Natalie C. J. Strynadka

What is she best known for?

The fields of study she is best known for:

• Enzyme
• Gene
• Amino acid

Her primary scientific interests are in Biochemistry, Stereochemistry, Enzyme, Hydrolase and Binding site. Her study in Glycosyltransferase, Escherichia coli, Transferase, Oxidoreductase and Mutant is done as part of Biochemistry. Her Stereochemistry study combines topics in areas such as Crystallography, Protein structure, Cofactor and Active site.

Her work in Enzyme addresses issues such as Antibiotic resistance, which are connected to fields such as Penicillin and Lactam. Her Hydrolase research integrates issues from Cleavage, Covalent bond, Beta-lactam, New Delhi metallo-beta-lactamase and Nucleophile. Her studies in Binding site integrate themes in fields like Virulence, Secretion and Effector, Cell biology, Protein folding.

Her most cited work include:

• Crystal structures of the helix-loop-helix calcium-binding proteins. (735 citations)
• Molecular structure of the acyl-enzyme intermediate in β-lactam hydrolysis at 1.7 Å resolution (426 citations)
• Insights into the respiratory electron transfer pathway from the structure of nitrate reductase A (368 citations)

What are the main themes of her work throughout her whole career to date?

Natalie C. J. Strynadka mainly investigates Biochemistry, Stereochemistry, Enzyme, Secretion and Crystal structure. Peptidoglycan, Protein structure, Mutant, Escherichia coli and Sialic acid are the subjects of her Biochemistry studies. Her Stereochemistry research also works with subjects such as

• Active site and related Binding site,
• Transferase and related Glycosyltransferase.

As a member of one scientific family, Natalie C. J. Strynadka mostly works in the field of Enzyme, focusing on Staphylococcus aureus and, on occasion, Antibiotic resistance. Her study in Secretion is interdisciplinary in nature, drawing from both Transport protein, Effector, Cell biology, Virulence and Biophysics. Her work deals with themes such as Type three secretion system and Enteropathogenic Escherichia coli, which intersect with Effector.

She most often published in these fields:

• Biochemistry (40.53%)
• Stereochemistry (32.95%)
• Enzyme (17.80%)

What were the highlights of her more recent work (between 2017-2021)?

• Crystal structure (13.64%)
• Biophysics (9.47%)
• Peptidoglycan (10.61%)

In recent papers she was focusing on the following fields of study:

Natalie C. J. Strynadka focuses on Crystal structure, Biophysics, Peptidoglycan, Bacterial cell structure and Secretion. Her Crystal structure research includes elements of Stereochemistry and Penicillin binding proteins. Her Stereochemistry research includes themes of Heptose, Pyrophosphate and Ceftobiprole.

Cell wall, Enzyme and Biochemistry are inherently bound to her Peptidoglycan studies. The concepts of her Bacterial cell structure study are interwoven with issues in Periplasmic space, Escherichia coli and Bacillus subtilis. Her research in Secretion intersects with topics in Transport protein, Effector, Cell biology, Flagellum and Type three secretion system.

Between 2017 and 2021, her most popular works were:

• Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin. (55 citations)
• Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry. (29 citations)
• T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly. (25 citations)

In her most recent research, the most cited papers focused on:

• Enzyme
• Gene
• Amino acid

Her primary areas of study are Secretion, Bacterial cell structure, Peptidoglycan, Biophysics and Bacterial outer membrane. Her Secretion study combines topics from a wide range of disciplines, such as Transport protein, Cell biology, Host cell membrane and Virulence. Her Bacterial cell structure research integrates issues from Teichoic acid, Cell wall, Bacillus subtilis and Cytoplasm.

Her Teichoic acid research is classified as research in Biochemistry. Natalie C. J. Strynadka has included themes like Type three secretion system, Membrane, Inner membrane, Effector and Heptose in her Bacterial outer membrane study. In her work, Protein structure is strongly intertwined with Stereochemistry, which is a subfield of Hydrolase.