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Rik Vandenberghe

Rik Vandenberghe

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Neuroscience
Belgium
2026

D-Index & Metrics

Neuroscience

D-Index
98
Citations
48256
World Ranking
794
National Ranking
4

Medicine

D-Index
98
Citations
48304
World Ranking
8775
National Ranking
100

Research.com Recognitions

  • 2026 - Research.com Neuroscience in Belgium Leader Award
  • 2025 - Research.com Neuroscience in Belgium Leader Award

Overview

Rik Vandenberghe is affiliated with KU Leuven in Belgium and has contributed extensively to the field of medicine, with a particular focus on physiological and neurological research. Their work spans several subfields including physiology, psychiatry and mental health, neurology, molecular biology, and cognitive neuroscience.

Their research primarily addresses topics such as Alzheimer's disease research and treatments, dementia and cognitive impairment research, amyotrophic lateral sclerosis research, functional brain connectivity studies, Parkinson's disease mechanisms and treatments, prion diseases and protein misfolding, and advanced neuroimaging techniques and applications.

Rik Vandenberghe has published numerous papers, with notable recent works including:

  • Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders (2020, Brain)
  • Pathophysiological subtypes of Alzheimer's disease based on cerebrospinal fluid proteomics (2020, Brain)
  • Pyroptosis in Alzheimer's disease: cell type-specific activation in microglia, astrocytes and neurons (2022, Acta Neuropathologica)
  • Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia (2020, Journal of Neurology Neurosurgery & Psychiatry)
  • Safety and Efficacy of Semorinemab in Individuals With Prodromal to Mild Alzheimer Disease (2022, JAMA Neurology)

Regular co-authors frequently collaborating with Rik Vandenberghe include Markus Otto, Simon Ducharme, Raquel Sánchez-Valle, Caroline Graff, and Barbara Borroni.

Publication venues where Rik Vandenberghe's work appears most often include:

  • Alzheimer s & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Alzheimer s Research & Therapy
  • Brain
  • Neurology

The range and scope of Rik Vandenberghe's research reflect a comprehensive engagement with neurodegenerative diseases and cognitive disorders, integrating clinical and molecular perspectives. Their work contributes to ongoing efforts to understand and develop treatments for complex brain diseases through multidisciplinary approaches.

Best Publications

  • Classification of primary progressive aphasia and its variants

    M L Gorno-Tempini;M L Gorno-Tempini;A E Hillis;S Weintraub;A Kertesz

  • Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

    Unknown

  • New insights into the genetic etiology of Alzheimer’s disease and related dementias

    Unknown

  • Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.

    Willemijn J. Jansen;Rik Ossenkoppele;Dirk L. Knol;Betty M. Tijms

  • Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

    Marc Cruts;Ilse Gijselinck;Julie van der Zee;Sebastiaan Engelborghs

  • Functional anatomy of a common semantic system for words and pictures

    R. Vandenberghe;C. Price;R. Wise;O. Josephs

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification study.

    Ilse Gijselinck;Tim Van Langenhove;Julie van der Zee;Kristel Sleegers

  • 18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment : a phase 2 trial.

    Rik Vandenberghe;Rik Vandenberghe;Koen Van Laere;Adrian Ivanoiu;Eric Salmon

  • Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis.

    Rik Ossenkoppele;Willemijn J Jansen;Gil D Rabinovici;Dirk L Knol

  • Randomized Trial of Verubecestat for Mild-to-Moderate Alzheimer’s Disease

    Michael F. Egan;James Kost;Pierre N. Tariot;Paul S. Aisen

  • The neural systems sustaining face and proper-name processing.

    M L Gorno-Tempini;C J Price;O Josephs;Rik Vandenberghe

  • Consensus classification of posterior cortical atrophy

    Sebastian J. Crutch;Jonathan M. Schott;Gil D. Rabinovici;Melissa Murray

  • The Response of Left Temporal Cortex to Sentences

    R. Vandenberghe;A. C. Nobre;C. J. Price

  • Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology.

    J Chapuis;F Hansmannel;M Gistelinck;A Mounier

  • Amyloid imaging in cognitively normal individuals, at-risk populations and preclinical Alzheimer's disease.

    Gaël Chételat;Renaud La Joie;Nicolas Villain;Audrey Perrotin

  • CSF biomarker variability in the Alzheimer's Association quality control program

    Niklas Mattsson;Niklas Mattsson;Ulf Andreasson;Staffan Persson;Maria C. Carrillo

  • Orienting Attention to Locations in Perceptual Versus Mental Representations

    A. C. Nobre;J. T. Coull;P. Maquet;C. D. Frith

  • Phase 1 Study of the Pittsburgh Compound B Derivative 18F-Flutemetamol in Healthy Volunteers and Patients with Probable Alzheimer Disease

    Natalie Nelissen;Koen Van Laere;Lennart Thurfjell;Rikard Owenius

  • Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum.

    Unknown

  • The importance of appropriate partial volume correction for PET quantification in Alzheimer's disease.

    Benjamin A. Thomas;Kjell Erlandsson;Marc Modat;Lennart Thurfjell

  • A Pan‐European Study of the C9orf72 Repeat Associated with FTLD: Geographic Prevalence, Genomic Instability, and Intermediate Repeats

    Julie van der Zee;Ilse Gijselinck;Lubina Dillen;Tim Van Langenhove

  • Reversible posterior leukoencephalopathy syndrome

    Dimitri Renard;Pierre Labauge;Rik Vandenberghe

Frequent Co-Authors

Sebastiaan Engelborghs
Sebastiaan Engelborghs University of Antwerp
Pieter Jelle Visser
Pieter Jelle Visser Amsterdam University Medical Centers
Peter Paul De Deyn
Peter Paul De Deyn University of Antwerp
Kristel Sleegers
Kristel Sleegers University of Antwerp
Caroline Graff
Caroline Graff Karolinska University Hospital
Giovanni B. Frisoni
Giovanni B. Frisoni University of Geneva
Christine Van Broeckhoven
Christine Van Broeckhoven University of Antwerp

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