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Steven M. Sine

Steven M. Sine

Mayo Clinic
United States

D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
16782
World Ranking
5708
National Ranking
2704

Steven M. Sine publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Steven M. Sine sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 187 publications — 44th percentile

44% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Steven M. Sine D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Steven M. Sine sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 74 D-Index — 72nd percentile

72% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Steven M. Sine is affiliated with the Mayo Clinic in the United States and specializes in the field of Biochemistry, Genetics and Molecular Biology. Their research outputs primarily focus on Molecular Biology, with additional contributions to Cellular and Molecular Neuroscience, Organic Chemistry, Pharmacology, and Atomic and Molecular Physics, and Optics.

The scientist's main research topics cover:

  • Nicotinic Acetylcholine Receptors Study
  • Ion channel regulation and function
  • Receptor Mechanisms and Signaling
  • Neuropeptides and Animal Physiology
  • Synthesis and Biological Evaluation
  • Cholinesterase and Neurodegenerative Diseases
  • Force Microscopy Techniques and Applications

Steven M. Sine has published extensively in several key scientific journals. Frequent publication venues include:

  • Cell
  • Cellular and Molecular Life Sciences
  • American Journal of Physiology-Lung Cellular and Molecular Physiology
  • British Journal of Pharmacology
  • The Journal of General Physiology

Recent publications by Steven M. Sine include:

  • "Structure and gating mechanism of the α7 nicotinic acetylcholine receptor" (2021, Cell)
  • "Structural mechanisms of α7 nicotinic receptor allosteric modulation and activation" (2024, Cell)
  • "NACHO and 14-3-3 promote expression of distinct subunit stoichiometries of the α4β2 acetylcholine receptor" (2020, Cellular and Molecular Life Sciences)
  • "Mechanism of calcium potentiation of the α7 nicotinic acetylcholine receptor" (2020, The Journal of General Physiology)
  • "Nicotinic receptors in airway disease" (2023, American Journal of Physiology-Lung Cellular and Molecular Physiology)

Frequent co-authors collaborating with Steven M. Sine include:

  • Nuriya Mukhtasimova
  • Simone Mazzaferro
  • Ryan Hibbs
  • Kathiresan Natarajan
  • John R. Strikwerda

Best Publications

  • Data transformations for improved display and fitting of single-channel dwell time histograms

    F.J. Sigworth;S.M. Sine

  • Recent advances in Cys-loop receptor structure and function.

    Steven M. Sine;Andrew G. Engel

  • Congenital myasthenic syndromes: pathogenesis, diagnosis, and treatment.

    Andrew G. Engel;Xin Ming Shen;Duygu Selcen;Steven M. Sine

  • Principal pathway coupling agonist binding to channel gating in nicotinic receptors

    Won Yong Lee;Steven M. Sine

  • Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel

    Cecilia Beatriz Bouzat;Fernanda Andrea Gumilar;Guillermo Federico Spitzmaul;Hai Long Wang

  • Mutation of the acetylcholine receptor α subunit causes a slow-channel myasthenic syndrome by enhancing agonist binding affinity

    Steven M. Sine;Kinji Ohno;Cecilia Bouzat;Anthony Auerbach

  • Congenital myasthenic syndrome caused by prolonged acetylcholine receptor channel openings due to a mutation in the M2 domain of the epsilon subunit.

    Kinji Ohno;David O. Hutchinson;Margherita Milone;Joan M. Brengman

  • Congenital Myasthenic Syndrome Caused by Decreased Agonist Binding Affinity Due to a Mutation in the Acetylcholine Receptor ε Subunit

    Kinji Ohno;Hai Long Wang;Margherita Milone;Nina Bren

  • Functional consequences of agonist-mediated state transitions in the cholinergic receptor. Studies in cultured muscle cells.

    S Sine;P Taylor

  • Activation of Torpedo acetylcholine receptors expressed in mouse fibroblasts. Single channel current kinetics reveal distinct agonist binding affinities.

    Steven M. Sine;Toni Claudio;Fred J. Sigworth

  • Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1.

    Inés Ibañez-Tallon;Julie M. Miwa;Hai Long Wang;Niels C. Adams

  • New Mutations in Acetylcholine Receptor Subunit Genes Reveal Heterogeneity in the Slow-Channel Congenital Myasthenic Syndrome

    Andrew G. Engel;Kinji Ohno;Margherita Milone;Hai Long Wang

  • Molecular dissection of subunit interfaces in the acetylcholine receptor: identification of residues that determine curare selectivity

    Steven M. Sine

  • Detection and trapping of intermediate states priming nicotinic receptor channel opening

    Nuriya Mukhtasimova;Won Yong Lee;Hai Long Wang;Steven M. Sine

  • Sleuthing molecular targets for neurological diseases at the neuromuscular junction

    Andrew G. Engel;Kinji Ohno;Steven M. Sine

  • The nicotinic receptor ligand binding domain

    Steven M. Sine

  • Gamma- and delta-subunits regulate the affinity and the cooperativity of ligand binding to the acetylcholine receptor.

    Steven M. Sine;Toni Claudio

  • Ligand-binding domain of an α7-nicotinic receptor chimera and its complex with agonist.

    Shu Xing Li;Sun Huang;Nina Bren;Kaori Noridomi

  • Current understanding of congenital myasthenic syndromes

    Andrew G Engel;Steven M Sine

  • Acetylcholine receptor M3 domain: stereochemical and volume contributions to channel gating.

    Hai Long Wang;Margherita Milone;Kinji Ohno;Xing Ming Shen

Frequent Co-Authors

Andrew G. Engel
Andrew G. Engel Mayo Clinic
Kinji Ohno
Kinji Ohno Nagoya University
Palmer Taylor
Palmer Taylor University of California, San Diego
J. Andrew McCammon
J. Andrew McCammon University of California, San Diego
Joe Henry Steinbach
Joe Henry Steinbach Washington University in St. Louis
Ivaylo Ivanov
Ivaylo Ivanov Georgia State University
Lin Chen
Lin Chen University of Chicago
Rainer Spanagel
Rainer Spanagel Heidelberg University
Robert C. Griggs
Robert C. Griggs University of Rochester Medical Center
Herbert M. Urbassek
Herbert M. Urbassek Technical University of Kaiserslautern

External Links

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Best Scientists Citing Steven M. Sine

David Beeson

David Beeson

University of Oxford

Publications: 82

Andrew G. Engel

Andrew G. Engel

Mayo Clinic

Publications: 71

Jean-Pierre Changeux

Jean-Pierre Changeux

Institut Pasteur

Publications: 61

Hanns Lochmüller

Hanns Lochmüller

University of Freiburg

Publications: 56

Henry A. Lester

Henry A. Lester

California Institute of Technology

Publications: 54

Jon Lindstrom

Jon Lindstrom

University of Pennsylvania

Publications: 51

Palmer Taylor

Palmer Taylor

University of California, San Diego

Publications: 46

Daniel Bertrand

Daniel Bertrand

University of Geneva

Publications: 43

Kinji Ohno

Kinji Ohno

Nagoya University

Publications: 41

Sarah C. R. Lummis

Sarah C. R. Lummis

University of Cambridge

Publications: 41

Angela Vincent

Angela Vincent

University of Oxford

Publications: 40

Dennis A. Dougherty

Dennis A. Dougherty

California Institute of Technology

Publications: 39

Socrates J. Tzartos

Socrates J. Tzartos

Institut Pasteur

Publications: 36

Joseph W. Lynch

Joseph W. Lynch

University of Queensland

Publications: 36

Roger L. Papke

Roger L. Papke

University of Florida

Publications: 31

Francisco J. Barrantes

Francisco J. Barrantes

National Scientific and Technical Research Council

Publications: 29

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