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Biology and Biochemistry

D-Index
61
Citations
12781
World Ranking
11388
National Ranking
4924

Overview

Joe Henry Steinbach is affiliated with Washington University in St. Louis in the United States. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology, with significant contributions to neuroscience. Steinbach's work encompasses subfields such as molecular biology, cellular and molecular neuroscience, toxicology, cognitive neuroscience, and behavioral neuroscience.

The main topics covered by Steinbach's publications include neuroscience and neuropharmacology research, receptor mechanisms and signaling, nicotinic acetylcholine receptors study, pharmacological receptor mechanisms and effects, bioactive compounds and antitumor agents, neural dynamics and brain function, and stress responses and cortisol.

Steinbach has published extensively in several scientific journals. Frequent publication venues include:

  • Molecular Pharmacology (6 publications)
  • Biophysical Journal (1 publication)
  • Frontiers in Synaptic Neuroscience (1 publication)
  • The Journal of General Physiology (1 publication)
  • ACS Chemical Neuroscience (1 publication)

Recent papers authored by or involving Steinbach are:

  • The Sulfated Steroids Pregnenolone Sulfate and Dehydroepiandrosterone Sulfate Inhibit the α1β3γ2L GABAA Receptor by Stabilizing a Novel Nonconducting State, 2021, Molecular Pharmacology
  • Intrasubunit and Intersubunit Steroid Binding Sites Independently and Additively Mediate α1β2γ2L GABAA Receptor Potentiation by the Endogenous Neurosteroid Allopregnanolone, 2021, Molecular Pharmacology
  • Potentiation of the GABAAR reveals variable energetic contributions by etiocholanolone and propofol, 2023, Biophysical Journal
  • Analysis of Modulation of the ρ1 GABAA Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites, 2020, Molecular Pharmacology
  • Pharmacological and Biophysical Characteristics of Picrotoxin-Resistant, δSubunit-Containing GABAA Receptors, 2021, Frontiers in Synaptic Neuroscience

Steinbach has collaborated frequently with several researchers. Notable frequent coauthors include:

  • Allison L. Germann
  • Gustav Akk
  • Spencer R. Pierce
  • Alex S. Evers
  • Yusuke Sugasawa

Best Publications

  • Local anaesthetics transiently block currents through single acetylcholine-receptor channels.

    E Neher;J H Steinbach

  • Clonal cell lines from the rat central nervous system

    D. Schubert;S. Heinemann;W. Carlisle;H. Tarikas

  • The extracellular patch clamp: a method for resolving currents through individual open channels in biological membranes

    Erwin Neher;Bert Sakmann;Joe Henry Steinbach

  • The distribution of α‐bungarotoxin binding sites on mammalian skeletal muscle developing in vivo

    Stuart Bevan;Joe Henry Steinbach

  • How quickly can GABAA receptors open

    David J. Maconochie;John M. Zempel;Joe Henry Steinbach

  • Bicuculline and Gabazine Are Allosteric Inhibitors of Channel Opening of the GABAA Receptor

    Shinya Ueno;John Bracamontes;Chuck Zorumski;David S. Weiss

  • ACh receptor-rich membrane domains organized in fibroblasts by recombinant 43-kildalton protein.

    William D. Phillips;Carrie Kopta;Paul Blount;Paul D. Gardner

  • Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5

    Jen C. Wang;Carlos Cruchaga;Nancy L. Saccone;Sarah Bertelsen

  • Agonists block currents through acetylcholine receptor channels.

    S.M. Sine;J.H. Steinbach

  • Mechanisms of neurosteroid interactions with GABAA receptors

    Gustav Akk;Douglas F. Covey;Alex S. Evers;Joe Henry Steinbach

  • Pregnenolone sulfate block of GABAA receptors: mechanism and involvement of a residue in the M2 region of the α subunit

    Gustav Akk;John Bracamontes;Joe Henry Steinbach

  • 3beta -hydroxypregnane steroids are pregnenolone sulfate-like GABA(A) receptor antagonists.

    Mingde Wang;Yejun He;Lawrence N. Eisenman;Christopher Fields

  • An analysis of the dose-response relationship at voltage-clamped frog neuromuscular junctions.

    V E Dionne;J H Steinbach;C F Stevens

  • Developmental changes in acetylcholine receptor aggregates at rat skeletal neuromuscular junctions.

    Joe Henry Steinbach

  • Activation of acetylcholine receptors on clonal mammalian BC3H-1 cells by high concentrations of agonist.

    Steven M Sine;J. H. Steinbach

  • Neurosteroid Access to the GABAA Receptor

    Gustav Akk;Hong-Jin Shu;Cunde Wang;Joe Henry Steinbach

  • Appearance of Acetylcholine Receptors During Differentiation of a Myogenic Cell Line

    Jim Patrick;Stephen F. Heinemann;Jon Lindstrom;Dave Schubert

  • The C Terminus of the Human Nicotinic α4β2 Receptor Forms a Binding Site Required for Potentiation by an Estrogenic Steroid

    Ken Paradiso;Jessie Zhang;Joe Henry Steinbach

  • Modulation of GABAA receptor channel gating by pentobarbital

    Joe Henry Steinbach;Gustav Akk

  • The modulation of neurotransmitter synthesis by steroid hormones and insulin.

    D. Schubert;M. LaCorbiere;F.G. Klier;J.H. Steinbach

Frequent Co-Authors

Douglas F. Covey
Douglas F. Covey Washington University in St. Louis
Charles F. Zorumski
Charles F. Zorumski Washington University in St. Louis
Steven Mennerick
Steven Mennerick Washington University in St. Louis
David Schubert
David Schubert Salk Institute for Biological Studies
Steven M. Sine
Steven M. Sine Mayo Clinic
Alison Goate
Alison Goate Icahn School of Medicine at Mount Sinai
Stephen F. Heinemann
Stephen F. Heinemann Salk Institute for Biological Studies
Laura J. Bierut
Laura J. Bierut Washington University in St. Louis
Joshua R. Sanes
Joshua R. Sanes Harvard University
Charles F. Stevens
Charles F. Stevens Salk Institute for Biological Studies

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