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Biology and Biochemistry

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48
Citations
12242
World Ranking
18240
National Ranking
7454

Research.com Recognitions

  • 2015 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Yury O. Chernoff is affiliated with the Georgia Institute of Technology in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions in medicine. The scientist's work covers various subfields, including molecular biology, physiology, cell biology, pulmonary and respiratory medicine, and neurology.

The main topics of Chernoff's research include prion diseases and protein misfolding, Alzheimer's disease research and treatments, endoplasmic reticulum stress and disease, amino acid enzymes and metabolism, ubiquitin and proteasome pathways, fungal and yeast genetics research, and RNA research and splicing.

Frequent publication venues where Chernoff's work appears include:

  • International Journal of Molecular Sciences
  • Life
  • Advances in genetics
  • Cancers
  • Prion

Some recent papers authored or co-authored by Chernoff are:

  • Application of yeast to studying amyloid and prion diseases, 2020, Advances in genetics
  • Functional Mammalian Amyloids and Amyloid-Like Proteins, 2020, Life (authored by Maria S. Rubel, a frequent coauthor)
  • Risk of Alzheimer's Disease in Cancer Patients: Analysis of Mortality Data from the US SEER Population-Based Registries, 2020, Cancers (authored by Roman Mezencev, coauthor)
  • Development of molecular tools for diagnosis of Alzheimer's disease that are based on detection of amyloidogenic proteins, 2021, Prion (authored by Konstantin Yu. Kulichikhin)
  • Regulation of the endocytosis and prion-chaperoning machineries by yeast E3 ubiquitin ligase Rsp5 as revealed by orthogonal ubiquitin transfer, 2021, Cell chemical biology (authored by Yiyang Wang)

Frequent co-authors collaborating with Chernoff include:

  • Aleksandr A. Rubel
  • С. А. Федотов
  • Tatiana A. Chernova
  • Daniel V. Kachkin
  • Maria S. Rubel

Yury O. Chernoff has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) since 2015.

Best Publications

  • Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+].

    Yury O. Chernoff;Susan L. Lindquist;Bun-ichiro Ono;Sergei G. Inge-Vechtomov

  • Gene prediction in novel fungal genomes using an ab initio algorithm with unsupervised training.

    Vardges Ter-Hovhannisyan;Alexandre Lomsadze;Yury O. Chernoff;Mark Borodovsky

  • Gene identification in novel eukaryotic genomes by self-training algorithm

    Alexandre Lomsadze;Vardges Ter-Hovhannisyan;Yury O. Chernoff;Mark Borodovsky

  • Genesis and Variability of [ PSI ] Prion Factors in Saccharomyces cerevisiae

    Irina L. Derkatch;Irina L. Derkatch;Yury O. Chernoff;Yury O. Chernoff;Yury O. Chernoff;Vitaly V. Kushnirov;Sergey G. Inge-Vechtomov

  • Genetic and Environmental Factors Affecting the de novo Appearance of the [PSI + ] Prion in Saccharomyces cerevisiae

    Irina L. Derkatch;Michael E. Bradley;Ping Zhou;Yury O. Chernoff

  • Prions in Yeast

    Susan W. Liebman;Yury O. Chernoff

  • Huntingtin toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1

    Anatoli B. Meriin;Xiaoqian Zhang;Xiangwei He;Gary P. Newnam

  • Deletion analysis of the SUP35 gene of the yeast Saccharomyces cerevisiae reveals two non‐overlapping functional regions in the encoded protein

    Michael D. Ter-Avanesyan;Vitaly V. Kushnirov;Adilya R. Dagkesamanskaya;Svetlana A. Didichenko

  • Multicopy SUP35 gene induces de-novo appearance of psi-like factors in the yeast Saccharomyces cerevisiae.

    Yury O. Chernoff;Irina L. Derkach;Sergey G. Inge-Vechtomov

  • Antagonistic Interactions between Yeast Chaperones Hsp104 and Hsp70 in Prion Curing

    Gary P. Newnam;Renee D. Wegrzyn;Susan L. Lindquist;Yury O. Chernoff

  • Evidence for a Protein Mutator in Yeast: Role of the Hsp70-Related Chaperone Ssb in Formation, Stability, and Toxicity of the [PSI] Prion

    Yury O. Chernoff;Gary P. Newnam;Jaijit Kumar;Kim Allen

  • Mechanism of Prion Loss after Hsp104 Inactivation in Yeast

    Renee D. Wegrzyn;Kavita Bapat;Gary P. Newnam;Amy D. Zink

  • Evolutionary conservation of prion-forming abilities of the yeast Sup35 protein.

    Yury O. Chernoff;Alexey P. Galkin;Eugene Lewitin;Tatiana A. Chernova

  • Hsp70 chaperones as modulators of prion life cycle: novel effects of Ssa and Ssb on the Saccharomyces cerevisiae prion [PSI+].

    Kim D. Allen;Renee D. Wegrzyn;Tatiana A. Chernova;Susanne Müller

  • Abnormal proteins can form aggresome in yeast: aggresome-targeting signals and components of the machinery

    Yan Wang;Anatoli B. Meriin;Nava Zaarur;Nina V. Romanova

  • Genetic study of interactions between the cytoskeletal assembly protein sla1 and prion-forming domain of the release factor Sup35 (eRF3) in Saccharomyces cerevisiae.

    Peggy A. Bailleul;Gary P. Newnam;Judith N. Steenbergen;Yury O. Chernoff

  • Modulation of Prion Formation, Aggregation, and Toxicity by the Actin Cytoskeleton in Yeast

    Elena E. Ganusova;Laura N. Ozolins;Srishti Bhagat;Gary P. Newnam

  • Analysis of prion factors in yeast.

    Yury O Chernoff;Susan M Uptain;Susan L Lindquist

  • Mutations in eukaryotic 18S ribosomal RNA affect translational fidelity and resistance to aminoglycoside antibiotics.

    Y.O. Chernoff;A. Vincent;S.W. Liebman

  • Modulation of Prion-dependent Polyglutamine Aggregation and Toxicity by Chaperone Proteins in the Yeast Model *

    Kavita C. Gokhale;Gary P. Newnam;Michael Y. Sherman;Yury O. Chernoff

Frequent Co-Authors

Keith D. Wilkinson
Keith D. Wilkinson Emory University
Susan W. Liebman
Susan W. Liebman University of Nevada Reno
Michael Y. Sherman
Michael Y. Sherman Ariel University
Andreas S. Bommarius
Andreas S. Bommarius Georgia Institute of Technology
Youri I. Pavlov
Youri I. Pavlov University of Nebraska Medical Center
Tatiana S. Karpova
Tatiana S. Karpova National Institutes of Health
David G. Lynn
David G. Lynn Emory University
Mark Borodovsky
Mark Borodovsky Georgia Institute of Technology
Dmitry A. Gordenin
Dmitry A. Gordenin National Institutes of Health

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