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Molecular Biology

D-Index
68
Citations
18763
World Ranking
1503
National Ranking
107

Overview

Marcus Krüger is affiliated with the University of Cologne in Germany. Their work spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a particular focus on Molecular Biology, Cell Biology, Cardiology and Cardiovascular Medicine, Immunology, and Epidemiology.

The scientist's research topics cover a range of biological and medical subjects including Muscle Physiology and Disorders, Adipose Tissue and Metabolism, Ubiquitin and proteasome pathways, Mitochondrial Function and Pathology, RNA Research and Splicing, Autophagy in Disease and Therapy, and Cardiomyopathy and Myosin Studies.

Marcus Krüger has contributed to multiple papers published in prominent venues. Some of the recent publications include:

  • Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation, 2020, Nature Communications
  • Nicotinamide for the treatment of heart failure with preserved ejection fraction, 2021, Science Translational Medicine
  • Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins, 2021, Nature Communications
  • SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity, 2021, Nature Communications
  • Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1, 2020, Blood

Their work is published frequently in a variety of venues, predominantly including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Blood
  • The EMBO Journal
  • Proceedings of the National Academy of Sciences

Collaboration plays an important role in their research, with recurring co-authors such as Hendrik Nolte, Clara Türk, Sebastian Kallabis, Theresa Bock, and Janica L. Wiederstein.

Best Publications

  • Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy

    Richard S. Finkel;Eugenio Mercuri;Basil T. Darras;Anne M. Connolly

  • Genetic compensation induced by deleterious mutations but not gene knockdowns

    Andrea Rossi;Zacharias Kontarakis;Claudia Gerri;Hendrik Nolte

  • Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction.

    Daniel F Gudbjartsson;Unnur S Bjornsdottir;Unnur S Bjornsdottir;Eva Halapi;Anna Helgadottir

  • SILAC Mouse for Quantitative Proteomics Uncovers Kindlin-3 as an Essential Factor for Red Blood Cell Function

    Marcus Krüger;Markus Moser;Siegfried Ussar;Ingo Thievessen

  • Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster

    Thomas Boettger;Nadine Beetz;Sawa Kostin;Johanna Schneider

  • Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase

    Virginia Guarani;Gianluca Deflorian;Claudio A Franco;Marcus Kruger

  • Use of stable isotope labeling by amino acids in cell culture as a spike-in standard in quantitative proteomics

    Tamar Geiger;Jacek R Wisniewski;Juergen Cox;Sara Zanivan

  • Dissection of the insulin signaling pathway via quantitative phosphoproteomics.

    Marcus Krüger;Irina Kratchmarova;Blagoy Blagoev;Yu-Hua Tseng

  • Systems-wide proteomic analysis in mammalian cells reveals conserved, functional protein turnover.

    Sidney B. Cambridge;Florian Gnad;Chuong Nguyen;Justo Lorenzo Bermejo

  • The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation

    Lourdes Serrano;Paloma Martínez-Redondo;Anna Marazuela-Duque;Berta N. Vazquez

  • Integrin-Linked Kinase Controls Microtubule Dynamics Required for Plasma Membrane Targeting of Caveolae

    Sara A. Wickström;Anika Lange;Michael W. Hess;Julien Polleux

  • Cardiomyocyte-specific IκB kinase (IKK)/NF-κB activation induces reversible inflammatory cardiomyopathy and heart failure

    Harald J. Maier;Tobias G. Schips;Astrid Wietelmann;Marcus Krüger

  • PGM3 mutations cause a congenital disorder of glycosylation with severe immunodeficiency and skeletal dysplasia.

    Asbjørg Stray-Pedersen;Paul H. Backe;Paul H. Backe;Hanne S. Sorte;Lars Mørkrid;Lars Mørkrid

  • A sequence variant on 17q21 is associated with age at onset and severity of asthma

    Eva Halapi;Daniel F Gudbjartsson;Gudrun M Jonsdottir;Unnur S Bjornsdottir;Unnur S Bjornsdottir

  • The lncRNA GATA6-AS epigenetically regulates endothelial gene expression via interaction with LOXL2

    Philipp Neumann;Nicolas Christopher Jaé;Andrea Knau;Simone F. Glaser

  • Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation

    Lucie Laurien;Masahiro Nagata;Hannah Schünke;Tom Delanghe

  • PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis

    Shotaro Saita;Hendrik Nolte;Kai Uwe Fiedler;Hamid Kashkar

  • Prmt5 is a regulator of muscle stem cell expansion in adult mice

    Ting Zhang;Stefan Günther;Mario Looso;Carsten Künne

  • Supervillin couples myosin-dependent contractility to podosomes and enables their turnover

    Ridhirama Bhuwania;Susanne Cornfine;Zhiyou Fang;Marcus Krüger

  • Integrin-linked kinase controls microtubule dynamics required for plasma membrane targeting of caveolae

    S. A. Wickström;A. Lange;M. W. Hess;M. Krüger

Frequent Co-Authors

Thomas Braun
Thomas Braun Max Planck Society
Thomas Langer
Thomas Langer Max Planck Society
Matthias Mann
Matthias Mann Max Planck Institute of Biochemistry
Janine Altmüller
Janine Altmüller University of Cologne
Stefanie Dimmeler
Stefanie Dimmeler Goethe University Frankfurt
Jens C. Brüning
Jens C. Brüning Max Planck Society
Sawa Kostin
Sawa Kostin Max Planck Society
Oliver Kretz
Oliver Kretz Universität Hamburg
Tobias B. Huber
Tobias B. Huber Universität Hamburg
Werner Seeger
Werner Seeger University of Giessen

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