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Genetics

D-Index
59
Citations
14288
World Ranking
3229
National Ranking
1402

Overview

Brian D. Gregory is affiliated with the University of Pennsylvania in the United States. Their research primarily focuses on Biochemistry, Genetics, and Molecular Biology, with significant contributions in Molecular Biology, Plant Science, Cancer Research, Electrical and Electronic Engineering, and Public Health, Environmental and Occupational Health.

Their recent publications include studies on RNA modifications and molecular mechanisms in plants and human health. Notable papers include:

  • mRNA adenosine methylase (MTA) deposits m 6 A on pri-miRNAs to modulate miRNA biogenesis in Arabidopsis thaliana, 2020, Proceedings of the National Academy of Sciences
  • Messenger RNA 5' NAD+ Capping Is a Dynamic Regulatory Epitranscriptome Mark That Is Required for Proper Response to Abscisic Acid in Arabidopsis, 2020, Developmental Cell
  • mRNA N6-methyladenosine is critical for cold tolerance in Arabidopsis, 2022, The Plant Journal
  • Electronic cigarette exposure disrupts blood-brain barrier integrity and promotes neuroinflammation, 2020, Brain Behavior and Immunity
  • N6-methyladenosine and RNA secondary structure affect transcript stability and protein abundance during systemic salt stress in Arabidopsis, 2020, Plant Direct

The frequent co-authors they have collaborated with include Xiang Yu, Eric Lyons, Andrew D. L. Nelson, Marianne C. Kramer, and Rong Guo.

Their publications are often found in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Plant Cell
  • Plant Direct
  • Developmental Cell
  • Nature Communications

Their work covers several main topics, including:

  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing
  • Genomics and Phylogenetic Studies
  • Cancer-related molecular mechanisms research
  • HVDC Systems and Fault Protection
  • Plant Disease Resistance and Genetics

Brian D. Gregory's research contributes to understanding RNA-based regulatory mechanisms in both plant and human systems, focusing on modification processes such as methylation and capping, which impact gene expression and stress responses. Their diverse range of study areas also intersects with cancer research and engineering applications, indicating a multidisciplinary approach to molecular biology and related fields.

Best Publications

  • Highly Integrated Single-Base Resolution Maps of the Epigenome in Arabidopsis

    Ryan Lister;Ronan C. O'Malley;Julian Tonti-Filippini;Brian D. Gregory

  • Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape

    Parisha P. Shah;Greg Donahue;Gabriel L. Otte;Brian C. Capell

  • Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development.

    Seth D. Kasowitz;Jun Ma;Stephen J. Anderson;N. Adrian Leu

  • A link between RNA metabolism and silencing affecting Arabidopsis development.

    Brian D. Gregory;Ronan C. O'Malley;Ryan Lister;Mark A. Urich

  • Genome-Wide High-Resolution Mapping of Exosome Substrates Reveals Hidden Features in the Arabidopsis Transcriptome

    Julia A. Chekanova;Julia A. Chekanova;Brian D. Gregory;Sergei V. Reverdatto;Huaming Chen

  • Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease.

    Raffaella Nativio;Greg Donahue;Amit Berson;Yemin Lan

  • Next is now: new technologies for sequencing of genomes, transcriptomes, and beyond.

    Ryan Lister;Brian D Gregory;Joseph R Ecker

  • Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle

    David W. Frederick;Emanuele Loro;Ling Liu;Antonio Davila

  • The Arabidopsis dwarf1 Mutant Is Defective in the Conversion of 24-Methylenecholesterol to Campesterol in Brassinosteroid Biosynthesis

    Sunghwa Choe;Brian P. Dilkes;Brian D. Gregory;Amanda S. Ross

  • The Arabidopsis dwf7/ste1 mutant is defective in the Δ7 sterol C-5 desaturation step leading to brassinosteroid biosynthesis

    Sunghwa Choe;Takahiro Noguchi;Shozo Fujioka;Suguru Takatsuto

  • Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes

    Hernan Lorenzi;Asis Khan;Asis Khan;Michael S Behnke;Michael S Behnke;Sivaranjani Namasivayam

  • Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis

    Anastassios Vourekas;Qi Zheng;Panagiotis Alexiou;Manolis Maragkakis

  • ETHYLENE-INSENSITIVE5 encodes a 5′→3′ exoribonuclease required for regulation of the EIN3-targeting F-box proteins EBF1/2

    Gabriela Olmedo;Hongwei Guo;Brian D. Gregory;Saeid D. Nourizadeh

  • H3K36 methylation promotes longevity by enhancing transcriptional fidelity

    Payel Sen;Weiwei Dang;Greg Donahue;Junbiao Dai

  • N6-Methyladenosine Inhibits Local Ribonucleolytic Cleavage to Stabilize mRNAs in Arabidopsis.

    Stephen J. Anderson;Marianne C. Kramer;Sager J. Gosai;Xiang Yu

  • Spatial and functional relationships among Pol V-associated loci, Pol IV-dependent siRNAs, and cytosine methylation in the Arabidopsis epigenome

    Andrzej T. Wierzbicki;Ross Cocklin;Anoop Mayampurath;Ryan Lister

  • Global analysis of ribosome-associated noncoding RNAs unveils new modes of translational regulation

    Jérémie Bazin;Katja Baerenfaller;Sager J. Gosai;Brian D. Gregory

  • The Functions of RNA-Dependent RNA Polymerases in Arabidopsis

    Matthew R. Willmann;Matthew W. Endres;Rebecca T. Cook;Brian D. Gregory

  • Two Plant Viral Suppressors of Silencing Require the Ethylene-Inducible Host Transcription Factor RAV2 to Block RNA Silencing

    Matthew W. Endres;Brian D. Gregory;Zhihuan Gao;Amy Wahba Foreman

  • Detection of Pol IV/RDR2-dependent transcripts at the genomic scale in Arabidopsis reveals features and regulation of siRNA biogenesis

    Shaofang Li;Lee E. Vandivier;Bin Tu;Lei Gao

Frequent Co-Authors

Li-San Wang
Li-San Wang University of Pennsylvania
Xiang Yu
Xiang Yu Jinan University
Joseph R. Ecker
Joseph R. Ecker Salk Institute for Biological Studies
Muredach P. Reilly
Muredach P. Reilly Columbia University
Eric Lyons
Eric Lyons University of Arizona
Mingyao Li
Mingyao Li University of Pennsylvania
Shelley L. Berger
Shelley L. Berger University of Pennsylvania
Lasse Lindahl
Lasse Lindahl University of Maryland, Baltimore County
F. Brad Johnson
F. Brad Johnson University of Pennsylvania
Blake C. Meyers
Blake C. Meyers University of California, Davis

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