Barbara E. Brown

Overview

Best Publications

• Human stratum corneum lipids: characterization and regional variations.

  Marilyn A. Lampe;A. L. Burlingame;JoAnne Whitney;Mary L. Williams

  902
  Citations

• THE AGED EPIDERMAL PERMEABILITY BARRIER : STRUCTURAL, FUNCTIONAL, AND LIPID BIOCHEMICAL ABNORMALITIES IN HUMANS AND A SENESCENT MURINE MODEL

  R Ghadially;B E Brown;S M Sequeira-Martin;K R Feingold

  703
  Citations

• Lipopenia and skin barrier abnormalities in DGAT2-deficient mice.

  Scot J. Stone;Heather M. Myers;Steven M. Watkins;Barbara E. Brown

  691
  Citations

• pH directly regulates epidermal permeability barrier homeostasis, and stratum corneum integrity/cohesion.

  Jean-Pierre Hachem;Debra Crumrine;Joachim Fluhr;Joachim Fluhr;Barbara E. Brown

  616
  Citations

• Short-term glucocorticoid treatment compromises both permeability barrier homeostasis and stratum corneum integrity: inhibition of epidermal lipid synthesis accounts for functional abnormalities.

  Jack S. Kao;Joachim W. Fluhr;Joachim W. Fluhr;Mao-Qiang Man;Ashley J. Fowler

  343
  Citations

• The Permeability Barrier in Essential Fatty Acid Deficiency: Evidence for a Direct Role for Linoleic Acid in Barrier Function

  Peter M. Elias;Barbara E. Brown;Vincent A. Ziboh

  320
  Citations

• De novo sterologenesis in the skin. II. Regulation by cutaneous barrier requirements.

  Gopinathan K. Menon;Kenneth R. Feingold;Arthur H. Moser;Barbara E. Brown

  308
  Citations

• Peroxisome Proliferator-Activated Receptor (PPAR)-β/δ Stimulates Differentiation and Lipid Accumulation in Keratinocytes

  Matthias Schmuth;Christopher M. Haqq;William J. Cairns;Julie C. Holder

  298
  Citations

• Co-regulation and interdependence of the mammalian epidermal permeability and antimicrobial barriers.

  Karin M. Aberg;Mao Qiang Man;Richard L. Gallo;Tomas Ganz

  289
  Citations

• Localization and Composition of Lipids in Neonatal Mouse Stratum Granulosum and Stratum Corneum

  Peter M. Elias;Barbara E. Brown;Peter Fritsch;Jon Goerke

  286
  Citations

• Exogenous Nonphysiologic vs Physiologic Lipids: Divergent Mechanisms for Correction of Permeability Barrier Dysfunction

  Man Mao-Qiang;Barbara E. Brown;Suzanna Wu-Pong;Kenneth R. Feingold

  279
  Citations

• Glycerol regulates stratum corneum hydration in sebaceous gland deficient (asebia) mice.

  Joachim W. Fluhr;Joachim W. Fluhr;Man Mao-Qiang;Barbara E. Brown;Philip W. Wertz

  277
  Citations

• Sustained Serine Proteases Activity by Prolonged Increase in pH Leads to Degradation of Lipid Processing Enzymes and Profound Alterations of Barrier Function and Stratum Corneum Integrity

  Jean-Pierre Hachem;Jean-Pierre Hachem;Mao-Quiang Man;Debra Crumrine;Yoshikazu Uchida

  276
  Citations

• Modulations in epidermal calcium regulate the expression of differentiation-specific markers.

  Peter M. Elias;Peter M. Elias;Sung K. Ahn;Sung K. Ahn;Mitsuhiro Denda;Barbara E. Brown

  276
  Citations

• Stratum corneum lipids in disorders of cornification. Steroid sulfatase and cholesterol sulfate in normal desquamation and the pathogenesis of recessive X-linked ichthyosis.

  P M Elias;M L Williams;M E Maloney;J A Bonifas

  255
  Citations

• Cholesterol synthesis is required for cutaneous barrier function in mice

  K R Feingold;M Q Man;G K Menon;S S Cho

  254
  Citations

• Mechanisms by which psychologic stress alters cutaneous permeability barrier homeostasis and stratum corneum integrity

  Eung Ho Choi;Eung Ho Choi;Barbara E. Brown;Barbara E. Brown;Debra Crumrine;Debra Crumrine;Sandra Chang;Sandra Chang

  252
  Citations

• Serine Protease Signaling of Epidermal Permeability Barrier Homeostasis

  Jean Pierre Hachem;Jean Pierre Hachem;Evi Houben;Debra Crumrine;Mao Quiang Man

  252
  Citations

• Peroxisome-Proliferator-Activated Receptor (PPAR)-γ Activation Stimulates Keratinocyte Differentiation

  Man Mao-Qiang;Ashley J. Fowler;Matthias Schmuth;Peggy Lau

  246
  Citations

• Freeze-fracture identification of sterol-digitonin complexes in cell and liposome membranes.

  P M Elias;J Goerke;D S Friend;B E Brown

  220
  Citations