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Medicine

D-Index
91
Citations
27455
World Ranking
11843
National Ranking
6073

Research.com Recognitions

  • 2012 - Member of the National Academy of Medicine (NAM)

Overview

Charles F. Zorumski is affiliated with Washington University in St. Louis in the United States. Their research spans multiple interconnected areas within neuroscience and medicine, with a focus on understanding brain function and disorders.

Zorumski's main fields of study include:

  • Neuroscience
  • Medicine

In terms of subfields, their work primarily covers:

  • Cellular and Molecular Neuroscience
  • Molecular Biology
  • Cognitive Neuroscience
  • Pharmacology
  • Neurology

The primary topics explored in their research are:

  • Neuroscience and Neuropharmacology Research
  • Treatment of Major Depression
  • Tryptophan and brain disorders
  • Pharmacological Receptor Mechanisms and Effects
  • Receptor Mechanisms and Signaling
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Cholesterol and Lipid Metabolism

Zorumski's publication record includes contributions to several frequently appearing venues, most notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • JAMA Psychiatry
  • Biological Psychiatry
  • Scientific Reports
  • Neuroscience & Biobehavioral Reviews

Among recent papers are:

  • "Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19" (2020, JAMA)
  • "A phase 2 trial of inhaled nitrous oxide for treatment-resistant major depression" (2021, Science Translational Medicine)
  • ""What Were You Before the War?" Repurposing Psychiatry During the COVID-19 Pandemic" (2020, The Journal of Clinical Psychiatry)
  • "Ketamine and nitrous oxide: The evolution of NMDA receptor antagonists as antidepressant agents" (2020, Journal of the Neurological Sciences)
  • "Electroconvulsive therapy in treatment resistant depression" (2021, Journal of the Neurological Sciences)

Zorumski has worked frequently with a core group of collaborators, including:

  • Steven Mennerick
  • Yukitoshi Izumi
  • Eric J. Lenze
  • Angela M. Reiersen
  • Peter Lambert

Recognition includes membership in the National Academy of Medicine (NAM), awarded in 2012.

Best Publications

  • Early Exposure to Common Anesthetic Agents Causes Widespread Neurodegeneration in the Developing Rat Brain and Persistent Learning Deficits

    Vesna Jevtovic-Todorovic;Richard E. Hartman;Yukitoshi Izumi;Nicholas D. Benshoff

  • Nitrous oxide (laughing gas) is an NMDA antagonist, neuroprotectant and neurotoxin

    V Jevtović-Todorović;S M Todorović;S Mennerick;S Powell

  • Functional network dysfunction in anxiety and anxiety disorders

    Chad Sylvester;Maurizio Corbetta;Marcus Raichle;T. L. Rodebaugh

  • Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19: A Randomized Clinical Trial.

    Eric J. Lenze;Caline Mattar;Charles F. Zorumski;Angela Stevens

  • The functional anatomy and pathology of lithium-pilocarpine and high-dose pilocarpine seizures.

    D.B. Clifford;J.W. Olney;A. Maniotis;R.C. Collins

  • Glial contributions to excitatory neurotransmission in cultured hippocampal cells

    Steven Mennerick;Charles F. Zorumski

  • L-cysteine, a bicarbonate-sensitive endogenous excitotoxin

    John W. Olney;Charles Zorumski;Madelon T. Price;Joann Labruyere

  • Noradrenergic Regulation of Synaptic Plasticity in the Hippocampal CA1 Region

    Hiroshi Katsuki;Yukitoshi Izumi;Charles F. Zorumski

  • Inhibition of long-term potentiation by NMDA-mediated nitric oxide release.

    Yukitoshi Izumi;David B. Clifford;Charles F. Zorumski

  • Ketamine, Phencyclidine, and MK‐801 Protect Against Kainic Acid‐Induced Seizure‐Related Brain Damage

    David B. Clifford;John W. Olney;Ann M. Benz;Terry A. Fuller

  • Platelet-activating factor as a potential retrograde messenger in CA1 hippocampal long-term potentiation

    Kunio Kato;Gary D. Clark;Nicolas G. Bazan;Charles F. Zorumski

  • Redox modulation of T-type calcium channels in rat peripheral nociceptors.

    Slobodan M. Todorovic;Vesna Jevtovic-Todorovic;Adam Meyenburg;Steven Mennerick

  • Dimethyl Sulfoxide (DMSO) Produces Widespread Apoptosis in the Developing Central Nervous System

    Jennifer L. Hanslick;Karen Lau;Kevin K. Noguchi;John W. Olney

  • Enhancement of hippocampal excitatory synaptic transmission by platelet-activating factor

    Gary D. Clark;Leo T. Happel;Charles F. Zorumski;Nicolas G. Bazan

  • The Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is a Potent Allosteric Modulator of N-Methyl-d-Aspartate Receptors

    Steven M. Paul;James J. Doherty;Albert J. Robichaud;Gabriel M. Belfort

  • A benzodiazepine recognition site associated with the non-NMDA glutamate receptor

    Charles F. Zorumski;Kelvin A. Yamada;Madelon T. Price;John W. Olney

  • Ketamine: NMDA receptors and beyond

    Charles F. Zorumski;Yukitoshi Izumi;Steven Mennerick

  • Rapid desensitization of glutamate receptors in vertebrate central neurons.

    Laurence O. Trussell;Liu Lin Thio;Charles F. Zorumski;Gerald D. Fischbach

  • Effect of Nitrous Oxide on Excitatory and Inhibitory Synaptic Transmission in Hippocampal Cultures

    Steven Mennerick;Vesna Jevtovic-Todorovic;Slobodan M. Todorovic;Weixing Shen

  • Nitric oxide inhibitors attenuate excitotoxicity in rat hippocampal slices

    Yukitoshi Izumi;Ann M. Benz;David B. Clifford;Charles F. Zorumski

Frequent Co-Authors

Steven Mennerick
Steven Mennerick Washington University in St. Louis
Yukitoshi Izumi
Yukitoshi Izumi Washington University in St. Louis
Douglas F. Covey
Douglas F. Covey Washington University in St. Louis
David B. Clifford
David B. Clifford Washington University in St. Louis
John W. Olney
John W. Olney Washington University in St. Louis
Joe Henry Steinbach
Joe Henry Steinbach Washington University in St. Louis
Slobodan M. Todorovic
Slobodan M. Todorovic University of Colorado Anschutz Medical Campus
Steven M. Paul
Steven M. Paul Washington University in St. Louis
Steven M. Paul
Steven M. Paul University of California, San Francisco
Nicolas G. Bazan
Nicolas G. Bazan Louisiana State University

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