D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 49 Citations 8,442 116 World Ranking 13677 National Ranking 1093

Overview

What is he best known for?

The fields of study he is best known for:

  • Receptor
  • Biochemistry
  • G protein-coupled receptor

Receptor, Dopamine receptor D2, Adenosine A2A receptor, Biochemistry and Neuroscience are his primary areas of study. In his study, which falls under the umbrella issue of Dopamine receptor D2, Colocalization, Molecular biology, G protein and Cell surface receptor is strongly linked to Dopamine receptor. He interconnects Biophysics and Bimolecular fluorescence complementation in the investigation of issues within Biochemistry.

His Neuroscience study incorporates themes from Metabotropic glutamate receptor 5 and Pharmacology. His work in G protein-coupled receptor tackles topics such as Binding site which are related to areas like Peptide and Chemokine. His study in Cell biology is interdisciplinary in nature, drawing from both Agonist and Metabotropic receptor.

His most cited work include:

  • Presynaptic Control of Striatal Glutamatergic Neurotransmission by Adenosine A1–A2A Receptor Heteromers (465 citations)
  • Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2 receptors (428 citations)
  • Adenosine A2A-Dopamine D2 Receptor-Receptor Heteromerization QUALITATIVE AND QUANTITATIVE ASSESSMENT BY FLUORESCENCE AND BIOLUMINESCENCE ENERGY TRANSFER (377 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Receptor, G protein-coupled receptor, Cell biology, Opioid receptor and Biochemistry. His study on G protein, Dopamine receptor D2 and Ligand is often connected to Adenosine A2A receptor as part of broader study in Receptor. His G protein-coupled receptor research integrates issues from Biophysics, Allosteric regulation, Drug discovery and Förster resonance energy transfer.

His biological study spans a wide range of topics, including Internalization, Endocytosis and Chemokine receptor. The study incorporates disciplines such as Endocrinology, Enteric nervous system, Pharmacology and Enkephalin in addition to Opioid receptor. His Neuroscience research incorporates themes from Metabotropic glutamate receptor 5 and Internal medicine.

He most often published in these fields:

  • Receptor (50.00%)
  • G protein-coupled receptor (40.91%)
  • Cell biology (39.09%)

What were the highlights of his more recent work (between 2018-2021)?

  • Opioid receptor (25.45%)
  • Cell biology (39.09%)
  • Opioid (12.73%)

In recent papers he was focusing on the following fields of study:

His main research concerns Opioid receptor, Cell biology, Opioid, Receptor and Pharmacology. Cell biology connects with themes related to Chemokine receptor in his study. His studies in Opioid integrate themes in fields like Neural function, Addiction and G protein.

His Receptor study frequently links to adjacent areas such as Drug. The Pharmacology study combines topics in areas such as Signal transduction and δ-opioid receptor. As part of one scientific family, Meritxell Canals deals mainly with the area of G protein-coupled receptor, narrowing it down to issues related to the Endocytosis, and often Internalization.

Between 2018 and 2021, his most popular works were:

  • Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists. (67 citations)
  • Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists. (67 citations)
  • Therapeutic targeting of HER2-CB2R heteromers in HER2-positive breast cancer. (20 citations)

In his most recent research, the most cited papers focused on:

  • Receptor
  • Biochemistry
  • Genetics

Meritxell Canals mostly deals with G protein, Opioid, Opioid receptor, Agonist and Receptor. The concepts of his G protein study are interwoven with issues in Intrinsic activity and Functional selectivity. Meritxell Canals has included themes like Drug development and Neuroscience in his Functional selectivity study.

His Opioid receptor study combines topics in areas such as Biophysics, Internalization, Fluorescence recovery after photobleaching and Receptor clustering. His research integrates issues of MAPK/ERK pathway, Opioid peptide, Peptide, Protein kinase C and Endosome in his study of Agonist. His Receptor research is multidisciplinary, incorporating perspectives in Signal transduction, Pharmacology and Tetrapeptide.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Presynaptic Control of Striatal Glutamatergic Neurotransmission by Adenosine A1–A2A Receptor Heteromers

Francisco Ciruela;Vicent Casadó;Ricardo J. Rodrigues;Rafael Luján.
The Journal of Neuroscience (2006)

637 Citations

Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2 receptors

Joëlle A. Hillion;Meritxell Canals;Maria Torvinen;Vicent Casado.
Journal of Biological Chemistry (2002)

605 Citations

Adenosine A2A-Dopamine D2 Receptor-Receptor Heteromerization QUALITATIVE AND QUANTITATIVE ASSESSMENT BY FLUORESCENCE AND BIOLUMINESCENCE ENERGY TRANSFER

Meritxell Canals;Daniel Marcellino;Francesca Fanelli;Francisco Ciruela.
Journal of Biological Chemistry (2003)

529 Citations

Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs

Ron O. Dror;Hillary F. Green;Celine Valant;David W. Borhani.
Nature (2013)

377 Citations

Receptor heteromerization in adenosine A2A receptor signaling Relevance for striatal function and Parkinson’s disease

Kjell Fuxe;L. F. Agnati;K. Jacobsen;J. Hillion.
Neurology (2003)

294 Citations

The role of kinetic context in apparent biased agonism at GPCRs

Carmen Klein Herenbrink;David A. Sykes;Prashant Donthamsetti;Meritxell Canals.
Nature Communications (2016)

271 Citations

Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2A and dopamine D2 receptors.

Francisco Ciruela;Javier Burgueño;Vicent Casadó;Meritxell Canals.
Analytical Chemistry (2004)

267 Citations

Adenosine A2A and dopamine D2 heteromeric receptor complexes and their function

Kjell Fuxe;Sergi Ferré;Meritxell Canals;Maria Torvinen.
Journal of Molecular Neuroscience (2005)

266 Citations

Orexin-1 Receptor-Cannabinoid CB1 Receptor Heterodimerization Results in Both Ligand-dependent and -independent Coordinated Alterations of Receptor Localization and Function

James Ellis;John D. Pediani;Meritxell Canals;Sandra Milasta.
Journal of Biological Chemistry (2006)

259 Citations

Pharmacological modulation of chemokine receptor function

DJ Scholten;M Canals;D Maussang;L Roumen.
British Journal of Pharmacology (2012)

258 Citations

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