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Biology and Biochemistry

D-Index
79
Citations
79566
World Ranking
4190
National Ranking
308

Overview

Jürgen Cox is affiliated with the Max Planck Society in Germany and focuses research primarily in biochemistry, genetics, and molecular biology, with additional work in chemistry. Their research spans several subfields including molecular biology, spectroscopy, cell biology, archeology, and ecology.

The primary topics covered in their work include:

  • Advanced Proteomics Techniques and Applications
  • Mass Spectrometry Techniques and Applications
  • Metabolomics and Mass Spectrometry Studies
  • Ubiquitin and proteasome pathways
  • Genomics and Phylogenetic Studies
  • Cellular transport and secretion
  • Molecular Biology Techniques and Applications

Jürgen Cox has contributed to publications in various scientific venues. The most frequent publication sources include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Biotechnology
  • Nature
  • Cancer Cell
  • Journal of Proteome Research

Recent papers authored or coauthored by Cox include:

  • "MaxDIA enables library-based and library-free data-independent acquisition proteomics" (2021, Nature Biotechnology)
  • "MaxQuant Software for Ion Mobility Enhanced Shotgun Proteomics" (2020, Molecular & Cellular Proteomics)
  • "Global detection of human variants and isoforms by deep proteome sequencing" (2023, Nature Biotechnology)
  • "Defining the Adult Neural Stem Cell Niche Proteome Identifies Key Regulators of Adult Neurogenesis" (2020, Cell stem cell)
  • "The dental proteome of Homo antecessor" (2020, Nature)

Jürgen Cox frequently collaborates with several authors including:

  • Frido Welker
  • Sung-Huan Yu
  • Pavel Sinitcyn
  • Christoph Wichmann
  • Şule Yılmaz

The body of work reflects a concentration on proteomics and mass spectrometry developments, encompassing both methodological advances and applications related to cellular processes and molecular profiling in various biological contexts.

Best Publications

  • MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification.

    Jiirgen Cox;Matthias Mann

  • The Perseus computational platform for comprehensive analysis of (prote)omics data.

    Stefka Tyanova;Tikira Temu;Pavel Sinitcyn;Arthur Carlson

  • The PRIDE database and related tools and resources in 2019: improving support for quantification data.

    Yasset Perez-Riverol;Attila Csordas;Jingwen Bai;Manuel Bernal-Llinares

  • Andromeda: a peptide search engine integrated into the MaxQuant environment

    Jürgen Cox;Nadin Neuhauser;Annette Michalski;Richard A. Scheltema

  • Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

    Jürgen Cox;Marco Y. Hein;Christian A. Luber;Igor Paron

  • Quantitative Phosphoproteomics Reveals Widespread Full Phosphorylation Site Occupancy During Mitosis

    Jesper V. Olsen;Michiel Vermeulen;Anna Santamaria;Chanchal Kumar

  • A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances

    Marco Y. Hein;Nina C. Hubner;Ina Poser;Juergen Cox

  • Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast.

    Lyris M. F. de Godoy;Jesper V. Olsen;Jürgen Cox;Michael L. Nielsen

  • A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

    Sebastian A. Wagner;Petra Beli;Brian T. Weinert;Michael L. Nielsen

  • Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling.

    Kirti Sharma;Rochelle C.J. D’Souza;Stefka Tyanova;Christoph Schaab

  • A practical guide to the MaxQuant computational platform for SILAC-based quantitative proteomics

    Jürgen Cox;Ivan Matic;Maximiliane Hilger;Nagarjuna Nagaraj

  • Quantitative, High-Resolution Proteomics for Data-Driven Systems Biology

    Jürgen Cox;Matthias Mann

  • 1D and 2D annotation enrichment: a statistical method integrating quantitative proteomics with complementary high-throughput data.

    Juergen Cox;Matthias Mann

  • Online Parallel Accumulation–Serial Fragmentation (PASEF) with a Novel Trapped Ion Mobility Mass Spectrometer *

    Florian Meier;Andreas David Brunner;Scarlet Koch;Heiner Koch

  • Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry

    Michal Bassani-Sternberg;Eva Bräunlein;Richard Klar;Thomas Engleitner;Thomas Engleitner

  • Quantitative proteomics reveals subset-specific viral recognition in dendritic cells.

    Christian A. Luber;Jürgen Cox;Henning Lauterbach;Ben Fancke

  • A 'proteomic ruler' for protein copy number and concentration estimation without spike-in standards

    Jacek R. Wiśniewski;Marco Y. Hein;Juergen Cox;Matthias Mann

  • Is proteomics the new genomics

    Jürgen Cox;Matthias Mann

  • Securin is required for chromosomal stability in human cells

    Bert Vogelstein;Kenneth W. Kinzler;Prasad Jallepalli;Christoph Lengauer

  • Global, quantitative and dynamic mapping of protein subcellular localization.

    Daniel N. Itzhak;Stefka Tyanova;Jürgen Cox;Georg H. H. Borner

Frequent Co-Authors

Matthias Mann
Matthias Mann Max Planck Institute of Biochemistry
Jesper V. Olsen
Jesper V. Olsen University of Copenhagen
Juri Rappsilber
Juri Rappsilber Technical University of Berlin
Tamar Geiger
Tamar Geiger Tel Aviv University
Frank Sobott
Frank Sobott University of Leeds
Chunaram Choudhary
Chunaram Choudhary University of Copenhagen
Tomas Marques-Bonet
Tomas Marques-Bonet Pompeu Fabra University
Carles Lalueza-Fox
Carles Lalueza-Fox Pompeu Fabra University
María Martinón-Torres
María Martinón-Torres University College London

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