World's Best Scientists 2026 revealed!

Overview

Sonia Bertrand is affiliated with the University of Geneva in Switzerland. Their research spans several fields within the life sciences, with a particular focus on neuroscience, biochemistry, genetics and molecular biology, and medicine. Their work also explores subfields such as neurology and molecular biology.

The scientist has contributed to research on various topics, notably:

  • Vagus Nerve Stimulation Research
  • Nicotinic Acetylcholine Receptors Study
  • Long-Term Effects of COVID-19

Sonia Bertrand's publication record includes work published in the International Journal of Molecular Sciences. One of their recent papers is titled "The SARS-CoV-2 Virus and the Cholinergic System: Spike Protein Interaction with Human Nicotinic Acetylcholine Receptors and the Nicotinic Agonist Varenicline", published in 2023.

Collaborative research is a significant aspect of their work. Frequent coauthors include:

  • Eric C. Carlson
  • Marian S. Macsai
  • Daniel Bertrand
  • Jeffrey Nau

Their investigations focus on the interaction of viral proteins with human molecular systems, specifically analyzing how the SARS-CoV-2 spike protein associates with nicotinic acetylcholine receptors, and exploring therapeutic implications related to nicotinic agonists such as varenicline.

Best Publications

  • A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

    Sabine Couturier;Daniel Bertrand;Jean-Marc Matter;Maria-Clemencia Hernandez

  • Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor.

    F. Revah;D. Bertrand;J.-L Galzi;A. Devillers-Thiéry

  • A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization

    Raymond S. Hurst;Mihaly Hajós;Mario Raggenbass;Theron M. Wall

  • Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic.

    Jean-Luc Galzi;Anne Devillers-Thiery;Nicolas Hussy;Sonia Bertrand

  • Chimaeric nicotinic–serotonergic receptor combines distinct ligand binding and channel specificities

    Jean-Luc Eiselé;Sonia Bertrand;Jean-Luc Galzi;Anne Devillers-Thiéry

  • Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptor.

    D Bertrand;J L Galzi;A Devillers-Thiéry;S Bertrand

  • An Insertion Mutation of the CHRNA4 Gene in a Family With Autosomal Dominant Nocturnal Frontal Lobe Epilepsy

    Ortrud K. Steinlein;Andres Magnusson;Jens Stoodt;Sonia Bertrand

  • Unconventional pharmacology of a neuronal nicotinic receptor mutated in the channel domain

    D Bertrand;A Devillers-Thiéry;F Revah;J L Galzi

  • EVP-6124, a novel and selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors.

    Jos Prickaerts;Nick P. van Goethem;Richard Chesworth;Gideon Shapiro

  • NEURONAL NICOTINIC ALPHA 7 RECEPTOR EXPRESSED IN XENOPUS OOCYTES PRESENTS FIVE PUTATIVE BINDING SITES FOR METHYLLYCACONITINE

    Eleonora Palma;Sonia Bertrand;Tiziano Binzoni;Daniel Bertrand

  • Alpha 5, alpha 3, and non-alpha 3. Three clustered avian genes encoding neuronal nicotinic acetylcholine receptor-related subunits.

    S Couturier;L Erkman;S Valera;D Rungger

  • Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channels.

    A. Devillers-Thiéry;J. L. Galzi;J. L. Eiselé;S. Bertrand

  • A Novel Human Nicotinic Receptor Subunit, α10, That Confers Functionality to the α9-Subunit

    Frédéric Sgard;Eric Charpantier;Sonia Bertrand;Nancy Walker

  • Functional significance of aromatic amino acids from three peptide loops of the α7 neuronal nicotinic receptor site investigated by site‐directed mutagenesis

    Jean-Luc Galzi;Daniel Bertrand;Anne Devillers-Thiéry;Frédéric Revah

  • Mutational Analysis of the Charge Selectivity Filter of the α7 Nicotinic Acetylcholine Receptor

    Pierre-Jean Corringer;Sonia Bertrand;Jean-Luc Galzi;Anne Devillers-Thiéry

  • How mutations in the nAChRs can cause ADNFLE epilepsy.

    D. Bertrand;F. Picard;S. Le Hellard;S. Weiland

  • IDENTIFICATION OF A NEW COMPONENT OF THE AGONIST BINDING SITE OF THE NICOTINIC ALPHA 7 HOMOOLIGOMERIC RECEPTOR

    Pierre-Jean Corringer;Jean-Luc Galzi;Jean-Luc Eiselé;Sonia Bertrand

  • The long internal loop of the alpha 3 subunit targets nAChRs to subdomains within individual synapses on neurons in vivo.

    Brian M. Williams;Murali Krishna Temburni;Marjory Schwartz Levey;Marjory Schwartz Levey;Sonia Bertrand

  • Mutated nicotinic receptors responsible for autosomal dominant nocturnal frontal lobe epilepsy are more sensitive to carbamazepine.

    Fabienne Picard;S Bertrand;O K Steinlein;Daniel Bertrand

  • Properties of neuronal nicotinic acetylcholine receptor mutants from humans suffering from autosomal dominant nocturnal frontal lobe epilepsy

    S Bertrand;S Weiland;S F Berkovic;O K Steinlein

Frequent Co-Authors

Daniel Bertrand
Daniel Bertrand University of Geneva
Jean-Pierre Changeux
Jean-Pierre Changeux Institut Pasteur
Ortrud K. Steinlein
Ortrud K. Steinlein Ludwig-Maximilians-Universität München
Titia K. Sixma
Titia K. Sixma Antoni van Leeuwenhoek Hospital
Anastassis Perrakis
Anastassis Perrakis Antoni van Leeuwenhoek Hospital
August B. Smit
August B. Smit Vrije Universiteit Amsterdam
Samuel F. Berkovic
Samuel F. Berkovic University of Melbourne
Eckart D. Gundelfinger
Eckart D. Gundelfinger Leibniz Institute for Neurobiology
John C. Mulley
John C. Mulley Bangor University
Stylianos E. Antonarakis
Stylianos E. Antonarakis University of Geneva

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