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Biology and Biochemistry

D-Index
74
Citations
15740
World Ranking
5738
National Ranking
409

Overview

Joachim Fandrey is affiliated with the University of Duisburg-Essen in Germany and has an extensive publication record focused primarily on biochemistry, genetics, molecular biology, and medicine. Their research contributions cover main fields such as cancer research, immunology, genetics, molecular biology, and physiology.

The scientist's work addresses multiple interconnected topics including:

  • Cancer, Hypoxia, and Metabolism
  • High Altitude and Hypoxia
  • Immune Cells in Cancer
  • Mitochondrial Function and Pathology
  • Hemoglobin Structure and Function
  • Heme Oxygenase-1 and Carbon Monoxide
  • Immune Cell Function and Interaction

Among recent papers authored or co-authored by Joachim Fandrey are the following:

  • Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction, 2022, published in Cell Death and Disease
  • The Importance of Hypoxia-Inducible Factors (HIF-1 and HIF-2) for the Pathophysiology of Inflammatory Bowel Disease, 2020, International Journal of Molecular Sciences
  • NK cells in hypoxic skin mediate a trade-off between wound healing and antibacterial defence, 2021, Nature Communications
  • The transcriptional and regulatory identity of erythropoietin producing cells, 2023, Nature Medicine
  • The transcription factor HIF-1α mediates plasticity of NKp46+ innate lymphoid cells in the gut, 2022, Zurich Open Repository and Archive (University of Zurich)

Frequent co-authors collaborating with Joachim Fandrey include:

  • Sandra Winning
  • Anna Wrobeln
  • Tristan Leu
  • Tina Schönberger
  • Timm Schreiber

The most common venues where Joachim Fandrey has published multiple works are:

  • Pflügers Archiv - European Journal of Physiology
  • Scientific Reports
  • American Journal of Physiology-Cell Physiology
  • The Journal of Immunology
  • Laryngo-Rhino-Otologie

Best Publications

  • Interleukin-1β and Tumor Necrosis Factor- Stimulate DNA Binding of Hypoxia-Inducible Factor-1

    Thomas Hellwig-Bürgel;Karen Rutkowski;Eric Metzen;Joachim Fandrey

  • Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing.

    Eric Metzen;Utta Berchner-Pfannschmidt;Petra Stengel;Jan H. Marxsen

  • Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-κB

    Stilla Frede;Christian Stockmann;Patricia Freitag;Joachim Fandrey

  • Nitric Oxide Impairs Normoxic Degradation of HIF-1α by Inhibition of Prolyl Hydroxylases

    Eric Metzen;Jie Zhou;Wolfgang Jelkmann;Joachim Fandrey

  • Accumulation of HIF-1α under the influence of nitric oxide

    Katrin Britta Sandau;Joachim Fandrey;Bernhard Brüne

  • Oxygen-dependent and tissue-specific regulation of erythropoietin gene expression.

    Joachim Fandrey

  • Role of hydrogen peroxide in hypoxia-induced erythropoietin production.

    J Fandrey;S Frede;W Jelkmann

  • ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia

    J Dürig;H Nückel;M Cremer;A Führer

  • Regulating cellular oxygen sensing by hydroxylation.

    Joachim Fandrey;Thomas A. Gorr;Max Gassmann

  • Monokines inhibiting erythropoietin production in human hepatoma cultures and in isolated perfused rat kidneys.

    W. Jelkmann;H. Pagel;M. Wolff;J. Fandrey

  • In Vivo and In Vitro Regulation of Erythropoietin mRNA: Measurement by Competitive Polymerase Chain Reaction

    J Fandrey;HF Bunn

  • Pericellular PO2 and O2 consumption in monolayer cell cultures

    E. Metzen;M. Wolff;J. Fandrey;W. Jelkmann

  • Erythropoietin mRNA Expression in Human Fetal and Neonatal Tissue

    Christof Dame;Hubert Fahnenstich;Patricia Freitag;Dietmar Hofmann

  • Hypoxia-induced erythropoietin production: a paradigm for oxygen-regulated gene expression.

    Christian Stockmann;Joachim Fandrey

  • Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2.

    Utta Berchner-Pfannschmidt;Hatice Yamac;Buena Trinidad;Joachim Fandrey

  • Oxygen supply and oxygen-dependent gene expression in differentiating embryonic stem cells

    Max Gassmann;Joachim Fandrey;Sandrine Bichet;Maria Wartenberg

  • Regulation of Hypoxia‐Inducible Factors During Inflammation

    Stilla Frede;Utta Berchner-Pfannschmidt;Joachim Fandrey

  • Hypoxia and interleukin-1β stimulate vascular endothelial growth factor production in human proximal tubular cells

    Baha El Awad;Burkhard Kreft;Eva-Maria Wolber;Thomas Hellwig-Bürgel

  • Interleukin 1β and tumour necrosis factor α induce a macrophage‐type of nitric oxide synthase in rat renal mesangial cells

    Josef Pfeilschifter;Peter Rob;Alexander Mülsch;Joachim Fandrey

  • The good, the bad and the ugly in oxygen-sensing: ROS, cytochromes and prolyl-hydroxylases.

    Till Acker;Joachim Fandrey;Helmut Acker

Frequent Co-Authors

Mary S. Wolff
Mary S. Wolff Icahn School of Medicine at Mount Sinai
Max Gassmann
Max Gassmann University of Zurich
Roland H. Wenger
Roland H. Wenger University of Zurich
Thomas Kietzmann
Thomas Kietzmann University of Oulu
Veronika Sexl
Veronika Sexl University of Innsbruck
Michael Hallek
Michael Hallek University of Cologne
Dmitri B. Papkovsky
Dmitri B. Papkovsky University College Cork
Kurt Jungermann
Kurt Jungermann University of Göttingen
Bernhard Brüne
Bernhard Brüne Goethe University Frankfurt
Brian K. Agan
Brian K. Agan Uniformed Services University of the Health Sciences

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