Reelin, DAB1, Molecular biology, Neuroscience and DNA methylation are his primary areas of study. His Reelin study combines topics from a wide range of disciplines, such as Endocrinology, Chromatin remodeling, GABAergic and Clozapine. His work deals with themes such as Regulation of gene expression, Regulatory sequence, Enhancer, Nuclear protein and Binding site, which intersect with Molecular biology.
His studies examine the connections between Neuroscience and genetics, as well as such issues in Cell biology, with regards to Tropomyosin receptor kinase B, Forebrain, Tropomyosin receptor kinase A and Neurotrophic factors. His DNA methylation research is multidisciplinary, incorporating perspectives in Chromatin, Methylation and Epigenetics. His Methylation study combines topics in areas such as Promoter and DNA demethylation.
His primary areas of study are Molecular biology, Epigenetics, Reelin, DNA methylation and Neuroscience. His Molecular biology research integrates issues from Enhancer, Gene expression, Gene, GABAA receptor and Binding site. His work carried out in the field of Epigenetics brings together such families of science as Endocrinology, Schizophrenia, Psychosis, Internal medicine and Regulation of gene expression.
His research investigates the connection between Endocrinology and topics such as Protein subunit that intersect with issues in Cerebellum. His specific area of interest is Reelin, where he studies DAB1. Dennis R. Grayson has included themes like Methylation and Chromatin remodeling in his DNA methylation study.
His scientific interests lie mostly in Epigenetics, DNA methylation, Genetics, Endocrinology and Internal medicine. His Epigenetics research incorporates elements of Schizophrenia, Psychiatry, Bioinformatics, Regulation of gene expression and Neuroscience. The study incorporates disciplines such as Chromatin and Phenotype in addition to Neuroscience.
Dennis R. Grayson has researched DNA methylation in several fields, including Molecular biology, Reelin and Methylation. His studies deal with areas such as Cancer research, Clozapine, Promoter, Chromatin remodeling and Antipsychotic as well as Reelin. His Endocrinology study incorporates themes from Offspring, Neurotrophic factors, Allopregnanolone and GABAA receptor.
Dennis R. Grayson mostly deals with DNA methylation, Reelin, Epigenetics, Endocrinology and Internal medicine. His studies in DNA methylation integrate themes in fields like Molecular biology, Methylation, Chromatin remodeling and GAD1. His Molecular biology research incorporates themes from Dentate gyrus, Regulation of gene expression, Striatum and Piriform cortex.
His biological study spans a wide range of topics, including Promoter and DNA demethylation. His Endocrinology research includes themes of Offspring and Neuroscience. His study in GABAergic is interdisciplinary in nature, drawing from both Synaptic plasticity, Schizophrenia, Postsynaptic potential, DAB1 and Dendritic spine.
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Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: A postmortem brain study
Alessandro Guidotti;James Auta;John M. Davis;Valeria DiGiorgi Gerevini.
Archives of General Psychiatry (2000)
Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genes.
R. H. Costa;Dennis R. Grayson;J. E. Darnell.
Molecular and Cellular Biology (1989)
Reelin promoter hypermethylation in schizophrenia.
Dennis R. Grayson;Xiaomei Jia;Ying Chen;Rajiv P. Sharma.
Proceedings of the National Academy of Sciences of the United States of America (2005)
Altering the course of schizophrenia: progress and perspectives
Mark J. Millan;Annie Andrieux;George Bartzokis;Kristin Cadenhead.
Nature Reviews Drug Discovery (2016)
An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability
L. Tremolizzo;G. Carboni;W. B. Ruzicka;C. P. Mitchell.
Proceedings of the National Academy of Sciences of the United States of America (2002)
Developmental and mature expression of full-length and truncated TrkB receptors in the rat forebrain.
Robert H. Fryer;David R. Kaplan;Stuart C. Feinstein;Monte J. Radeke.
The Journal of Comparative Neurology (1996)
DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains.
M. Veldic;H. J. Caruncho;W. S. Liu;J. Davis.
Proceedings of the National Academy of Sciences of the United States of America (2004)
GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon
Alessandro Guidotti;James Auta;John M. Davis;Erbo Dong.
On the epigenetic regulation of the human reelin promoter
Ying Chen;Rajiv P. Sharma;Robert H. Costa;Erminio Costa.
Nucleic Acids Research (2002)
Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation
E. Dong;M. Nelson;D. R. Grayson;E. Costa.
Proceedings of the National Academy of Sciences of the United States of America (2008)
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