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Genetics

D-Index
69
Citations
38800
World Ranking
2308
National Ranking
1040

Overview

Li-San Wang is affiliated with the University of Pennsylvania in the United States. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with a strong focus on molecular biology and genetics as subfields. Additional areas of study include physiology, neurology, and cancer research.

The main topics covered by Li-San Wang's work include:

  • Genetic Associations and Epidemiology
  • Bioinformatics and Genomic Networks
  • Genomics and Rare Diseases
  • Epigenetics and DNA Methylation
  • Genomics and Phylogenetic Studies
  • Alzheimer's disease research and treatments
  • Gene expression and cancer classification

Li-San Wang has contributed to several publication venues, with frequent appearances in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Alzheimer's & Dementia
  • Journal of Alzheimer's Disease
  • Bioinformatics
  • JAMA Neurology

Frequent coauthors collaborating with Li-San Wang include:

  • Yuk Yee Leung
  • Gerard D. Schellenberg
  • Wan-Ping Lee
  • Lindsay A. Farrer
  • Otto Valladares

Recent papers by Li-San Wang include:

  • Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel, 2020, JAMA Neurology
  • Genetic variants and functional pathways associated with resilience to Alzheimer's disease, 2020, Brain
  • Associations of Sex, Race, and Apolipoprotein E Alleles With Multiple Domains of Cognition Among Older Adults, 2023, JAMA Neurology
  • Polygenic Risk Scores in Alzheimer's Disease Genetics: Methodology, Applications, Inclusion, and Diversity, 2022, Journal of Alzheimer's Disease
  • Reconcile the debate over protective effects of BCG vaccine against COVID-19, 2021, Scientific Reports

Best Publications

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Synaptic, transcriptional and chromatin genes disrupted in autism

    Silvia De Rubeis;Xin-Xin He;Arthur P Goldberg;Christopher S. Poultney

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • Patterns and rates of exonic de novo mutations in autism spectrum disorders

    Benjamin M. Neale;Yan Kou;Li Liu;Avi Ma'Ayan

  • Enhancing CD8 T-cell memory by modulating fatty acid metabolism.

    Erika L. Pearce;Matthew C. Walsh;Pedro J. Cejas;Gretchen M. Harms

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

    Günter U. Höglinger;Nadine M. Melhem;Dennis W. Dickson;Patrick M A Sleiman

  • Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

    Vivianna M. Van Deerlin;Patrick M A Sleiman;Maria Martinez-Lage;Maria Martinez-Lage;Alice Chen-Plotkin

  • Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis

    Scott C. Neu;Judy Pa;Walter Kukull;Duane Beekly

  • Rare structural variants found in attention-deficit hyperactivity disorder are preferentially associated with neurodevelopmental genes

    J. Elia;X. Gai;H. M. Xie;J. C. Perin

  • Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ε4, and the Risk of Late-Onset Alzheimer Disease in African Americans

    Christiane Reitz;Gyungah Jun;Adam Naj;Ruchita Rajbhandary

  • Meta-analysis confirms CR1, CLU, and PICALM as Alzheimer disease risk loci and reveals interactions with APOE genotypes.

    Gyungah Jun;Adam C. Naj;Gary W. Beecham;Li San Wang

  • Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

    Eric M Reiman;Joseph F Arboleda-Velasquez;Yakeel T Quiroz;Matthew J Huentelman

  • PASTA: Ultra-Large Multiple Sequence Alignment for Nucleotide and Amino-Acid Sequences

    Siavash Mirarab;Nam Nguyen;Sheng Guo;Li-San Wang

  • The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila

    Nan Liu;Michael Landreh;Michael Landreh;Kajia Cao;Masashi Abe

  • Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

    David C. Whitcomb;Jessica LaRusch;Alyssa M. Krasinskas;Lambertus Klei

  • Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease.

    Raffaella Nativio;Greg Donahue;Amit Berson;Yemin Lan

  • Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae

    Steve G. Hershman;Qijun Chen;Julia Y. Lee;Marina L. Kozak

  • Rare Complete Knockouts in Humans: Population Distribution and Significant Role in Autism Spectrum Disorders

    Elaine T. Lim;Elaine T. Lim;Soumya Raychaudhuri;Soumya Raychaudhuri;Stephan J. Sanders;Christine Stevens

Frequent Co-Authors

Gerard D. Schellenberg
Gerard D. Schellenberg University of Pennsylvania
Adam C. Naj
Adam C. Naj University of Pennsylvania
Margaret A. Pericak-Vance
Margaret A. Pericak-Vance University of Miami
Richard Mayeux
Richard Mayeux Columbia University
Lindsay A. Farrer
Lindsay A. Farrer Boston University
Jonathan L. Haines
Jonathan L. Haines Case Western Reserve University
Eden R. Martin
Eden R. Martin University of Miami
John Q. Trojanowski
John Q. Trojanowski University of Pennsylvania
Eric Boerwinkle
Eric Boerwinkle The University of Texas Health Science Center at Houston
Badri N. Vardarajan
Badri N. Vardarajan Columbia University

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