Graziano Pinna

Best Publications

• Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis.

  Roberto C. Agís-Balboa;Graziano Pinna;Adrian Zhubi;Ekrem Maloku

  428
  Citations

• Decreased cerebrospinal fluid allopregnanolone levels in women with posttraumatic stress disorder.

  Ann M. Rasmusson;Ann M. Rasmusson;Graziano Pinna;Prashni Paliwal;David Weisman

  322
  Citations

• Fluoxetine and norfluoxetine stereospecifically and selectively increase brain neurosteroid content at doses that are inactive on 5-HT reuptake

  Graziano Pinna;Erminio Costa;Alessandro Guidotti

  285
  Citations

• Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice.

  Lucio Tremolizzo;Mohemed Salim Doueiri;Erbo Dong;Dennis R. Grayson

  282
  Citations

• Decreased corticolimbic allopregnanolone expression during social isolation enhances contextual fear: A model relevant for posttraumatic stress disorder

  Fabio Pibiri;Marianela Nelson;Alessandro Guidotti;Erminio Costa

  268
  Citations

• In socially isolated mice, the reversal of brain allopregnanolone down-regulation mediates the anti-aggressive action of fluoxetine

  Graziano Pinna;Erbo Dong;Kinzo Matsumoto;Erminio Costa

  248
  Citations

• Epigenetic GABAergic Targets in Schizophrenia and Bipolar Disorder

  Alessandro Guidotti;James Auta;Y. Chen;John M. Davis

  232
  Citations

• The socially-isolated mouse: a model to study the putative role of allopregnanolone and 5α-dihydroprogesterone in psychiatric disorders

  A Guidotti;E Dong;K Matsumoto;G Pinna

  199
  Citations

• Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice.

  Roberto C. Agís-Balboa;Graziano Pinna;Fabio Pibiri;Bashkim Kadriu

  187
  Citations

• Social isolation stress-induced aggression in mice: a model to study the pharmacology of neurosteroidogenesis.

  Kinzo Matsumoto;Graziano Pinna;Giuli Puia;Alessandro Guidotti

  184
  Citations

• SSRIs act as selective brain steroidogenic stimulants (SBSSs) at low doses that are inactive on 5-HT reuptake

  Graziano Pinna;Erminio Costa;Alessandro Guidotti

  169
  Citations

• GABAA receptor neurotransmission dysfunction in a mouse model of social isolation-induced stress: Possible insights into a non-serotonergic mechanism of action of SSRIs in mood and anxiety disorders

  Kinzo Matsumoto;Giulia Puia;Erbo Dong;Graziano Pinna

  166
  Citations

• Brain allopregnanolone regulates the potency of the GABAA receptor agonist muscimol

  G Pinna;V Uzunova;K Matsumoto;G Puia

  159
  Citations

• Neurosteroid biosynthesis down-regulation and changes in GABAA receptor subunit composition: a biomarker axis in stress-induced cognitive and emotional impairment.

  Andrea Locci;Graziano Pinna

  153
  Citations

• Permissive role of brain allopregnanolone content in the regulation of pentobarbital-induced righting reflex loss

  Kinzo Matsumoto;Veska Uzunova;Graziano Pinna;Graziano Pinna;Kazuhiro Taki

  143
  Citations

• Chronic intermittent ethanol (CIE) administration in rats decreases levels of neurosteroids in hippocampus, accompanied by altered behavioral responses to neurosteroids and memory function.

  Elisabetta Cagetti;Graziano Pinna;Alessandro Guidotti;Kate Baicy

  142
  Citations

• Neurosteroid Biosynthesis Regulates Sexually Dimorphic Fear and Aggressive Behavior in Mice

  Graziano Pinna;Roberto Carlos Agis-Balboa;Fabio Pibiri;Marianela Nelson

  135
  Citations

• Phenolic and tyrosyl ring iodothyronine deiodination and thyroid hormone concentrations in the human central nervous system

  Angel Campos-barros;Thomas Hoell;Alberto Musa;Simone Sampaolo

  134
  Citations

• S-adenosyl methionine and DNA methyltransferase-1 mRNA overexpression in psychosis.

  Alessandro Guidotti;William Ruzicka;Dennis R. Grayson;Marin Veldic

  125
  Citations

• Changes in brain testosterone and allopregnanolone biosynthesis elicit aggressive behavior

  Graziano Pinna;Erminio Costa;Alessandro Guidotti

  120
  Citations