What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Cell biology, Heat shock protein, Biochemistry, Kinase and Programmed cell death. His Signal transduction and Chaperone study, which is part of a larger body of work in Cell biology, is frequently linked to Ubiquitins and Peptide binding, bridging the gap between disciplines. His studies in Heat shock protein integrate themes in fields like Apoptosis, Protein folding, c-jun and Proteasome.
His Apoptosis research includes themes of Tumor necrosis factor alpha and Cell. Michael Y. Sherman works mostly in the field of Proteasome, limiting it down to concerns involving Hsp90 and, occasionally, Cancer research. His Biochemistry study incorporates themes from Huntington's disease and Neurodegeneration.
His most cited work include:
- Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases. (900 citations)
- The chaperone function of hsp70 is required for protection against stress-induced apoptosis. (633 citations)
- Hsp70 Prevents Activation of Stress Kinases A NOVEL PATHWAY OF CELLULAR THERMOTOLERANCE (490 citations)
What are the main themes of his work throughout his whole career to date?
Cell biology, Heat shock protein, Biochemistry, Cancer research and Protein aggregation are his primary areas of study. The concepts of his Cell biology study are interwoven with issues in Apoptosis and Aggresome. His work in Heat shock protein tackles topics such as Cancer cell which are related to areas like Hsp90 and Heat shock.
His research on Cancer research also deals with topics like
- Senescence that connect with fields like DNA damage,
- HSF1 which is related to area like Transcription factor. He combines subjects such as Inclusion bodies, Biophysics and Yeast with his study of Protein aggregation. Michael Y. Sherman has included themes like Phosphatase, Dephosphorylation and Programmed cell death in his Kinase study.
He most often published in these fields:
- Cell biology (51.16%)
- Heat shock protein (29.46%)
- Biochemistry (24.81%)
What were the highlights of his more recent work (between 2012-2021)?
- Cell biology (51.16%)
- Chaperone (14.73%)
- Cancer research (16.28%)
In recent papers he was focusing on the following fields of study:
Michael Y. Sherman mostly deals with Cell biology, Chaperone, Cancer research, Cancer cell and Protein aggregation. The various areas that Michael Y. Sherman examines in his Cell biology study include Heat shock protein, Ubiquitin and Transcription factor. His research investigates the connection between Heat shock protein and topics such as Regulation of gene expression that intersect with issues in Cancer.
His studies deal with areas such as HEK 293 cells and Proteotoxicity, Protein folding as well as Chaperone. His biological study spans a wide range of topics, including DNA damage, Genome instability, Mouse mammary tumor virus, Tumor initiation and Cell cycle. His Protein aggregation study combines topics from a wide range of disciplines, such as Biophysics and Aggresome.
Between 2012 and 2021, his most popular works were:
- Hsp70 in cancer: back to the future (123 citations)
- Hsp70-Bag3 interactions regulate cancer-related signaling networks (87 citations)
- Validation of the Hsp70–Bag3 Protein–Protein Interaction as a Potential Therapeutic Target in Cancer (71 citations)
In his most recent research, the most cited papers focused on:
His primary areas of study are Cell biology, Chaperone, Protein aggregation, Cancer research and Aggresome. The Cell biology study combines topics in areas such as Heat shock protein, Cancer and Transcription factor. His research investigates the connection with Heat shock protein and areas like Regulation of gene expression which intersect with concerns in BAG3.
His Chaperone study integrates concerns from other disciplines, such as Biophysics, Ribosome, Proteostasis and Protein biosynthesis. His study in Protein aggregation is interdisciplinary in nature, drawing from both Live cell imaging and Neurodegeneration. Michael Y. Sherman focuses mostly in the field of Cancer research, narrowing it down to matters related to Cell cycle and, in some cases, CD44, Carcinogenesis and Metastasis.
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