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Immunology

D-Index
46
Citations
11394
World Ranking
4578
National Ranking
2063

Overview

Krisha McKee is affiliated with the National Institute of Allergy and Infectious Diseases in the United States. Their research primarily contributes to the fields of Immunology and Microbiology, Medicine, as well as Biochemistry, Genetics and Molecular Biology. Within these areas, McKee has a notable focus on Virology, Radiology, Nuclear Medicine and Imaging, Molecular Biology, Immunology, and Infectious Diseases.

The scientist's main research topics include HIV Research and Treatment, Monoclonal and Polyclonal Antibodies Research, Glycosylation and Glycoproteins Research, HIV/AIDS drug development and treatment, vaccines and immunoinformatics approaches, Immune Cell Function and Interaction, and T-cell and B-cell Immunology.

McKee has published multiple papers in various academic journals. Some of the recent notable publications include:

  • "Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody," 2020, Proceedings of the National Academy of Sciences
  • "Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition," 2020, Cell Reports
  • "Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen," 2020, Scientific Reports
  • "Potent anti-viral activity of a trispecific HIV neutralizing antibody in SHIV-infected monkeys," 2022, Cell Reports
  • "A matrix of structure-based designs yields improved VRC01-class antibodies for HIV-1 therapy and prevention," 2021, mAbs

Frequent co-authors collaborating with McKee include:

  • Nicole A. Doria-Rose
  • Baoshan Zhang
  • Peter D. Kwong
  • Mark K. Louder
  • John R. Mascola

Common publication venues for McKee's research are:

  • Cell Reports
  • mAbs
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports

Best Publications

  • Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

    Xueling Wu;Zhi Yong Yang;Yuxing Li;Carl Magnus Hogerkorp

  • Focused evolution of hiv-1 neutralizing antibodies revealed by crystal structures and deep sequencing

    John R. Mascola;Gary Nabel;Barton F. Haynes;Xueling Wu

  • Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.

    Nicole A. Doria-Rose;Chaim A. Schramm;Jason Gorman;Penny L. Moore

  • Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.

    Tongqing Zhou;Jiang Zhu;Xueling Wu;Stephanie Moquin

  • Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.

    Jinghe Huang;Byong H. Kang;Elise Ishida;Tongqing Zhou

  • Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

    Rui Kong;Kai Xu;Tongqing Zhou;Priyamvada Acharya

  • Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors

    Tongqing Zhou;Rebecca M. Lynch;Lei Chen;Priyamvada Acharya

  • Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo

    Rebecca S. Rudicell;Young Do Kwon;Sung-Youl Ko;Amarendra Pegu

  • Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques

    Ling Xu;Amarendra Pegu;Ercole Rao;Nicole Doria-Rose

  • Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.

    K. Xu;P. Acharya;R. Kong;C. Cheng

  • Mechanism of Neutralization by the Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01

    Yuxing Li;Sijy O'Dell;Laura M. Walker;Xueling Wu

  • Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.

    Xueling Wu;Xueling Wu;Zhenhai Zhang;Chaim A. Schramm;M. Gordon Joyce

  • New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

    Nicole A. Doria-Rose;Jinal N. Bhiman;Jinal N. Bhiman;Ryan S. Roark;Chaim A. Schramm

  • Staged induction of HIV-1 glycan–dependent broadly neutralizing antibodies

    Mattia Bonsignori;Mattia Bonsignori;Edward F. Kreider;Daniela Fera;R. Ryan Meyerhoff;R. Ryan Meyerhoff

  • Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.

    Ivelin S. Georgiev;Nicole A. Doria-Rose;Tongqing Zhou;Young Do Kwon

  • Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor

    Amarendra Pegu;Zhi Yong Yang;Jeffrey C. Boyington;Lan Wu

  • Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation.

    Tongqing Zhou;Nicole A. Doria-Rose;Cheng Cheng;Guillaume B.E. Stewart-Jones

  • Mining the antibodyome for HIV-1–neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains

    Jiang Zhu;Gilad Ofek;Yongping Yang;Baoshan Zhang

  • Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site

    Ema T. Crooks;Tommy Tong;Bimal Chakrabarti;Kristin Narayan

  • Potent and broad HIV-neutralizing antibodies in memory B cells and plasma.

    La Tonya D. Williams;Gilad Ofek;Sebastian Schätzle;Jonathan R. McDaniel

  • Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

    Kai Xu;Priyamvada Acharya;Rui Kong;Cheng Cheng

Frequent Co-Authors

John R. Mascola
John R. Mascola ModeX Therapeutics
Peter D. Kwong
Peter D. Kwong Columbia University Medical Center
Mark K. Louder
Mark K. Louder National Institute of Allergy and Infectious Diseases
Sijy O'Dell
Sijy O'Dell National Institute of Allergy and Infectious Diseases
Nicole A. Doria-Rose
Nicole A. Doria-Rose National Institute of Allergy and Infectious Diseases
Lawrence Shapiro
Lawrence Shapiro Columbia University
Ivelin S. Georgiev
Ivelin S. Georgiev Vanderbilt University Medical Center
Richard T. Wyatt
Richard T. Wyatt Scripps Research Institute
Robert T. Bailer
Robert T. Bailer National Institute of Allergy and Infectious Diseases
Baoshan Zhang
Baoshan Zhang National Institute of Allergy and Infectious Diseases

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