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Biology and Biochemistry

D-Index
68
Citations
14118
World Ranking
7917
National Ranking
73

Overview

Jong-Wan Park is affiliated with Seoul National University in South Korea and has contributed extensively to the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their research primarily focuses on Molecular Biology, Cancer Research, Immunology, Surgery, and Otorhinolaryngology.

The scientist has explored a range of topics, notably:

  • Cancer, Hypoxia, and Metabolism
  • Sinusitis and nasal conditions
  • Cancer, Lipids, and Metabolism
  • Immune cells in cancer
  • Diet, Metabolism, and Disease
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Metabolism, Diabetes, and Cancer

Recent publications by Jong-Wan Park include:

  • Fatty-acid-induced FABP5/HIF-1 reprograms lipid metabolism and enhances the proliferation of liver cancer cells, 2020, Communications Biology
  • Ketohexokinase-A acts as a nuclear protein kinase that mediates fructose-induced metastasis in breast cancer, 2020, Nature Communications
  • Tumor regionalization after surgery: Roles of the tumor microenvironment and neutrophil extracellular traps, 2022, Experimental & Molecular Medicine
  • Palmitoylation-driven PHF2 ubiquitination remodels lipid metabolism through the SREBP1c axis in hepatocellular carcinoma, 2023, Nature Communications
  • Neddylation of sterol regulatory element-binding protein 1c is a potential therapeutic target for nonalcoholic fatty liver treatment, 2020, Cell Death and Disease

Jong-Wan Park frequently publishes in several venues, including:

  • Allergy Asthma and Immunology Research
  • Nature Communications
  • Experimental & Molecular Medicine
  • Journal of Allergy and Clinical Immunology
  • Scientific Reports

The scientist has collaborated extensively with several colleagues, with frequent co-authors such as:

  • Hyun-Woo Shin
  • Y KIM
  • Yang-Sook Chun
  • Jiyoung Kim
  • Iljin Kim

Best Publications

  • YC-1: A Potential Anticancer Drug Targeting Hypoxia-Inducible Factor 1

    Eun-Jin Yeo;Yang-Sook Chun;Young-Suk Cho;Jinho Kim

  • STAT3 is a potential modulator of HIF-1-mediated VEGF expression in human renal carcinoma cells

    Joo Eun Jung;Hyun Gyu Lee;Ik Hyun Cho;Doo Hyun Chung

  • Early expression of myocardial HIF-1alpha in response to mechanical stresses: regulation by stretch-activated channels and the phosphatidylinositol 3-kinase signaling pathway.

    Chan-Hyung Kim;Young-Suk Cho;Yang-Sook Chun;Jong-Wan Park

  • Curcumin inhibits hypoxia-inducible factor-1 by degrading aryl hydrocarbon receptor nuclear translocator: a mechanism of tumor growth inhibition.

    Hyunsung Choi;Yang-Sook Chun;Seung-Won Kim;Myung-Suk Kim

  • Nutritional status of gastric cancer patients after total gastrectomy.

    Jae-Moon Bae;Jong-Wan Park;Han-Kwang Yang;Jin-Pok Kim

  • Tumor-associated macrophages enhance tumor hypoxia and aerobic glycolysis

    Hoibin Jeong;Sehui Kim;Beom-Ju Hong;Chan-Ju Lee

  • Jab1 Interacts Directly with HIF-1α and Regulates Its Stability

    Moon Kyoung Bae;Mee Young Ahn;Joo Won Jeong;Myung Ho Bae

  • New anticancer strategies targeting HIF-1.

    Eun-Jin Yeo;Yang-Sook Chun;Jong-Wan Park

  • Inhibitory effect of YC-1 on the hypoxic induction of erythropoietin and vascular endothelial growth factor in Hep3B cells

    Yang Sook Chun;Eun Jin Yeo;Eunjoo Choi;Che Ming Teng

  • Bortezomib inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated repression of hypoxia-inducible factor-1

    Dong Hoon Shin;Yang Sook Chun;Dong Soon Lee;L. Eric Huang

  • Oxygen-dependent and -independent regulation of HIF-1alpha.

    Yang Sook Chun;Myung Suk Kim;Jong Wan Park

  • Human Arrest Defective 1 Acetylates and Activates β-Catenin, Promoting Lung Cancer Cell Proliferation

    Ji Hong Lim;Jong Wan Park;Yang Sook Chun

  • A novel mode of action of YC-1 in HIF inhibition: stimulation of FIH-dependent p300 dissociation from HIF-1{alpha}.

    Shan Hua Li;Dong Hoon Shin;Yang-Sook Chun;Myung Kyu Lee

  • ROS mediate the hypoxic repression of the hepcidin gene by inhibiting C/EBPalpha and STAT-3.

    Si-On Choi;Young-Suk Cho;Hye-Lim Kim;Jong-Wan Park

  • IL-25 as a novel therapeutic target in nasal polyps of patients with chronic rhinosinusitis

    Hyun Woo Shin;Hyun Woo Shin;Dong Kyu Kim;Min Hyun Park;Kyoung Mi Eun

  • Caffeic acid and its synthetic derivative CADPE suppress tumor angiogenesis by blocking STAT3-mediated VEGF expression in human renal carcinoma cells.

    Joo Eun Jung;Hong Sook Kim;Chang Seok Lee;Dae-Hun Park

  • Oxidative Dimerization of PHD2 is Responsible for its Inactivation and Contributes to Metabolic Reprogramming via HIF-1α Activation.

    Gibok Lee;Hyung Sik Won;Yoon Mi Lee;Jae Wan Choi

  • Gastric Epithelial Reactive Oxygen Species Prevent Normoxic Degradation of Hypoxia-inducible Factor-1α in Gastric Cancer Cells

    Jung-Hyun Park;Tae You Kim;Hyun-Soon Jong;Tai Young Kim

  • A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis

    S. Y. Nam;Y. S. Ko;J. Jung;J. Yoon

  • STAT3 inhibits the degradation of HIF-1α by pVHL-mediated ubiquitination

    Joo Eun Jung;Hong Sook Kim;Chang Seok Lee;Yong Jae Shin

Frequent Co-Authors

Woo Ho Kim
Woo Ho Kim Seoul National University
Doo Hyun Chung
Doo Hyun Chung Seoul National University
Yung-Jue Bang
Yung-Jue Bang Seoul National University
Jung Weon Lee
Jung Weon Lee Seoul National University
Seock-Ah Im
Seock-Ah Im Seoul National University Hospital
Jae Bum Kim
Jae Bum Kim Seoul National University
Goo Taeg Oh
Goo Taeg Oh Ewha Womans University
Yoon Kyung Jeon
Yoon Kyung Jeon Seoul National University Hospital
Dong-Kug Choi
Dong-Kug Choi Konkuk University
Minako Nagao
Minako Nagao National Cancer Research Institute, UK

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