D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 49 Citations 7,741 136 World Ranking 13735 National Ranking 5792

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

Biochemistry, Stratum corneum, Barrier function, Endocrinology and Internal medicine are his primary areas of study. His works in Ceramide and Sphingomyelin are all subjects of inquiry into Biochemistry. He has researched Stratum corneum in several fields, including Biophysics and Epidermis.

His research investigates the link between Barrier function and topics such as Transepidermal water loss that cross with problems in Hairless, Ratón, Immune system, Cyclosporin a and Transplantation. His research in Endocrinology intersects with topics in Inflammation, Immunology, Peroxisome proliferator-activated receptor and Cell biology. His Internal medicine research integrates issues from HaCaT, Downregulation and upregulation and Tunicamycin.

His most cited work include:

  • Sustained Serine Proteases Activity by Prolonged Increase in pH Leads to Degradation of Lipid Processing Enzymes and Profound Alterations of Barrier Function and Stratum Corneum Integrity (239 citations)
  • A Homolog of Drosophila grainy head Is Essential for Epidermal Integrity in Mice (215 citations)
  • Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges. (205 citations)

What are the main themes of his work throughout his whole career to date?

Yoshikazu Uchida mainly investigates Cell biology, Biochemistry, Ceramide, Stratum corneum and Barrier function. His Cell biology research is multidisciplinary, incorporating perspectives in Sphingosine-1-phosphate and Keratinocyte. His Biochemistry study incorporates themes from Epidermis and Epidermis.

His Ceramide research includes elements of Sphingosine, Sphingolipid and Sphingomyelin. His work in Stratum corneum covers topics such as Extracellular which are related to areas like Glucosylceramides. His biological study spans a wide range of topics, including Internal medicine and Endocrinology.

He most often published in these fields:

  • Cell biology (60.87%)
  • Biochemistry (42.86%)
  • Ceramide (36.65%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cell biology (60.87%)
  • Biochemistry (42.86%)
  • Ceramide (36.65%)

In recent papers he was focusing on the following fields of study:

Yoshikazu Uchida mainly investigates Cell biology, Biochemistry, Ceramide, Sphingosine-1-phosphate and Unfolded protein response. Yoshikazu Uchida combines subjects such as Corneocyte, Cornified envelope, Keratinocyte, Cathelicidin and Sphingosine kinase 1 with his study of Cell biology. His study in Keratinocyte is interdisciplinary in nature, drawing from both Lipid signaling, Sphingomyelin, Extracellular, Hyperkeratosis and Epidermis.

His Stratum corneum research extends to Biochemistry, which is thematically connected. His studies in Ceramide integrate themes in fields like Stereochemistry and Pharmacology. His research integrates issues of Cathelicidin antimicrobial peptide and Pathogenesis in his study of Unfolded protein response.

Between 2015 and 2021, his most popular works were:

  • ER stress stimulates production of the key antimicrobial peptide, cathelicidin, by forming a previously unidentified intracellular S1P signaling complex. (33 citations)
  • ER stress stimulates production of the key antimicrobial peptide, cathelicidin, by forming a previously unidentified intracellular S1P signaling complex. (33 citations)
  • Aquatide Activation of SIRT1 Reduces Cellular Senescence through a SIRT1-FOXO1-Autophagy Axis. (23 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Genetics

His scientific interests lie mostly in Cell biology, Endoplasmic reticulum, Unfolded protein response, Ceramide and Cornified envelope. The study incorporates disciplines such as Corneocyte, Sphingosine-1-phosphate, Sphingosine kinase 1, ABCA12 and Keratinocyte in addition to Cell biology. His studies deal with areas such as Matrix metalloproteinase, Cellular differentiation and Keratinocyte migration as well as Sphingosine-1-phosphate.

Endoplasmic reticulum is the subject of his research, which falls under Biochemistry. His research links Mutation with Ceramide. His work deals with themes such as Phenotype, Barrier function, Secretion and Fatty acid, which intersect with Cornified envelope.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Epidermal sphingolipids: Metabolism, function, and roles in skin disorders

Walter M. Holleran;Walter M. Holleran;Yutaka Takagi;Yoshikazu Uchida.
FEBS Letters (2006)

310 Citations

A Homolog of Drosophila grainy head Is Essential for Epidermal Integrity in Mice

Stephen B. Ting;Jacinta Caddy;Nikki Hislop;Tomasz Wilanowski.
Science (2005)

295 Citations

Peroxisome Proliferator-Activated Receptor (PPAR)-β/δ Stimulates Differentiation and Lipid Accumulation in Keratinocytes

Matthias Schmuth;Christopher M. Haqq;William J. Cairns;Julie C. Holder.
Journal of Investigative Dermatology (2004)

285 Citations

Infection and Inflammation Induce LDL Oxidation In Vivo

Riaz A. Memon;Ilona Staprans;Mustafa Noor;Walter M. Holleran.
Arteriosclerosis, Thrombosis, and Vascular Biology (2000)

284 Citations

Epidermal sphingomyelins are precursors for selected stratum corneum ceramides

Yoshikazu Uchida;Mariko Hara;Hiroyuki Nishio;Ellen Sidransky.
Journal of Lipid Research (2000)

272 Citations

Sustained Serine Proteases Activity by Prolonged Increase in pH Leads to Degradation of Lipid Processing Enzymes and Profound Alterations of Barrier Function and Stratum Corneum Integrity

Jean-Pierre Hachem;Jean-Pierre Hachem;Mao-Quiang Man;Debra Crumrine;Yoshikazu Uchida.
Journal of Investigative Dermatology (2005)

263 Citations

Loss of functional ELOVL4 depletes very long-chain fatty acids (≥C28) and the unique ω-O-acylceramides in skin leading to neonatal death

Vidyullatha Vasireddy;Yoshikazu Uchida;Norman Salem;Soo Yeon Kim.
Human Molecular Genetics (2007)

256 Citations

Serine Protease Signaling of Epidermal Permeability Barrier Homeostasis

Jean Pierre Hachem;Jean Pierre Hachem;Evi Houben;Debra Crumrine;Mao Quiang Man.
Journal of Investigative Dermatology (2006)

241 Citations

Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges.

Mao-Qiang Man;Yutaka Hatano;Seung H. Lee;Mona Man.
Journal of Investigative Dermatology (2008)

225 Citations

UVB-Induced Alterations in Permeability Barrier Function: Roles for Epidermal Hyperproliferation and Thymocyte-Mediated Response

Akinori Haratake;Yoshikazu Uchida;Yoshikazu Uchida;Matthias Schmuth;Matthias Schmuth;Osamu Tanno.
Journal of Investigative Dermatology (1997)

210 Citations

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