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Biology and Biochemistry

D-Index
68
Citations
12422
World Ranking
7996
National Ranking
3619

Overview

Mats Ljungman is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily spans the domain of biochemistry, genetics, and molecular biology, with a focus on various subfields including molecular biology, cancer research, genetics, epidemiology, and oncology.

The scientist's main research topics encompass RNA modifications and cancer, RNA research and splicing, DNA repair mechanisms, autophagy in disease and therapy, genomics and chromatin dynamics, epigenetics and DNA methylation, and glioma diagnosis and treatment.

Mats Ljungman has contributed to multiple recent research papers that reflect these key areas of study. Some of the notable publications include:

  • Multivalent Proteins Rapidly and Reversibly Phase-Separate upon Osmotic Cell Volume Change, 2020, Molecular Cell
  • The Hydroxyquinoline Analogue YUM70 Inhibits GRP78 to Induce ER Stress-Mediated Apoptosis in Pancreatic Cancer, 2021, Cancer Research
  • ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation, 2021, Nature Cell Biology
  • 3D genome organization contributes to genome instability at fragile sites, 2020, Nature Communications
  • A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair, 2021, Nature Communications

The scientist collaborates frequently with various researchers, including Michelle T. Paulsen, Brian Magnuson, Karan Bedi, Ishwarya Venkata Narayanan, and Nouri Neamati. These collaborations contribute to their diverse research output across multiple scientific domains.

Key publication venues for Mats Ljungman include:

  • ENCODE Datasets
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Nature Communications
  • Journal of Medicinal Chemistry

Best Publications

  • BLOCKAGE OF RNA POLYMERASE AS A POSSIBLE TRIGGER FOR U.V. LIGHT-INDUCED APOPTOSIS

    Mats Ljungman;Fenfen Zhang

  • Inhibition of RNA polymerase II as a trigger for the p53 response

    Mats Ljungman;Fenfen Zhang;Feng Chen;Andrew J Rainbow

  • Dial 9-1-1 for p53: Mechanisms of p53 Activation by Cellular Stress

    Mats Ljungman

  • Transcription - guarding the genome by sensing DNA damage.

    Mats Ljungman;David P. Lane

  • Rate of elongation by RNA polymerase II is associated with specific gene features and epigenetic modifications

    Artur Veloso;Killeen S. Kirkconnell;Brian Magnuson;Benjamin Biewen

  • Oncogenic Function of ATDC in Pancreatic Cancer Through Wnt Pathway Activation and β-catenin Stabilization

    Lidong Wang;David G. Heidt;Cheong J. Lee;Huibin Yang

  • The long non-coding RNA PCAT-1 promotes prostate cancer cell proliferation through cMyc.

    John R. Prensner;Wei Chen;Sumin Han;Matthew K. Iyer

  • H2AX phosphorylation after UV irradiation is triggered by DNA repair intermediates and is mediated by the ATR kinase.

    Sheela Hanasoge;Mats Ljungman

  • Downregulation of EZH2 decreases growth of estrogen receptor-negative invasive breast carcinoma and requires BRCA1.

    M E Gonzalez;X Li;K Toy;M DuPrie

  • Analysis of the androgen receptor–regulated lncRNA landscape identifies a role for ARLNC1 in prostate cancer progression

    Yajia Zhang;Sethuramasundaram Pitchiaya;Marcin Cieślik;Yashar S. Niknafs

  • IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response.

    Felipe J. Núñez;Flor M. Mendez;Padma Kadiyala;Mahmoud S. Alghamri

  • Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus.

    Mario D. Galigniana;Jennifer M. Harrell;Heather M. O'Hagen;Mats Ljungman

  • Use of Bru-Seq and BruChase-Seq for genome-wide assessment of the synthesis and stability of RNA.

    Michelle T. Paulsen;Artur Veloso;Jayendra Prasad;Karan Bedi

  • Large transcription units unify copy number variants and common fragile sites arising under replication stress

    Thomas E. Wilson;Martin F. Arlt;So Hae Park;Sountharia Rajendran

  • Targeting the DNA damage response in cancer.

    Mats Ljungman

  • Efficient protection against oxidative DNA damage in chromatin.

    Mats Ljungman;Philip C. Hanawalt

  • Identifying cis Elements for Spatiotemporal Control of Mammalian DNA Replication

    Jiao Sima;Abhijit Chakraborty;Vishnu Dileep;Marco Michalski

  • Histone Ubiquitination Associates with BRCA1-Dependent DNA Damage Response

    Jiaxue Wu;Michael S.Y. Huen;Lin Yu Lu;Lin Ye

  • The cyclin-dependent kinase inhibitor roscovitine inhibits RNA synthesis and triggers nuclear accumulation of p53 that is unmodified at Ser15 and Lys382.

    Mats Ljungman;Michelle T. Paulsen

  • The Long Non-Coding RNA PCAT-1 Promotes Prostate Cancer Cell

    John R. Prensner;Wei Chen;Sumin Han;Matthew K. Iyer

Frequent Co-Authors

Diane M. Simeone
Diane M. Simeone New York University Langone Medical Center
Theodore S. Lawrence
Theodore S. Lawrence University of Michigan–Ann Arbor
Arul M. Chinnaiyan
Arul M. Chinnaiyan University of Michigan–Ann Arbor
Kenneth P. Nephew
Kenneth P. Nephew Indiana University
Ferhat Ay
Ferhat Ay La Jolla Institute For Allergy & Immunology
Philip C. Hanawalt
Philip C. Hanawalt Stanford University
Costas A. Lyssiotis
Costas A. Lyssiotis University of Michigan–Ann Arbor
Peter Fraser
Peter Fraser Florida State University
Stefan Mundlos
Stefan Mundlos Max Planck Society
Howard C. Crawford
Howard C. Crawford University of Michigan–Ann Arbor

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