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Chemistry

D-Index
42
Citations
7115
World Ranking
17480
National Ranking
1267

Overview

Armin Buschauer was affiliated with the University of Regensburg in Germany. Their research spanned several areas within biochemistry, genetics, molecular biology, and neuroscience, with a significant focus on receptor mechanisms and signaling.

Their main fields of study included:

  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience

Subfields of work included:

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Immunology
  • Bioengineering
  • Oncology

Primary research topics covered:

  • Receptor Mechanisms and Signaling
  • Mast cells and histamine
  • Neuroscience and Neural Engineering
  • Analytical Chemistry and Sensors
  • Drug Transport and Resistance Mechanisms
  • Cancer therapeutics and mechanisms
  • HIV/AIDS drug development and treatment

Buschauer was involved in publications in various scientific journals, frequently contributing to:

  • European Journal of Medicinal Chemistry
  • Journal of Medicinal Chemistry
  • Journal of Visualized Experiments
  • ACS Medicinal Chemistry Letters

Some of their recent published papers include:

  • "Tariquidar-related triazoles as potent, selective and stable inhibitors of ABCG2 (BCRP)" (2020, European Journal of Medicinal Chemistry)
  • "UR-DEBa242: A Py-5-Labeled Fluorescent Multipurpose Probe for Investigations on the Histamine H3 and H4 Receptors" (2020, Journal of Medicinal Chemistry)
  • "Abolishing Dopamine D2long/D3 Receptor Affinity of Subtype-Selective Carbamoylguanidine-Type Histamine H2 Receptor Agonists" (2021, Journal of Medicinal Chemistry)
  • "Pharmacological characterization of a new series of carbamoylguanidines reveals potent agonism at the H2R and D3R" (2021, European Journal of Medicinal Chemistry)
  • "Fluorescent H2 Receptor Squaramide-Type Antagonists: Synthesis, Characterization, and Applications" (2020, ACS Medicinal Chemistry Letters)

Frequently collaborating co-authors included:

  • Günther Bernhardt
  • Katharina Tropmann
  • Peter Gmeiner
  • Timo Littmann
  • Merlin Bresinsky

Best Publications

  • Structural basis of small-molecule inhibition of human multidrug transporter ABCG2.

    Scott M. Jackson;Ioannis Manolaridis;Julia Kowal;Melanie Zechner

  • Reversible and irreversible labeling and autoradiographic localization of the cerebral histamine H2 receptor using [125I]iodinated probes

    M Ruat;E Traiffort;M L Bouthenet;J C Schwartz

  • Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar

    Matthias Kühnle;Michael Egger;Christine Müller;Anne Mahringer

  • Molecular and cellular analysis of human histamine receptor subtypes

    Roland Seifert;Andrea Strasser;Erich H. Schneider;Detlef Neumann

  • Synthesis and in vitro pharmacology of arpromidine and related phenyl(pyridylalkyl)guanidines, a potential new class of positive inotropic drugs.

    Armin Buschauer

  • Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor.

    Zhenlin Yang;Shuo Han;Max Keller;Anette Kaiser

  • L-ascorbic acid-6-hexadecanoate, a potent hyaluronidase inhibitor: X-ray structure and molecular modeling of enzyme-inhibitor complexes

    Alexander Botzki;Daniel J. Rigden;Stephan Braun;Masatoshi Nukui

  • Paradoxical stimulatory effects of the "standard" histamine H4-receptor antagonist JNJ7777120: the H4 receptor joins the club of 7 transmembrane domain receptors exhibiting functional selectivity.

    Roland Seifert;Erich H. Schneider;Stefan Dove;Irena Brunskole

  • Antispasmodic activity of Thymus vulgaris extract on the isolated guinea-pig trachea: discrimination between drug and ethanol effects.

    Adolf Meister;Günther Bernhardt;Volker Christoffel;Armin Buschauer

  • Species-dependent activities of G-protein-coupled receptor ligands: lessons from histamine receptor orthologs

    Andrea Strasser;Hans-Joachim Wittmann;Armin Buschauer;Erich H. Schneider

  • Quantitation of hyaluronidases by the Morgan-Elson reaction: comparison of the enzyme activities in the plasma of tumor patients and healthy volunteers

    Ingo Muckenschnabel;Günther Bernhardt;Thilo Spruss;Barbara Dietl

  • Functional Expression of the Interleukin-11 Receptor α-Chain and Evidence of Antiapoptotic Effects in Human Colonic Epithelial Cells

    Stephan Kiessling;Gerhard Muller-Newen;Sandra N. Leeb;Martin Hausmann

  • Incomplete activation of human eosinophils via the histamine H4-receptor: Evidence for ligand-specific receptor conformations

    Till M. Reher;Detlef Neumann;Armin Buschauer;Roland Seifert

  • Multiple Differences in Agonist and Antagonist Pharmacology between Human and Guinea Pig Histamine H1-Receptor

    Roland Jürgen Seifert;Katharina Wenzel-Seifert;Tilmann Bürckstümmer;Heinz H. Pertz

  • Histamine inhibits activation of human neutrophils and HL-60 leukemic cells via H2-receptors.

    Rahel Burde;Roland Seifert;Armin Buschauer;Günther Schultz

  • Synthesis and Structure−Activity Relationships of Cyanoguanidine-Type and Structurally Related Histamine H4 Receptor Agonists§

    Patrick Igel;Roland Geyer;Andrea Strasser;Stefan Dove

  • Histamine increases cytosolic Ca2+ in HL-60 promyelocytes predominantly via H2 receptors with an unique agonist/antagonist profile and induces functional differentiation.

    Roland Seifert;Ariane Höer;Ingo Schwaner;Armin Buschauer

  • Acylguanidines as bioisosteres of guanidines: NG-acylated imidazolylpropylguanidines, a new class of histamine H2 receptor agonists.

    Prasanta Ghorai;Anja Kraus;Max Keller;Carsten Götte

  • Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells

    Christine Müller;Dietmar Gross;Vasiliki Sarli;Michael Gartner

  • Distinct interaction of human and guinea pig histamine H2-receptor with guanidine-type agonists.

    Melissa T. Kelley;Tilmann Bürckstümmer;Katharina Wenzel-Seifert;Stefan Dove

  • Inhibition of IgE- and non-IgE-mediated histamine release from human basophil leukocytes in vitro by a histamine H1-antagonist, desethoxycarbonyl-loratadine

    Jörg Kleine-Tebbe;Christa Josties;Gabriel Frank;Dirk Stalleicken

  • Reversible and irreversible labeling and autoradiographic localization of the cerebral histamine H_2-receptor

    Martial Ruat;Elisabeth Traiffort;M. L. Bouthenet;Jean-Charles Schwartz

Frequent Co-Authors

Walter Schunack
Walter Schunack Freie Universität Berlin
Roland Seifert
Roland Seifert Hannover Medical School
Burkhard König
Burkhard König University of Regensburg
Oliver Reiser
Oliver Reiser University of Regensburg
Peter Gmeiner
Peter Gmeiner University of Erlangen-Nuremberg
Annette G. Beck-Sickinger
Annette G. Beck-Sickinger Leipzig University
Harald Hübner
Harald Hübner University of Erlangen-Nuremberg
Martial Ruat
Martial Ruat Centre national de la recherche scientifique, CNRS
Elisabeth Traiffort
Elisabeth Traiffort Inserm : Institut national de la santé et de la recherche médicale

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