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László G. Kömüves

László G. Kömüves

D-Index & Metrics

Biology and Biochemistry

D-Index
45
Citations
9341
World Ranking
19076
National Ranking
7788

Overview

László G. Kömüves is affiliated with Genentech in the United States and has contributed to research primarily within the fields of Biochemistry, Genetics and Molecular Biology, as well as Immunology and Microbiology. Their work spans topics such as interferon and immune responses, cell death mechanisms and regulation, NF-κB signaling pathways, RNA regulation and disease, cytomegalovirus and herpesvirus research, bacterial identification and susceptibility testing, and antibiotic resistance in bacteria.

Their published papers include:

  • Impaired RIPK1 ubiquitination sensitizes mice to TNF toxicity and inflammatory cell death, 2020, Cell Death and Differentiation
  • ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses, 2021, The Journal of Experimental Medicine
  • Unstable Mechanisms of Resistance to Inhibitors of Escherichia coli Lipoprotein Signal Peptidase, 2020, mBio
  • A solid-phase approach for the synthesis of muramyl dipeptide conjugates for detection of NOD2, 2021, Bioorganic Chemistry
  • Simultaneous substrate and ubiquitin modification recognition by bispecific antibodies enables detection of ubiquitinated RIP1 and RIP2, 2024, Science Signaling

Frequent coauthors collaborating with László G. Kömüves include Tatiana Goncharov, Domagoj Vucic, Matthias Kist, Debra L. Dugger, and Merone Roose-Girma.

Their research contributions have appeared in various publication venues, notably:

  • Cell Death and Differentiation
  • The Journal of Experimental Medicine
  • mBio
  • Bioorganic Chemistry
  • Science Signaling

László G. Kömüves' work covers significant subfields, including Immunology, Molecular Biology, Epidemiology, Cancer Research, and Clinical Biochemistry, supporting a broad investigation into molecular and cellular biological processes related to health and disease.

Best Publications

  • Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis.

    Kim Newton;Debra L. Dugger;Katherine E. Wickliffe;Neeraj Kapoor

  • Ubiquitin Chain Editing Revealed by Polyubiquitin Linkage-Specific Antibodies

    Kim Newton;Marissa L. Matsumoto;Ingrid E. Wertz;Donald S. Kirkpatrick

  • A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain

    Ben Chih;Peter Liu;Yvonne Chinn;Cecile Chalouni

  • Proteins and nucleic acids encoding same

    Carol E. A. Pena;Xiaojia Guo;Richard A. Shimkets;Muralidhara Padigaru

  • Phosphorylation of NLRC4 is critical for inflammasome activation

    Yan Qu;Shahram Misaghi;Anita Izrael-Tomasevic;Kim Newton

  • HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells.

    Wei-Fang Shen;Sophia Rozenfeld;Angela Kwong;Laszlo G. Kömüves

  • Expression and signal transduction of calcium-sensing receptors in cartilage and bone.

    Wenhan Chang;Chialing Tu;Tsui Hua Chen;Laszlo Komuves

  • Modulations in epidermal calcium regulate the expression of differentiation-specific markers.

    Peter M. Elias;Peter M. Elias;Sung K. Ahn;Sung K. Ahn;Mitsuhiro Denda;Barbara E. Brown

  • Frequent co-expression of the HOXA9 and MEIS1 homeobox genes in human myeloid leukemias.

    H. J. Lawrence;S. Rozenfeld;C. Cruz;Karen Matsukuma

  • Differential localization of syntaxin isoforms in polarized Madin-Darby canine kidney cells.

    S H Low;S J Chapin;T Weimbs;L G Kömüves

  • Lack of the vitamin D receptor is associated with reduced epidermal differentiation and hair follicle growth.

    Zhongjion Xie;László Komuves;Qian-Chun Yu;Hashem Elalieh

  • Cellular inhibitors of apoptosis are global regulators of NF-κB and MAPK activation by members of the TNF family of receptors.

    Eugene Varfolomeev;Tatiana Goncharov;Heather Maecker;Kerry Zobel

  • Stimulation of PPARα Promotes Epidermal Keratinocyte Differentiation In Vivo

    László G. Kömüves;Karen Hanley;Anne-Marie Lefebvre;Mao-Qiang Man

  • The SNARE machinery is involved in apical plasma membrane trafficking in MDCK cells.

    Seng Hui Low;Steven J. Chapin;Christian Wimmer;Sidney W. Whiteheart

  • Identification of a novel family of cell-surface proteins expressed in human vascular endothelium.

    Ruey-Bing Yang;Chi Kin Domingos Ng;Scott M. Wasserman;Steven D. Colman

  • Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, participates in platelet contact-induced activation.

    Nisha Nanda;Ming Bao;Hanna Lin;Karl Clauser

  • The Secretory Granular Cell: The Outermost Granular Cell as a Specialized Secretory Cell

    Peter M Elias;Christopher Cullander;Theodora Mauro;Ulrich Rassner

  • The Calcium Sensing Receptor and Its Alternatively Spliced Form in Murine Epidermal Differentiation

    Yuko Oda;Chia-Ling Tu;Wenhan Chang;Debra Crumrine

  • Gene expression profile of human endothelial cells exposed to sustained fluid shear stress.

    Scott M. Wasserman;Fuad Mehraban;Laszlo G. Komuves;Ruey-Bing Yang

  • Hepatitis C Virus Induces Epidermal Growth Factor Receptor Activation via CD81 Binding for Viral Internalization and Entry

    Jingyu Diao;Homer Pantua;Hai Ngu;Laszlo Komuves

Frequent Co-Authors

Peter M. Elias
Peter M. Elias University of California, San Francisco
Kenneth R. Feingold
Kenneth R. Feingold University of California, San Francisco
Corey Largman
Corey Largman University of California, San Francisco
Daniel D. Bikle
Daniel D. Bikle University of California, San Francisco
Zora Modrusan
Zora Modrusan Genentech
Theodora M. Mauro
Theodora M. Mauro University of California, San Francisco
Ruey-Bing Yang
Ruey-Bing Yang Academia Sinica
Domagoj Vucic
Domagoj Vucic Genentech

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