of the multicenter lumbar puncture feasibility study

    Flora H. Duits;Pablo Martinez-Lage;Claire Paquet;Claire Paquet;Sebastiaan Engelborghs

  • Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP

    Rita Joao Guerreiro;Miquel Baquero;Rafael Blesa;Mercè Boada

Frequent Co-Authors

Juan Fortea
Juan Fortea Hospital de Sant Pau
Henrik Zetterberg
Henrik Zetterberg University of Gothenburg
Kaj Blennow
Kaj Blennow University of Gothenburg
Pieter Jelle Visser
Pieter Jelle Visser Amsterdam University Medical Centers
Sebastiaan Engelborghs
Sebastiaan Engelborghs University of Antwerp
Philip Scheltens
Philip Scheltens Amsterdam UMC
Pau Pastor
Pau Pastor University of Navarra
Lars Bertram
Lars Bertram University of Lübeck

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